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Biomedical subjects

P Forsell

Publications and source records attributed to P Forsell.

11 recordsLinked to original sources
PubMed1987

Transferability of a computer system for medical history taking and decision support in dyspepsia. A comparison of indicants for peptic ulcer disease.

The transferability of a British data base for differential diagnosis of dyspepsia using data obtained by computer interrogation was tested in 467 Swedish patients. The diagnostic value for peptic ulcer disease of symptoms such as frequent night pain relieved by food or antacids, smoking, family history of ulcer, food relief pain, male sex, and episodic pain was shown to be reproducible. However, for a number of symptoms their value for the diagnosis of peptic ulcer disease could not be reproduced in Swedish patients. The combined value of indicants was tested using a computer based algorithm for calculating diagnostic probabilities. The performance of this algorithm was poor when British data were applied to Swedish patients but reclassification of the Swedish patients on their own data base showed promising results. Crean and colleagues in Glasgow have developed a computer system for automated interrogation of patients with dyspepsia. The system utilises a large number of questions to obtain information regarding a maximum of 160 diagnostic indicants. The symptoms elicited from a patient can be compared with those of a large number of previously examined patients and the probabilities of ten different diagnoses can be calculated. The calculation of diagnostic probabilities is based on scores reflecting the diagnostic value of different symptoms in different diseases. After careful translation of questions the system has been transferred for use in Sweden. The present report is based on data from patients seen during the first two years with the system at a Swedish hospital.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗
PubMed1986

Perforating appendicitis. A nine-year survey of treatment and results.

This is a clinical study of 193 adult cases of perforating appendicitis during a nine-year period of treatment. There were 77 females (39.9%) and 116 males (60.1%) with ages of 15 years and above. Throughout the study period, the yearly perforation frequency ranged from 10.0 to 23.1% (mean 16.7%) of all cases with proven appendicitis. Perforation was equally common in both sexes, females: 15.5%, males: 17.6% of the appendicitis cases. In elderly patients (greater than or equal to 60 years of age) perforation was much more common; 37 out of 77 cases with proven appendicitis (48.1%). Compared to different ages (patients under and above 60 years of age), clinical and laboratory findings were found equal. Duration of symptoms showed no differences for younger and elderly patients. Preoperative delay in the hospital of at least 6 hours occurred in 39.9% of all patients, and was found equally common in patients younger than 60 years (39.1%) and in those from 60 years and older (43.2%). There were no fatalities in the study group. Postoperative septical complications predominated over non-septical (32.6 versus 9.3%), and were equally common in both sexes and in patients of different ages. The frequency of occurrence of septical complications was not significantly influenced by the duration of symptoms or by the duration of operation, furthermore, septical complications were equally frequent throughout the study period, although the use of antibiotics changed towards drugs more potent to cover anaerobic bacteria (28.1% infections for the period 1972-1976 versus 29.8% for the period 1977-1981).(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗
PubMed1986

Infertility in young women due to perforated appendicitis?

In a retrospective study the frequency of infertility was estimated in 41 women operated for perforated appendicitis from the catchment area of Huddinge University Hospital. As a control group we selected an identical number of females of the same age, social and national background. About 85% of the subjects in both groups answered the questionary. Excluding a large number of voluntarily childless women, there were 5 instances out of 20 (25%) in the patient group and 1 out of 24 (4.2%) in the control group of unvoluntary childlessness. We found the incidence of 25% of unvoluntary infertility in the perforation group noticeable, although statistically not significant.

Adolescent↗
PubMed1978

Antibiotic treatment of common bacterial respiratory tract infection in general practice.

Respiratory tract infections, particularly in children, are some of the most common conditions seen in general practice. It would seem reasonable, therefore, that these conditions would be treated well. However, analysis of the figures taken from the Australian Morbidity Survey conducted by The Royal Australian College of General Practitioners shows that whilst most general practitioners use antibiotics satisfactorily, there are a few occasions in which it is fairly obvious that there is a lack of knowledge of the action of a particular antibiotic against a specific organism. This article is not intended to be a treatise on the microbiology of different respiratory tract infections and antibiotic use, but it is intended to be a guide to the treatment of common respiratory infections as seen in general practice.

Anti-Bacterial Agents↗
PubMed1976

Streptococcal sore throat in general practice--a controlled study.

A controlled study was undertaken to determine the incidence of Group A haemolytic streptococci and other bacterial pathogens in throat swabs from patients presenting with sore throats. The isolation rate (38-8%) of Group A haemolytic streptococci from patients with acute tonsillitis was significantly higher than the isolation rate (8-9%) in a control group, but there was no significant difference in the isolation rates in patients diagnosed as having acute pharyngitis compared with the control group. There was no difference in the isolation rates of the other bacterial pathogens in the patient and control groups. In-vitro antibiotic studies were performed, and a comparison was made of the results of these tests and the treatment prescribed.

Acute Disease↗