Toxic hepatitis due to benzo-pyrone.
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Biomedical subjects
Publications and source records attributed to P Faurschou.
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Granulocytes with cytoplasmic inclusions (RA = Rheumatoid Arthritis cells) have previously been found in pleural effusions of rheumatoid and tuberculous origin. We now report the finding of RA-cells in effusions from patients suffering from bronchogenic carcinomas of the squamous-cell type and malignant mesothelioma. Such cells occurred only rarely in other types of primary or secondary lung tumour.
The fine structure of neutrophil granulocytes from pleural fluid obtained from patients with rheumatoid or tuberculous pleuritis or epidermoid carcinoma of the lung was identical irrespective of the primary disease of these patients. Homogenously stained lipid-like inclusions were present in the cytoplasm of the neutrophil granulocytes. They seemed to be formed de novo, as they lacked a distinct limiting unit membrane. The fine structure of the lipid-like inclusions gave no evidence to support the presence of immune complexes, these were probably located in the quantitative much fewer phagosomes of the granulocytes.
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