[Count of cross-infection bacteria in the Limoges Resuscitation Service (Study of 2 years of operation)].
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Biomedical subjects
Publications and source records attributed to P Feiss.
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The authors compare the effects of either 0,5 or one milligram of intrathecally injected morphine on the post-operative course of 45 patients scheduled for transvesical prostatectomy. The patients were randomly assigned to three groups. Group A patients served as reference and were anesthetized by intrathecal injection of prilocaine 100 mg. Group B and C patients underwent the same anaesthetic procedure but prilocaine was injected simultaneously with either 0,5 (B) or one milligram (C) of morphine. Group A patients experienced postoperative pain for eighteen hours and requiring a mean subcutaneous dose of 20 mg of morphine. B and C patients had a satisfactory degree of analgesia. Nevertheless, there was a statistically significant difference of analgesia scores between groups C and B. The group C patients remained free of respiratory impairment. One mg of intrathecal morphine seems optimal for analgesia after prostatectomy.
The purpose of this study was the comparison of the effects on the labor and neonates of epidural analgesia conducted either with bupivacaine or 2-chloroprocaine. Hundred and three parturients were included in the study. They were randomly divided in two groups. Sixty-three patients received bupivacaine in 0.25% solution and 40 received 2-chloroprocaine in 2% solution. Epinephrine was not added to local anesthetics. The first dose was 25 mg of bupivacaine (10 ml) or 200 mg of 2-chloroprocaine (10 ml). Reinjections occurred every 30 min for 2-chloroprocaine (80 mg) and every hour for bupivacaine (10 mg). The time of onset of cutaneous analgesia was similar in both bupivacaine (12.5 +/- 4.7 min) and 2-chloroprocaine (13.8 +/- 5.1 min) patients. The incidence of incomplete or insufficient analgesia was significantly higher with 2-chloroprocaine. The number of parturients who required forceps for conclusion of childbirth was not statistically different with bupivacaine (n = 25, 40%) or 2-chloroprocaine (n = 11, 28%) (CHI2 = 1.5971, p = 0.2063). The second stage of labour was significantly longer in parturients who required forceps extraction in both groups. These patients also received significantly more local anesthetics. All newborns had an Apgar score performed before the third minute following birth. All observed Apgar scores except one of bupivacaine group were over eight. Umbilical cord blood was drawn for pH determination. Cord blood pH was slightly but significantly lower in bupivacaine (7.314 +/- 0.106) than in 2-chloroprocaine (7.345 +/- 0.06) patients (t = 1.6968, p = 0.046). Newborns extracted with forceps after maternal bupivacaine epidural analgesia had a significantly lower umbilical blood pH (7.278 +/- 0.117) than newborns who did not required forceps in the bupivacaine group (7.337 +/- 0.093) (t = 2.1986, p = 0.0159).(ABSTRACT TRUNCATED AT 250 WORDS)
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