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Biomedical subjects

P F Van Peenen

Publications and source records attributed to P F Van Peenen.

At least 19 recordsLinked to original sources

Mortality in a recent oil refinery cohort.

A retrospective cohort mortality study of 10,763 Amoco Corporation oil refinery workers employed between 1970 and 1980 showed low overall mortality; the standardized mortality ratio for all causes of death was 73 for white males and 68 for black males. White male mortality was examined by several exposure classifications devised for group cohort members by potential for exposure to refinery processes and exposure to two components of petroleum (light aromatic hydrocarbons and heavy oils). Statistically significant elevations were found in various exposure groups for skin cancers, digestive system cancers, and benign neoplasms. Of these, skin cancer mortality appeared to increase with increasing exposure.

Environmental Exposure↗

Health insurance claims of petrochemical company employees.

This paper describes a morbidity data base for epidemiologic studies which uses information from health insurance claims. Strengths of the data base include completeness and relatively low cost. A limitation is the length of time needed for all claims to be received and processed: rates generated using current information are lower than they will be after all claims are processed. Nevertheless, internal comparisons can presently be made using such rates. Examples illustrate differences in claims experience according to employees' smoking habits and according to kind of job.

Adult↗

Determining exposure categories for a refinery retrospective cohort mortality study.

This paper describes and compares two methods used to assign exposure categories to 10,766 petroleum refinery employees included in an epidemiological study. The first scheme grouped individuals into six organization (OR) job groups: Administrative, Maintenance, Operations, Laboratory, General and Other. This scheme used "most common administrative department," as determined by computerized job histories. For the second classification scheme, "most common job title" and "most common plant location" were used to group individuals in four ways (IH codes): 1)job type (administrative, maintenance, operations and unknown); 2) contact with refinery processes; 3) exposure to light aromatics; and 4) exposure to heavy oils. Exposure categories for the latter three were none, occasional, routine and unknown. Comparison of the two schemes showed that OR job groups developed from administrative job histories were sometimes useful in classifying employees according to refinery exposures. While OR job groups were acceptable for employees clearly in managerial, maintenance or operations positions, IH codes provided more precise exposure profiles for these three relatively homogeneous groups. For individuals in laboratory positions and those with vague or unspecified department codes (23% of this cohort), the IH classification codes were necessary to group employees by job and exposure.

Humans↗

Smoking habits of oil refinery employees.

Smoking habits of White male employees of a large oil company were analyzed. There were only slight differences in smoking habits between refinery and nonrefinery employees. Salaried employees, both at refineries and elsewhere, smoked much less than hourly employees.

Adult↗

Quetelet index.

Explore the source record for details and available documents.

Names↗

Survey of reproductive events of wives of employees exposed to chlorinated dioxins.

To determine whether paternal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) or other polychlorinated dioxins might be associated with adverse pregnancy outcomes, an interviewer-administered questionnaire survey was conducted among wives of Dow Michigan Division employees in the Midland, Michigan, area who had been potentially exposed to dioxins. A control group consisted of wives of employees who had no dioxins exposure and whose hire dates were comparable to those of the men in the exposed group. A total of 737 conceptions, which resulted in 637 live births and 10 stillbirths and spontaneous abortions, were identified as having paternal exposure; 2031 conceptions, resulting in 1785 live births and 246 stillbirths and spontaneous abortions, were identified as having no paternal exposure to any isomer of dioxin. Odds ratios were calculated for dependent variables consisting of spontaneous abortions, stillbirths, infant deaths and several categories of congenital malformations. Trend analysis was performed for duration-of-paternal-exposure of 12 months or less, or more than 12 months. Overall, no statistically significant associations were found between any exposure and pregnancy outcome, either before or after stratification by pertinent sets of up to nine covariables.

Abnormalities, Drug-Induced↗

Human parasitoses of the Malili area, South Sulawesi (Celebes) province, Indonesia.

A biomedical survey was conducted in 9 villages in the Malili area of South Sulawesi, Indonesia. Blood specimens were examined for malaria and microfilariae; stool specimens were examined for intestinal parasites. Malaria parasitemias were rare; Plasmodium falciparum was detected in 10 and P. vivax in 11 of 985 blood smears. Malayan filariasis was endemic to all villages surveyed. The overall prevalence of detectable microfilaremias was 15%, varying from 34% in Kawata to 1% in Nuha. Microfilarial densities, expressed as MfD50 averaged 8.0 and varied from 1.1 in Timampu to 16.0 in Karabbe. Intestinal parasites were common. Although Schistosoma japonicum was not found, 97% of the examined had one or more intestinal parasites as follows: Ascaris lumbricoides (74%), Trichuris trichiura (65%), hookworm (62%), Entamoeba coli (38%), Endolimax nana (10%), Entamoeba histolytica (6%), Iodamoeba bütschlii (4%), Entamoeba hartmanni (3%), Giardia lamblia (2%) Chilomastix mesnili (1%) and Enterobius vermicularis (1%). Strongyloides stercoralis larvae and Hymenolepis nana eggs were detected once each and heterophyid-like eggs were detected twice.

Adolescent↗