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Biomedical subjects

P Follmann

Publications and source records attributed to P Follmann.

At least 19 recordsLinked to original sources

A clinical evaluation of XPERT NCT (Reichert) for glaucoma screening by optometrists.

XPERT NCT advanced logic pneumotonometer (Reichert) was studied for its reliability and use in glaucoma screening. The evaluated 2400 NCT measurements on 300 eyes were compared to the results of Goldmann applanation tonometry (GAT) from the same eyes. Repeated NCT tonometry had no significant effect on IOP. Local anesthesia reduced mean NCT-GAT difference and standard deviation significantly (p < 0.05), i.e. feeling due to the diminished air pulse force provided by the instrument had still considerable influence on IOP. NCT-GAT regression was significant (p < 0.01). Mean IOP readings provided by NCT were four mmHg higher than GAT values. Although accuracy was not satisfactory for exact measuring, it was satisfactory for screening. The results suggested that four mmHg less than the mean IOP value seen on the display is acceptable for screening when the difference between the minimal and maximal individual readings on the display is less than 2SD i.e. six mmHg. In the case of a greater difference, the maximal value is to be replaced, as NCT tends to read higher values than GAT.

Glaucoma

The effect of timolol, betaxolol and levobunolol on the surface of rabbit cornea.

Pigmented rabbits were treated with timolol maleate, betaxolol hydrochloride or levobunolol hydrochloride eye drops twice a day for six months. Animals of the same age group and breed were used as controls. There were no differences observed in corneal epithelium with light and transmission electron microscopy. With scanning electron microscopy, in the timolol and betaxolol treated animals the picture of the corneal surface was similar to that of normal rabbit corneas after exposure to air. In scanning electron micrographs of the levobunolol treated animals, the corneal surface resembled the corneas of normal rabbits treated with artificial tears.

Administration, Topical

[Treatment of senile maculopathy with etaretin].

The results of parenteral treatment with Etaretin in 40 patients (79 eyes) suffering from senile maculopathy are reported. In 84% of the cases there was a degeneration of the dry type and in 16% a disciform exudative maculopathy. The cases of dry maculopathy responded well within a floow-up period of 8 to 18 months.

Adult

Investigations into the aqueous humour dynamics in primary pigmentary degeneration of the retina.

40 patients with primary pigmentary degeneration of the retina were investigated for the possible coexistence with glaucoma. 12.5% established primary glaucoma cases and 7.5% suspicious glaucoma cases were found. In primary pigmentary degeneration of the retina with no glaucoma the intraocular pressure and the parameters of Leydhecker's test showed the same distribution as that of the controls selected at random. The intraocular pressure and the tonographic parameters except for CL3-7 were slightly lower on the average in the group with retinitis pigmentosa than in the controls.

Adolescent

Dynamography.

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Blood Pressure