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Biomedical subjects

P F Sheedy

Publications and source records attributed to P F Sheedy.

At least 127 records · Page 7Linked to original sources

Comparison of whole lung tomography and computed tomography for detecting pulmonary nodules.

Detecting pulmonary metastasis is important when planning surgical therapy, radiotherapy, or chemotherapy in patients with known malignancy. A series of 91 patients was studied by both whole lung tomography and computed tomography (CT) of the lungs. More pulmonary nodules were detected with CT than with whole lung tomography in 32 (35%) of the patients. Of the 91 patients in the study, 31 had resection of some or all of the pulmonary nodules. In 27 patients, the nodules were primary or metastatic malignant lesions. Bilateral pulmonary nodules were detected with CT in 13 patients when whole lung tomography had demonstrated nodules in only one lung. CT has replaced whole lung tomography as the method preferred by the authors for detecting pulmonary nodules in selected patients at risk to develop pulmonary metastasis.

Adolescent↗

Results of reoperation for hyperparathyroidism, with evaluation of preoperative localization studies.

During the past 3 years (June, 1974, to July, 1977), 51 patients underwent reoperation for persistent or recurrent hyperparathyroidism at the Mayo Clinica. The overall success rate for cervical reoperation was 72% and for mediastinal reoperation, was 64%. Arteriography alone provided accurate preoperative localization of missing parathyroid tumors in 11 of 17 patients at a cost per patient benefited of approximately $1,700. Selective thyroid venous sampling with parathormone assay alone correctly lateralized hyperfunctioning glands in only four of nine patients at a cost per patient benefited of approximately $1,900. When used in combination, these studies provided correct localization or lateralization of parathyroid tumors in five of seven patients at a cost per patient benefited of approximately $2,000. Three patients experienced significant neurological complications as a result of thyrocervical arteriography. There were no complications due to venous sampling. In patients who has undergone a less than thorough initial explorations due to venous sampling. In patients who had undergone a less than thorough initial exploration of the neck, the success rate for reoperation was not enhanced by obtaining preoperative tumor localization studies. However, in those patients who had had a thorough and systematic exploration of the neck at their first operations, the success rate for reoperation was almost doubled when preoperative arteriography or venous sampling (or both) was employed.

Adenoma↗

Body computed tomography: a clinically important and efficacious radiologic procedure.

In the institutions represented by the authors, more than 7,500 body CT examinations have been performed. Body CT has been found to be particularly useful in solving specific problems, especially when other diagnostic procedures yield confusiing results. Radiologists and their collegues, and not governmental agencies and insurance companies, should define the experimental, research and clinical usefulness of computed tomography.

Humans↗

Computed tomography in the evaluation of patients with suspected carcinoma of the pancreas.

The authors assess the efficacy of CT of the pancreas in a series of 151 patients with suspected pancreatic carcinoma. CT diagnoses were divided into four categories based on the original interpretation: "mass" or carcinoma (53 scans); normal pancreas (68 scans); normal pancreas, but another pathologic process was discovered on the CT scan (20 scans); and unsatisfactory or indeterminate examinations (10 scans). In more than 50% of the erroneous diagnoses of pancreatic carcinoma, the mass lesion seen on CT was found at surgery or angiography to be adjacent to, not arising from, the pancreas. False-positive interpretation can be avoided by improved equipment and technique and the accumulation of interpreter experience.

Adenocarcinoma↗

Computed tomography of the liver.

The diagnostic value of computed tomography (CT) of the liver depends on proper conduct of the examination, knowledgeable interpretation of findings, and an appreciation of the capabilities and limitations of the method. This report documents 10 months of experience with abdominal CT in more than 600 liver examinations using a system fast enough to eliminate respiratory motion. This experience supplied data on the CT appearance of the normal liver and its variations and of various hepatic abnormalities, on the conduct of the examination, including the appropriate of contrast material, and on some of the problems that reduce the technical quality of the examination. CT was highly accurate, but not infallible, in detecting and defining space-occupying lesions and in detecting fatty infiltration; it was less helpful in detecting diffuse hepatic disease. In bile duct obstruction, CT displayed not only the dilated ducts but often the obstructing lesion.

Biliary Tract Diseases↗

Retrospective comparison of radionuclide scans and computed tomography of the liver and pancreas.

Computed tomography (CT) and radionuclide examinations of the liver and pancreas in 50 patients were compared retrospectively to evaluate their value as diagnostic tests. CT was superior to 75Se-selenomethionine in evaluating pancreatic disease. Both 99mTc-sulfur colloid scans and CT scans were sensitive detectors of liver masses; however, there were more false positive 99mTc-sulfur colloid scans (16% compared to 4%). CT was superior in detecting biliary obstruction and ascites, in assessing diseases that involved the liver extrinsically, and in evaluating the status of adjacent organs. 99mTc-sulfur colloid scans were more sensitive in detection of diffuse non-neoplastic liver diseases (cirrhosis, hepatitis, and cholangitis). Simultaneous interpretation of CT and radionuclide scans was often more helpful than independent interpretation, and the two techniques are therefore complementary.

Gallium Radioisotopes↗

Diagnosis and evaluation of retroperitoneal tumors by computed tomography.

Nineteen patients with primary and recurrent retroperitoneal tumors were examined by computed tomography. Correlation between CT and subsequent operative findings was remarkably accurate. CT provided clinically useful information regarding the presence, size, extent, and composition of the tumors and also their effect on adjacent structures. CT is recommended for any patient suspected to have a primary or recurrent retroperitoneal tumor.

Adolescent↗

Computed tomography of the retroperitoneal space.

Computed body tomography is an easily accomplished method that precisely displays the normal and pathologic anatomy of the retroperitoneal space. Suspected retroperitoneal disorders, which are often clinically confusing or obscure, can now be detected or excluded with remarkable accuracy. Few innovations in radiology have more effectively fulfilled such a conspicuous need.

Abscess↗

Performance evaluation and quality assurance of computed tomography scanners, with illustrations from the EMI, ACTA, and Delta scanners.

Performance evaluation of equipment for computed tomography (CT) involves the integration of: (a) establishing performance criteria; (b) designing and implementing test procedures; and (c) reconciling test results in terms of desired performance. Precision (noise), contrast scale, linearity, accuracy, spatial independence, spatial resolution, artifacts, reproducible performance, and patient exposure are several parameters discussed, as are problems of measurement with regard to non-water bath scanners. Performance and quality control tests for the ACTA, Delta, and EMI scanners are outlined. Guidance for the prospective purchaser of CT equipment is presented as a summary of the ideas discussed.

Computers↗

Computed tomography of the body: initial clinical trial with the EMI prototype.

A review of the first 400 cases examined on one of three prototype EMI body scanners is presented. During the initial evaluation phases, it became obvious that computed tomography of the body has tremendous potential in the evaluation of various organs and disease states. The technique has been most useful in evaluating patients with known or suspected abdominal neoplasm, particularly lesions of liver, pancreas, retroperitoneum, and kidney. Too few cases have been studied to realistically quantitate its impact on the total field of medical diagnostic imaging.

Abdominal Neoplasms↗

Initial clinical experience with computerized tomography of the body.

Computerized tomography of the body, now possible with an instrument that can complete a scan rapidly enough to permit patients to suspend respiration, adds an important new dimension to radiologic diagnosis. Cross-sectional antomy is uniquely reconstructed to provide accurate diagnostic information for various disorders throughout the body.

Ascites↗

Omental arteriovenous fistula following liver biopsy.

A case of iatrogenic omental arteriovenous fistula attributable to an earlier unsuccessful liver biopsy is presented. The complications of liver biopsy and the role of arteriography in the diagnosis and management of visceral arteriovenous fistulas are discussed.

Adult↗