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Biomedical subjects

P Ficat

Publications and source records attributed to P Ficat.

At least 37 records · Page 2Linked to original sources

[Etiopathogenesis of arthrosis; nosological consequences].

A nosological classification of arthrosis is proposed, consisting of two groups depending on whether the cartilage is intact (mechanical chondrosis) or altered (structural chondrosis). For both categories the principal aetiologies are mentioned. This aetiological differentiation has the aim of counteracting the facile diagnosis of primary arthrosis and is based on more elaborate diagnostic methods concerning the condition of the bone and cartilage.

Cartilage Diseases↗

[Osteochondritis dissecans and osteonecrosis of the lower end of the femur. Value of bone marrow functional exploration].

The authors report the results of 19 functional investigations carried out for osteochondritis in 11 cases, and osteonecrosis of the knee in 8 cases. The 8 cases of osteonecrosis all had hemodynamic disorders with increased pressure in the bone marrow and stasis due to circulatory obstruction. On the other hand, 5 cases of osteochondritis out of the 11 explored had no disturbance of marrow blood supply. However, of the 6 cases of osteochondritis with vascular disorders, there were 5 who had some other reason which might explain the disorder blood supply within the bone. It thus seems that one may contrast two types of disease: -One, characterized by an intra-osseous circulatory disorder for which one might reserve the terms osteonecrosis, which occurs in patients aged over 60 years, but which may be observed in juvenile forms. - The other, characterised by the absence of any hemodynamic disturbance and in which the foreign body seems to result from a very localised disorder which does not affect the bone marrow blood supply. One may use here the term, osteochondritis. We propose to substitute this physiopathological classification for the classical division based on age and on X-rays. Investigation of the blood supply of the bone, permits, as with strontium, early diagnosis at a pre-radiological stage.

Adolescent↗

Arthrosis: new diagnostic procedures.

The authors emphasize two new methods for determining the real state of the cartilage and bone structure. These methods permit the early diagnosis of arthrosis and necrosis before X-ray changes appear and perhaps a better management and prognosis.

Biopsy↗

[Necrosis and ischemia of the femoral head during arteritis of the lower extremities. Survey of 138 patients with arteritis and 159 aortographies].

Among 138 subjects suffering form arteritis of the lower limbs, the authors found clinical signs of lesions in one or both hips in 47.6 percent of cases and radiological signs in one or both hips in 42.8 percent of cases. Five patients presented a distinct flattening of the femoral head indicating necrosis at stage III, 19 showed voluminous or multiple dense islets in the femoral collar or head indicating necrotic lesions at stage II, and 26 showed narrowing of the superior joint space mostly on the internal side. The authors think ihat the latter sign indicates ischaemic chondropathy. Eleven of the 138 patients had undergone pertrochanteric phlebography : this was abnormal in all 11 cases. At the same time the authors studied the coxofemorals on 159 aortograms and found, among other anomalies, 2 cases of advanced necrosis at the stage of rupture (stage III). This study tends to confirm the occurrence of necrotic lesions of the femur that are secondary to arteriopathies.

Adult↗

[Progress in diagnosis in osteo-articular pathology (author's transl)].

Osteo-articular diagnosis is too often considered at present to be synonymous with radiological diagnosis. This has come to be almost a sine qua non. Nevertheless a normal X-ray does not mean that the patient is free of disease. On the contrary, there exists the considerable handicap of the latent period between the onset of disease and the appearance of radiological signs. If blind faith in such a notion is allowed to persist, a profitable means of progress is closed both to our discipline and pathology in general. Over the last decade has emerged a new tendency towards the study of the initial phases of disease and an earlier diagnosis during the pre-radiological phase. This tendency, which opens new perspectives, already enjoys highly promising success and deserves wider recognition, encouragement, development and study. It results more from an attitude of mind rather than the development of a technique and for this reason should lead to the suggestion of other methods and solutions. In bringing us closer to the source of the pathological process it will aid in better understanding of its true nature and pathogenesis. In a word, it will help us to understand the starting phases of disease whilst radiology reveals only the active process. Inasmuch as early physiopathological processes are reversible, it should open the door to new therapeutic approaches.

Bone Diseases↗

[Surgical repair of chronic instabilities of the cruciate ligaments of the knee].

The authors have developped a technique aiming at replacing the anterior cruciate ligament by the tendon of gracilis muscle derouted through the intercondylar region and acting as an active transplant in 32 cases. In 20 other cases replacement of the posterior cruciate ligament was obtained by the use of the tendon of semi tendinosus muscle acting as a passive neo-ligament. The follow-up study demonstrated 87 p. 100 of good results after isolated tears of the anterior ligament and 83 p. 100 after isolated tears of the posterior ligament. 21 times an additional plasty of the medial ligament had to be performed. In these combined lesions results were less favourable.

Elasticity↗