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Biomedical subjects

P Foucaud

Publications and source records attributed to P Foucaud.

At least 55 records · Page 3Linked to original sources

[The association of megaesophagus, Binder's syndrome and dysautonomia: a new neurocristopathy].

A case of esophageal achalasia is reported in a 12 year-old child. Nasal hypoplasia (Binder syndrome) and dysautonomia were associated. This may be explained by the common embryologic origin (neural crests) of nasal bud, autonomic nervous system and digestive intramural neurons. Such a neurocristopathy suggests exploration of the autonomic nervous system in cases of esophageal achalasia.

Autonomic Nervous System Diseases↗

[Primary intestinal lymphangiectasis with antenatal manifestation].

Antenatal ascites diagnosed by ultrasound examination was punctured and shunted in utero. Radiologic, endoscopic and histologic data led to diagnosis of primitive intestinal lymphangiectasia during the second year of life. Antenatal revelation of Waldmann's disease is extremely rare in pediatric literature.

Ascites↗

[Percutaneous extraction of pigment lithiasis of the choledochus in an infant].

The authors present the first report of a pigment gallstone of the common bile duct in a 2 month-old infant treated in a non-surgical manner. The gallstone extraction was percutaneous, by a small catheter introduced in the biliary tract under ultrasound control. The clinical and ultrasonographic follow-up (19 months) confirmed complete recovery. This new therapeutic modality might avoid surgery for primary common bile duct cholelithiasis.

Biliary Tract↗

[Intestinal pseudo-obstruction and cytomegalovirus infection of myenteric plexuses].

The authors report an intestinal pseudo-obstruction syndrome occurring in a 2 month-old boy, with acquired major and persistent abdominal distension, leading to total parenteral nutrition. Rectal biopsy revealed hypoganglionosis with thickening of nerve processes and intranuclear inclusions in some neurons. Suspected cytomegalovirus infection was confirmed by viruria and specific IgM and IgG antibodies.

Autonomic Nervous System Diseases↗

[Cardiac failure complicating laryngomalacia in a newborn infant].

A case of cardiac failure with pulmonary hypertension in a neonate with laryngomalacia is described. The interest of clinical and echocardiographical follow up and transcutaneous blood gas measurements to monitor the course of any upper airway obstruction is emphasized.

Airway Obstruction↗

[Value of digestive manometry in scleroderma of childhood].

The authors report a case of systemic scleroderma in a 7 year-old boy, with digestive, cardiac and cutaneous involvement. They stress for the first time the pediatric significance of esophageal and recto-anal manometry from an etiologic topographic point of view.

Child↗

[Recurrent multifocal periostosis in childhood. 2 case reports (author's transl)].

Two children (4 2/12 and 7 years old, respectively) presented with features of recurrent multifocal periostosis. Radiologic findings consist of periosteal appositions, preferentially located on the long bones and are associated with general and local inflammatory signs. No causal agent can be identified. Complete clinical recovery occurs spontaneously sometimes after several relapses. The relationship between these patients' history and Caffey's syndrome is discussed.

Bone Diseases↗

Gastric pepsin and acid secretion during total parenteral nutrition and constant-rate enteral nutrition in infancy.

Total Parenteral Nutrition (TPN) and constant rate enteral nutrition (CREN) are widely used: their effects on gastric function, especially pepsin secretion, are unknown. Basal and pentagastrin-stimulated pepsin (BPO, MPO) and acid (BAO, MAO) secretions were measured in three groups of infants: controls (14 infants fed normally), TPN groups (seven infants on TPN), CREN groups (14 infants on CREN). The MAO and MPO of the TPN group were significantly lower than controls (p less than 0.02), and the ratio of pentagastrin-stimulated PO/AO did not change, suggesting a large decrease of acid gastric function in the TPN group. BPO was not different from controls and BAO was significantly higher because of amino acids perfusion. The data for CREN group were not different from those of the control group, despite the fact that 11 infants were on TPN before CREN. These results demonstrate that TPN causes decreases in both acid and pepsin secretions in human infants. When TPN children are placed on CREN, these secretions return to normal.

Enteral Nutrition↗

[Pediatric imported malaria. Experience of the hospital center of Versailles (1997-2001)].

UNLABELLED: Few data are available about pediatric imported malaria, whereas the number of cases seems in constant increase. PATIENTS AND METHODS: all pediatric malaria cases diagnosed by a positive thin or thick blood film at the Versailles Hospital, from January 1997 to December 2001, were studied retrospectively. RESULTS: sixty cases of pediatric imported malaria were studied. They were 58 cases of uncomplicated malaria and 2 cases of severe malaria; 85% of the children had travelled to sub-Saharan Africa and 15% to Oceania; 90% of the children were of African origin. Plasmodium falciparum was found alone in 84% of the cases. The anti-malarial chemoprophylaxis was inappropriate in 92% of the cases. No child had profited from preventive measures against mosquitos. Fever > 37,5 degrees C was observed in 100% of the cases. The other clinical signs were present in less than 50% of the cases. The median of haemoglobin and platelet was 10.5 g/dL and 141,000/mm(3), respectively. After treatment, the evolution was good in all the cases, without relapse or any consequences. DISCUSSION/CONCLUSION: our study, in agreement with the national data, confirms the increase in the number of case of pediatric imported malaria, and underlines the mediocrity of the prevention, in particular in term of anti-malarial chemo-prophylaxis. These data, in a context of regular increase of international travels to endemic areas, suggest the necessity to improve the information of the general public, and the urgency of a better staff training of health care workers concerning malaria, in order to improve the prevention and the treatment of this potentially fatal disease.

Adolescent↗