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Biomedical subjects

P Faul

Publications and source records attributed to P Faul.

At least 37 records · Page 2Linked to original sources
PubMed1982

[Critical observations on the current diagnostic value of prostate cytology].

Based on an inquiry it was found that aspiration biopsy and cytology of the prostate in West-Germany is practiced less than in Scandinavia. This in spite of the fact that the fine needle biopsy can be done with the same accuracy as punch biopsy of the prostate, but with more advantages. Beside of that the cytological grading proofed to be very important for the biological activity of the carcinoma of the prostate. The technique of fine needle biopsy of the prostate is not easy and must be practiced very well.

Biopsy, Needle↗
PubMed1981

[Use of dopamin (hydroxytyramine) in urosepsis of septic shock (author's transl)].

Gram negative sepsis is still a very serious disease with a very high mortality. The effect of Hydroxytyramine was tested in ten patients with urosepsis. Hydroxytyramine had a specific beneficial on the renal function during shock and eight of ten patients with severe urosepsis survived. The additional use of hydroxytyramine in the treatment of urosepsis seems to improve the prognosis of this life threatening condition.

Aged↗
PubMed1980

[Urethrotomia interna: clinical importance of internal urethrotomy in recurrent cystourethritis and irritable bladder in women (author's transl)].

The present results show that operative dilatation of the female urethra in recurrent bladder complaints and demonstrable obstruction is a very promising form of treatment which can be carried out by every practising urologist with anesthetic availability. Failures must be accepted, because at all events one question remains unanswered: why one patient can be helped by the treatment whereas in another the complaints persist.

Cystitis↗
PubMed1980

[Transrectal aspiration biopsy of the prostate].

Transrectal aspiration biopsy and cytologic examination are reliable methods to diagnose a carcinoma of the prostate. However, it is not widely used in other than Scandinavian countries. The reason for this is the difficulty of using a correct biopsy technique and a good preparation of the smear. The technique is not as easy as one may think and must be taught carefully. The diagnostic accuracy depends mostly on the clinician who performs the needling, less on the cytopathologist. Cytological grading is a valuable indicator for the biological activity of a carcinoma of the prostate. Cytological follow-up of a treated carcinoma gives important information about the effectiveness of therapy.

Biopsy, Needle↗
PubMed1980

Prognostic significance of cytological differentiation grading in estrogen-treated prostatic carcinoma diagnosed by fine-needle aspiration biopsy. (Five-year follow-up of 496 patients).

The value of fine-needle aspiration biopsy of carcinoma of the prostate and its cytological grading is demonstrated. The grade of morphological differentiation in cytological smears has proved to be a reliable criterion for the prognosis in 496 estrogen-treated prostatic carcinoma patients. The life expectancy of low-differentiated and anaplastic cancer patients undergoing treatment is so poor that the justification for antiandrogen treatment in this group of carcinomas appears extremely doubtful. For this reason, the degree of differentiation of the tumor should be considered when undertaking therapeutic measures in view of its relevance for the prognosis.

Adult↗
PubMed1980

[Clinical significance of prostate cytology].

The transrectal fine-needle biopsy and the cytological examination of the prostate is a method which is of the same value as the punch biopsy and the histological examination. A carcinoma of the prostate is also to be diagnosed cytologically reliable. The morphological division in several degrees of differentiation--grading--is possible. By grading the biological activity of the carcinoma and thus also the clinical course of the disease is determined as far as possible. Cytological controls of the course under treatment given the possibility to objectify the success of therapy better, from which may result important consequences for the treatment.

Biopsy, Needle↗
PubMed1979

[Diagnostic possibilities of the prostate cytology, particularly considering the influence of the cytological degree of differentiation with the prostate carcinoma upon the 5 year survival rate (author's transl)].

Today, the transrectal fine-needle biopsy is firmly integrated in the establishment of the diagnosis of prostate carcinoma within the prophylactic examinations and as a check-up examination during the treatment of prostate carcinoma. Cytologically, the prostate carcinoma may be divided into four different degrees of malignancy: high-grade, medium-grade, low-differentiated and anaplastic carcinoma. Differential-diagnostically, chronic prostatitis may raise certain problems both clinically and cytologically. Electronmicroscopic examinations of samples taken by fine-needle biopsy are possible. Certain changes under anti-androgen treatment are examined at present. Under the contra-sexual treatment of the prostate carcinoma carrier there occur changes of the normal and carcinoma cells the extent of which permits conclusions as to the therapeutic hormone effect. This, in turn, results in consequences for the respective treatment. In 496 prostate carcinomata cytologically diagnosed since March 1970 the author was able to demonstrate that the 5 years' survival rate is determined by the cytological degree of differentiation. Whereas highly and medium-differentiated prostate carcinomata show an average 5 years' survival rate of 62.5 per cent, this amounts only to 33.9 per cent with the low-differentiated and anaplastic prostate carcinomata. The total 5 years' survival rate of all cytologically diagnosed carcinomata came up to 46.8 per cent. The 1-, 2-, 3-, 4- and 5 years' survival rate of all cytologically diagnosed prostate carcinoma carriers is almost in conformity with the values found by Esposti. The degree cytological differentiation in connection with the clinical stage clearly determines the clinical course with our patients.

Biopsy, Needle↗
PubMed1978

[X-ray-video amplifier photography: use in urologie X-ray diagnosis and renovasography (author's transl)].

Our experiences indicate that the 'urograph', in combination with the 100-mm sheet-film camera, represents an x-ray apparatus that is just about optimally suited to the needs of urologic x-ray diagnoses. Only in extreme situations is the range of movement of the tabletop in the direction of the head and feet insufficient. A major advantage of the camera, and the one which, above all, plays a decisive role in the urologic x-ray diagnosis of children, is that the amount of radiation can be reduced by about 1/2 to 1/3 that necessary with conventional photo techniques. Through optimal use of the apparatus, considerable time and personnel can be saved. In view of the additional fact that kidney angiographs can be performed with this apparatus, in combination with the 100-mm camera, with minimal problems, minimal time, and minimal stress for the patient, x-ray-video amplifier photography represents an important addition to urologic x-ray examination possibilities that today we can no longer afford to do without.

Angiography↗
PubMed1978

[The prognostic significance of cytologic differentiation grades of estrogen-treated prostata carcinoma. Progress control of 496 prostate carcinoma patients treated with estrogen for five years (author's transl)].

The morphologic differentiation grade of cytologic smear preparations proved to be a reliable gradation measurement for the prognosis of 496 patients suffering from prostate cancer and treated with estrogen. Compared with that of other cancer patients, the life expectancy of low-differentiated and anaplastic cancer patients undergoing estrogen treatment is so poor that the rationale of using antiandrogenous treatment in this carcinoma group seems extremely questionable to us. This is why, in view of the predictable prognosis, the differentiation grade of the tumor should be considered when undertaking therapeutic measures.

Adult↗
PubMed1975

[Coagulation disorders in prostatic carcinoma (author's transl)].

70 nonselcted patients with prostatic carcinoma underwent coagulation analysis. Sxi had typical evidence of diffuse intravascular coagulation and in 8 cases such a disorder was highly probable. In 3 patients coagulation alterations appeared only after estrogen treatment, 17 patients (24.3%) thus showed evidence of intravascular coagulation. The hemostatic distrubance was silent in all but 3 cases where bleeding occurred. Coagulation disorders were found mainly in advanced stages and poorly differentiated carcinomas. There was a much higher content of thromboplastic activity in prostatic carcinoma than in normal prostatic tissue. Heparin plays a predominant role in the treatment of the coagulation disorder. In addition to therapy of clinically maifest consuption coagulopathy heparin can be used in prophylaxis against bleeding and thrombosis in cases with clinically silent intravascular coagulation and also in estrogen treatment.

Aged↗