Fasting serum cholesterol and triglyceride values in a ten-year prospective study of the 1914-population in Glostrup, 1964-1974.
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Biomedical subjects
Publications and source records attributed to P F Hansen.
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Oral health and dental treatment needs were investigated in 50 randomly selected long-term medicine patients admitted to The Glostrup Hospital, University of Copenhagen, Glostrup, Denmark. All the patients were clinically and radiologically examined. Oral health generally was poor. Two-thirds (66%) of the patients were totally edentulous, 24% partially edentulous. Only 10% were dentate with no dentures. The number of remaining teeth per patient averaged 4.7, that of caries destructed teeth 1.4. All 17 patients with remaining teeth had periodontal disease, and 13 of them suffered from caries. Alveolar ridge atrophy, periapical inflammation, root remnants, impacted teeth and oral mucosal lesions were demonstrated in, respectively, 80, 22, 24, 8, and 26% of the group. In total 82% of the patients needed some kind of treatment, mainly prosthetic and oral surgery. The estimated total treatment time per patient averaged 165 min.
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A daily intake of 3 g magnesium (as magnesium oxide) for six weeks had no effect on serum cholesterol and serum triglyceride in 17 patients suffering from hypercholesterolaemia and/or hypertriglyceridaemia.
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In a trial of lipid lowering drugs a 6 week course of treatment gives reasonably reproducible post-treatment values. Comparison of serum cholesterol and triglyceride levels after treatment should be preferred to percentage reductions, in both individual patients and groups of patients. Therapy with clofibrate combined with Bufor gives lower post-treatment values than does either drug alone. Cholestyramine drugs like Cuemid and Questran give post-treatment cholesterol values which cannot be predicted from the result of clofibrate treatment alone.
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