Search PubMed⌕ Search

Biomedical subjects

P Day

Publications and source records attributed to P Day.

At least 73 records · Page 4Linked to original sources
PubMed1989

The politics of modernization: Britain's National Health Service in the 1980s.

The history of the British National Health Service (NHS) over the past decade demonstrates both institutional adaptation and insulation from more basic structural change. Reflecting international trends, the NHS has, on the one hand, recentralized decision making, adopted strong managerialist policies, accommodated a modicum of privatization, and stressed the client's role in some service choices. On the other hand, the government has skirted introducing unbridled competition into the health service. Assessment of a 1989 "Government Review" highlights the tensions the NHS faces between budgetary pressures and consumer demands, and between centralized controls and medical autonomy, among others.

Delivery of Health Care↗
PubMed1988

Early indicators of male reproductive toxicity.

Longitudinal data were analyzed for seminal characteristics of rhesus monkeys and beagles. The monkeys were exposed to DBCP; the beagles were exposed to acute or chronic whole body gamma irradiation. The semen was analyzed for volume and sperm concentration. Sperm were measured for percent motility, swimming speed, and head dimensions. Abnormalities of the sperm tail were also noted. All treatments resulted in measurable effects on the semen parameters. Sperm production, as evaluated by seminal sperm concentration or total sperm numbers in the ejaculate, was as informative of testicular toxicity as any other parameter or combination of parameters. A consistent finding was that changes in sperm output occurred concomitantly with changes in sperm motility.

Animals↗
PubMed1987

The regulation of nursing homes: a comparative perspective.

Britain and the United States alike face the question of how best to protect the growing and vulnerable population of nursing home residents through State regulation of private institutions. Despite marked differences in scale, organization, and financing between the two nations, there are striking similarities in the problems encountered and in styles of enforcement adopted in response. Analysis of the regulatory systems in practice shows a convergence in the regulatory process despite the dissimilarities between formal regulatory models. Both systems are responding--however imperfectly--to the social environment of nursing home care. Future regulatory policy will have to encompass formal and informal, legal and social control.

Aged↗
PubMed1987

Stability of cefazolin sodium in various artificial tear solutions and aqueous vehicles.

The stability of cefazolin sodium reconstituted in four artificial tear solutions, two acetate buffer solutions, phosphate buffer solution, and 0.9% sodium chloride injection was studied. Cefazolin was reconstituted in Tearisol, Isopto Tears, Liquifilm Forte, and Liquifilm Tears; acetate buffer solution at pH 4.5 and pH 5.7; phosphate buffer solution at pH 7.5; and 0.9% sodium chloride injection. The solutions were stored at 4 degrees C, 25 degrees C, and 35 degrees C for seven days. All of the solutions were inspected for particulates, turbidity, color, and odor. Five assay determinations on each of three samples of each formulation were performed using a stability-indicating high-performance liquid chromatographic assay. Cefazolin stability was influenced primarily by pH and storage temperature. Reconstitution of cefazolin sodium in the alkaline tear solutions Isopto Tears and Tearisol and in phosphate buffer solution resulted in particulate and color formation at 25 degrees C and 35 degrees C. Turbidity was noted after cefazolin sodium was reconstituted in Isopto Tears. No color or precipitate formation was evident after seven days at 25 degrees C and 35 degrees C in the formulations of acidic pH containing Liquifilm Tears, Liquifilm Forte, 0.9% sodium chloride injection or acetate buffer solution as the vehicles. The extent of degradation of cefazolin was substantially higher in the formulations of alkaline pH than in those of acidic pH at 35 degrees C and 25 degrees C. All of the formulations retained more than 90% of their initial concentration when stored at 4 degrees C. Cefazolin sodium, when reconstituted in artificial tear solutions with an acidic pH, is stable for up to three days at room temperature.

Cefazolin↗