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Biomedical subjects

P Defoort

Publications and source records attributed to P Defoort.

42 records · Page 3Linked to original sources
PubMedDate not supplied

Fetal Doppler flow measurements in the early second trimester: a correlation with fetal outcome.

In 31 women with a singleton pregnancy, abdominal duplex doppler examinations were performed at W16-W17, W26 (+/- 2 weeks) and W34 (+/- 2 weeks) in order to study the flow velocity wave (FVW) indices in the early second trimester and their predictive value for fetal outcome. 24 women with a normal pregnancy outcome were considered as the reference group. In the early second trimester, end-diastolic block occurs frequently at the 150 Hz thump filter setting (15/24 in the fetal descending aorta, 19/24 in the umbilical artery). At the 50 Hz filter setting, end diastolic block appeared in 1/24 cases in the aorta and in 2/24 cases in the umbilical artery. The finding did not persist throughout pregnancy. The flow-velocity indices in the early second trimester in the small-for-dates were comparable to the normal group. We conclude that high peripheral resistance is a common finding in the fetal circulation in early pregnancy. It is not predictive of subsequent growth retardation.

Aorta↗
PubMedDate not supplied

Preterm labor: the role of amnionitis.

This prospective study represents an attempt to find a link between subclinical intra-amniotic infection and preterm singleton labor in 27 asymptomatic patients with intact membranes. Liquor amnii was obtained by transabdominal amniocentesis and cultured for anaerobic and aerobic bacteria and mycoplasmas. None of these cultures was positive. The value of gas-liquid chromatographic determination of volatile and non-volatile acids in liquor amnii could not be determined because amniotic infections did not occur in the population under study.

Amniocentesis↗
PubMedDate not supplied

Capping placenta. A new etiologic factor in midtrimester bleeding.

The results of an echographic study to determine the causal factors in 63 consecutive cases of second-trimester bleeding are presented. True second-trimester bleeding is uncommon (0.8% of pregnancies during the study period), but the impact on fetal outcome is serious because the condition is associated with late abortion, preterm intra-uterine demise, preterm birth, and neurologic sequelae. Various placental structural anomalies occurred in 8% of our cases, and another 8% showed marginal solution of the placenta. In 6% there was retro-amniotic bleeding, whereas placenta praevia was seen in only 3%. The prevailing placental localization (27%) found in patients with second-trimester hemorrhage was a peculiar one in that the placenta literally "capped" the lateral as well as the anterior and posterior walls of the uterine cavity, while the lower margin failed to reach the isthmic region. This type of placentation, which we call capping placenta, occurs in only 2.6% of normal pregnancies. The implication of the findings are discussed.

Congenital Abnormalities↗