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Biomedical subjects

P Flandroy

Publications and source records attributed to P Flandroy.

43 records · Page 3Linked to original sources

Treatment of mandibular arteriovenous malformations by direct transosseous puncture: report of two cases.

Mandibular arteriovenous malformation (AVM) is a potentially life-threatening pathology requiring radical treatment. We report two female patients, aged 14 and 16 years, in whom occlusion of the AVM with Ethibloc after percutaneous transosseous puncture achieved definitive recovery. The first case was treated by direct injection of Ethibloc following inefficient arterial embolization with Ivalon particles. In the second case, Ethibloc was injected without previous arterial embolization. Control examinations performed at 6 months and 2 years confirmed complete calcification of the mandible in the first case and a total obliteration of the AVM on angiography in the second case.

Adolescent↗

Probable trigeminal nerve schwannoma in a dog.

A 7-year-old male Husky dog developed atrophy of the right masseter muscle and pruritus of the right side of the face. A myogenic origin was excluded using muscular biopsy. Electrophysiologically, there was involvement of the motor and sensory fibers of the trigeminal nerve, suggesting a lesion located between the brainstem and the trigeminal ganglion. On MRI examination, a nodular mass was detected in the right caudal fossa. This mass was characterized by intense enhancement after injection of contrast medium. Because of the progressive clinical signs, electrophysiology, and MRI results, a presumptive diagnosis of a trigeminal nerve schwannoma was made. The animal's condition improved slightly with corticosteroids. The dog underwent euthanasia 3 months after initial presentation. Necropsy was not performed.

Animals↗

[Low flow venous malformations in children].

Low flow venous malformations in children are a diagnostic and therapeutic challenge. They are present at birth but may not be evident; they have a commensurate growth. They are pure or combined (capillary or lymphatic-venous). At examination, one observed soft, compressible bluish swellings; there is no thrill or bruit. They are slow flow anomalies with venous stasis which may induce thrombosis or localized consumptive coagulopathy. Skeletal distortion or bony hypertrophy or hypoplasia may also be observed; histological examination of surgical specimen reveals infiltration of adjacent structures (skin, bone, muscle); ultrasonography and duplex-Doppler may be helpful in differentiating the venous malformation from lymphatic or arteriovenous anomalies. Diagnosis from hemangioma will be obtained by magnetic resonance imaging; this last investigation will also provide informations on the infiltration of the adjacent tissues by the pathologic process. Standard X ray may show phleboliths of skeletal distortion. Most of venous malformations are asymptomatic and treatment consists in reassuring the child and in giving advice to the parents to prevent trauma to the lesion. Conservative treatment must be advocated (compression garments, prevention of thrombosis with salicylates) since total excision of venous malformation is illusory and postoperative morbidity may be important. Surgical excision of limited cumbersome malformations may be indicated; sclerotherapy of the lesion with Ethibloc makes surgery easier.

Arteriovenous Malformations↗

[Chemonucleolysis. A therapeutic alternative in extra-canalicular lumbar disk hernias].

Between 1% and 13% of lumbar disk hernias lie in a very lateral position outside the canal. Diagnosis of the disease is based mainly on CT scan with x-ray. Once conservative therapy has failed, surgery has hitherto been the only treatment proposed, but this generally requires sacrifice of an articular mass. The authors report their experience with chemonucleolysis with chymopapain in five patients presenting this type of hernia. Cure was obtained in four cases. The main advantage of the technique is that osteo-articular structures are preserved.

Aged↗

[Incidence and treatment of subdural hygroma in severe head injuries].

In a population of 109 subjects with severe head injury (Liège score less than or equal to 12) we observed secondary development of subdural hygroma in sixteen patients. These liquefying processes were mostly secondary to the entry of CSF in the subdural space from tears in the arachnoid. Half the accumulations were accompanied by increased subdural pressure. Drainage of the subdural fluid brought clinical improvement in patients with elevated subdural pressure (greater than 15 torr).

Adolescent↗