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Biomedical subjects

P Firt

Publications and source records attributed to P Firt.

At least 73 records · Page 4Linked to original sources

Haemodynamic changes immediately following myocardial revascularization.

The haemodynamic values before and immediately after direct myocardial revascularization were compared in 14 patients with ischaemic heart disease. Within the first hours after surgery cardiac output decreased to 50% of the preoperative value owing to a decrease in stroke volume, wedge pressure was increased, and systemic pressure was maintained at preoperative values by a rise in peripheral resistance. After the initial decrease cardiac output again increased to preoperative values (after 7 h) and above these values (19 h after surgery). Systemic blood pressure decreased owing to rapidly decreasing peripheral resistance. Knowledge of the pattern of haemodynamics in the early postoperative period facilitates the diagnosis of untoward circulatory episodes and permits to distinguish the effect of therapy from the haemodynamic changes normally occurring during this period.

Blood Pressure↗

[Emergency coronary surgery].

The authors report their experience with combined investigation and surgical treatment of patients with threatened myocardial infarction and those with postinfarction rupture of the interventricular septum. Direct reconstruction of coronary arteries was performed in 12 of 17 patients with threatened myocardial infarction (three patients died, two of cardiac complications). In the survivors, anginal signs either disappeared or became less pronounced. The correction of interventricular septum rupture was performed in 8 patients, three of whom died. The remaining five patients showed obvious improvement.

Adult↗

The effect of renal revascularization on decreased glomerular filtration rate in patients with renovascular hypertension.

The effect of revascularization on decreased glomerular filtration rate (GFR) was studied in 18 patients with renovascular hypertension (RVH) for a period of 5 to 74 months after operation. Renal artery stenosis (SRA) was present unilaterally in 3 patients, bilaterally in 13 patients, and in two patients with one kidney. Following surgical correction, the GFR increased or normalized in 6 patients, decreased in 2, and did not change in 10 patients. The blood pressure of almost 90% of the operated patients normalized or improved. The results support the assumption that severe hypertension is indicated for surgery, irrespective of the magnitude of GFR decrease. Revascularization effected a reversal of renal insufficiency only in a third of the patients.

Adult↗

Character of mitral valve flow in left atrial tumor.

The pulsed Doppler echocardiography (PDE) was used to evaluate the character of mitral valve flow in a large atrial tumor. The tumor obstructed the mitral orifice during diastole. PDE findings, however, showed normal triphasic diastolic flow within the actual mitral orifice and no changes typical for mitral stenosis. The same turbulence pattern as in mitral stenosis was detected in the left ventricle. In addition, PDE revealed the presence of mild mitral regurgitation in agreement with angiography.

Aged↗

Contribution to the treatment of post-infarction cardiac aneurysms.

The authors discuss contemporary problems of resection of post-infarction cardiac aneurysms. In their opinion the main cause of left-sided cardiac failure is enlargement of the left ventricle which leads to increaser demands on the tension of muscle fibres and work of the heart. These mechanisms potentiate at the same time the ischaemia of the heart muscle. Reduction of the left ventricle by appropriate resection eliminates or improves markedly this adverse condition in particular when there is an opportunity of simultaneous revascularization by an aorto-coronary by-pass. Based on the results in a series of 52 operations the authors consider assessment of the stroke volume before and after the foreseen resection a suitable and reliable criterion for indication of the operation. Its application led to a substantial decline of the surgical mortality caused in particular by the postoperative low cardiac output syndrome.

Heart Aneurysm↗

Indications for surgical treatment of occlusive disease of the afferent cerebral arteries.

Indications for reconstruction operations in the region of branches of the arch of the aorta must be based on a comprehensive evaluation of the neurological and angiographic finding and the general condition of the patient. This ensues from the experience assembled in more than 800 operations performed since 1959. To evaluate the surgical risk, a scoring system was elaborated which evaluates the partial risks of each basic aspect of indication. Based on the sum of partial risks, four grades were defined. Patients who meet the prerequisites for surgical risk I and II (mainly with transient ischaemic attacks and asymptomatic stenoses of the internal carotid artery) can be indicated, with regard to hitherto assembled results, unequivocally for reconstructions. In grade IV risk it is essential to consider whether the risk of the natural course is greater than the risk of the operation and whether the affection of the afferent cerebral artery is the main limiting factor. The authors discuss contemporary views on indications of acute reconstructions of stenoses and occlusions of the internal carotid artery based on the neurological and angiographic factor and the time factor. From the evaluation of results of 92 urgent operations on account of recent or imminent symptoms of cerebral ischaemia ensues that for the result the grade and dynamics of the ischaemic cerebral affection at the time of the operation are decisive.

Arteriosclerosis↗