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Biomedical subjects

P Engelmann

Publications and source records attributed to P Engelmann.

At least 37 records · Page 2Linked to original sources

[Study of the relation of gynecologic and obstetric findings and psychological disorders of pregnancy and the puerperium].

The relationship between gynaecological and obstetrical parameters and psychological troubles in pregnancy and after delivery are a matter of much debate. This arises partly because of different methods of studying the conditions and because of epidemiological studies that have been carried out on this subject. This longitudinal prospective study has been carried out on 211 women who were delivered in the maternity department of Louis Mourier Hospital. The figure for anxiety (in the de Bonis scale of greater than or equal to 20) was 13 to 15% at different times in the pregnancy, of depression (in the CESd scale greater than or equal to 16) was between 11 and 14.5%. 34.5% of those women who had delivered suffered from "baby blues", while 20% had symptoms of depression (CESd greater than or equal to 16 in the first week post-partum) and 6% had a quite obvious syndrome of depression (MADRS greater than or equal to 20). Finally, 18 to 24.5% of women had a major episode of depression (according to the DSM III test) in the year following delivery. As far as risk factors were concerned there was a statistically significant correlation between anxiety and depression in pregnancy and induction of labour, as well as difficulties with the third stage of labour and with an Apgar score of less than 9 in the infant. There was poor correlation between "baby blues" and gynaecological and pathological changes except where vaginal delivery was not spontaneous and where large episiotomies were carried out. On the other hand, women who had pathological labours or cesareans or a general anaesthetic for the third stage had more troubles than others in the year following delivery. Finally, women who showed signs of anxiety or depression in pregnancy or had "baby blues" after delivery were less likely to be able to breast feed their children.

Adult↗

[Endometriosis].

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Choristoma↗

[Icterus and pregnancy].

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Chemical and Drug Induced Liver Injury↗

[Premature detachment of ova diagnosed by echography. Apropos of 42 cases].

The authors noted, while carrying out ultrasound examinations, that there was many cases of abruption of oocytes at the beginning of pregnancy. This study was of 42 cases in 3 maternity units of Paris and its suburbs. It shows up how often, in pregnancies complicated bleeding in the first trimester, ultrasound can demonstrate such abruption. Ultrasound pictures can demonstrate the principal characteristics and the outcome of these abruptions, as well as their effect on the continuation of the pregnancy. In this way it establishes a correlation between the anatomy and the pathology and brings to the fore various hypothesis as to the aetiology of these pathological conditions.

Decidua↗

[Placental localisation : screening and prognosis (author's transl)].

Ultrasounds are the best means at present available for observing the placenta. It follows that it is necessary to appreciate the different phases that occur in placental development. Ultrasound will allow us to work out this evolution and to look for abnormalities that may develop. The placenta becomes an entity at about the 12th week of amenorrhoea. Precise localisation of the placenta is possible in the second trimester of pregnancy, but the final site of the placenta is not fixed in the uterus because different segments develop unevenly. All the same, it is necessary to make a prognosis of the risks of an abnormal insertion of the placenta at the end of pregnancy. It is therefore necessary to be precise in localising the placenta. There are several sources of error which have to be avoided: -- difficulty of exact localisation of the internal os of the cervix. -- the existence of thickening of the myometrium, which forms a reserve for uterine stretch.. These thickenings sometimes come at the same places as the placenta and it may be difficult to differentiate one from the other. -- the presence of placental folds. There are several different elements involving prognosis : -- the site of the lower edge of the placenta in relationship to the internal os. -- the site of the upper edge of the placenta in relationship to the fundus of the uterus. This, statistically, is the best index of prognosis, and so we suggest a classification. -- finally the volume of the myometrium between the lower edge of the placenta and the internal os gives an idea and allows us to work out how the lower segment can stretch. Finally, it is by combining all these elements in a study that a better prognosis can be worked out for the final site of the placenta in the uterus. It is only in the third trimester of pregnancy after the lower segment has formed that the final site of the placenta can be confirmed and that a decision can be taken on the way patient should be treated.

Cervix Uteri↗

[Pregnancy in women wearing a heart valve prosthesis: 5 case histories (author's transl)].

The study of a personal series of five pregnancies and the review of 130 cases published enabled us to recall the physiological, clinical and therapeutic sides of the "pregnancy-heart valve prothesis" combination. Maternal mortality remains at 3%; morbidity, essentially in the form of haemorragic or thrombo-embolic accidents, comes to 45%. We insist on the importance of a pregnancy planned and accepted both by the cardiologist and the obstetrician as contraception is a difficult problem with these patients, classical oestroprogestative methods and intra-uterine devices being too much of a risk. An intake of a progestagen in small doses combines efficiency with innocuity.

Adult↗

The variation of the mean spinability of human cervical mucus throughout the various stages of reproductive life. Automatic measurement and statistical study.

The evolution of the mean spinability value of human cervical mucus was studied by means of an automatic device throughout the menstrual cycle and pregnancy and during and after the onset of menopause. The automatic measurement brings to light the major drawbacks presented by manual methods: values previously obtained should be considered as underestimated. The mean spinability value recorded from cyclic mucus exhibits a very significant increase at mid-cycle. Graphical analysis demonstrates that only small differences in the mean spinability value occur as pregnancy proceeds. A progressive and regular decrease in the mean spinability value can be recorded from the very beginning of the menopause. However, the spinability values observed in premenopausal mucus are noticeably higher than those recorded after the onset of the menopause. The numeric data furnished by the automatic measurement are discussed in terms of statistics.

Cervix Mucus↗

[Pregnancy type nephropathies experimentally induced in rats].

The theory behind our work is the following: toxaemia may be due to the accidental passage of fetal proteins into the maternal organism. Particularly suspect are alpha-fetoproteins from the fetal blood or the amniotic fluid. The experiments were carried out on rats by injecting amniotic fluid or fetal serum into the rats by different routes and rhythms and in different doses. Arterial blood pressure readings showed that the levels were consistently higher than those of controls. The study of the kidneys anatomo-pathologically shows the following triad: intense congestion, tubular lesions, connective tissues affected. These lesions are reversible. The discussion concentrates on the similarities and differences between these findings and pathological changes found in kidneys in pregnancy.

Amniotic Fluid↗