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Biomedical subjects

P Forestieri

Publications and source records attributed to P Forestieri.

At least 37 records · Page 2Linked to original sources
PubMed1993

[Secondary bacterial peritonitis: a diagnostic and therapeutic update].

In spite of the availability of new powerful antibiotics, intraabdominal sepsis still has a high mortality rate (20-50%). With regards to postoperative peritonitis, the referred high mortality rate is due to a late recognition and a consequently late treatment. The causes for late diagnosis are: uncertain clinical picture; misuse of analgesic drugs; reluctance of the surgeon to accept a failure. Moreover, many operated patients are under treatment with antibiotics: their misuse, particularly broad spectrum ones, is responsible for the selection of resistant bacteria. Age is another very significant prognostic factor: mortality rate is constantly higher in elderly subjects than in younger ones. Malnutrition, immunodepression, origin and location of sepsis, concomitant diseases, immunosuppressive treatments, delayed diagnosis, all can significantly affect clinical outcome. Probably the most important and less assessable factor is represented by the surgeon himself with his experience and technical accuracy: any mistake may worse patient's prognosis. Recently, many Authors have stressed the pathogenic relevance of the intestinal mucosa as a barrier, which may influence the clinical course.

Acute Disease↗
PubMed1989

Carcinoma following gastric surgery: a national survey.

Definitive results of a national survey on the incidence of carcinoma following gastric surgery are reported. Data concern 8427 cases of surgically treated gastric cancer. 558 were affected by carcinoma following gastric surgery and 471 of them were operated on, representing 5.59% of all gastric cancers (8427) submitted to surgery. The statistical analysis of results has pointed out the need for a close follow-up program in patients over 50 years, operated on for benign gastroduodenal disease, especially 10 years postoperatively and in case of pre-cancerous lesions.

Aged↗
PubMed1984

First full blown syndrome of acute zinc deficiency in course of long term total parenteral nutrition: a clinical case.

The case of a surgical patient with a full blown syndrome of zinc deficiency is presented and the various implications related to a deficiency of this trace mineral are discussed. The symptomatology involved mental depression, visual disturbances, glucose intolerance, decreased serum alkaline phosphatase levels, wound healing impairment, eczematoid dermatitis and reduced humoral and cellular immune defences. Oral supplementation with zinc sulphate dramatically reversed the signs and symptoms of the syndrome and resulted in rapid wound healing. This case seems to have exhibited most of the different signs and symptoms reported from time to time in the literature. Awareness of zinc deficiency is being brought to light in many medical and surgical conditions. Total parenteral nutrition (T.P.N.) can exacerbate the lack of this trace metal and supplementation with fresh blood derivate are, as demonstrated, useless in these cases. Zinc, as component of various metalloenzymes, accounts for the clinical manifestations of its deficiency.

Alkaline Phosphatase↗
PubMed1984

Short bowel syndrome: clinical manifestations following extensive intestinal by-pass.

A personal experience with 43 cases of end-to-side jejunoileal bypass is reported. Two major clinical entities appear to emerge from the present study and in accordance with data from the literature: liver failure and the so-called enteric disease from bypass. Such observations were confirmed by the results obtained from an experimental investigation on 96 Wistar rats. The fact that the intestinal bacterial contamination seems to be the common cause of both effects and complications of intestinal bypass should limit by itself possible further developments of the procedure.

Diarrhea↗