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Biomedical subjects

P Dasgupta

Publications and source records attributed to P Dasgupta.

95 records · Page 6Linked to original sources
PubMedDate not supplied

Age trends of sibling resemblance for height, weight and BMI during growth in a mixed longitudinal sample from Sarsuna-Barisha, India.

BACKGROUND: Even though some studies have considered that sibling resemblance remains constant throughout the life cycle, several investigations emphasize the importance of age and its interactions with genetic and environmental factors in determining sibling similarity in several bodily traits. In fact, the study of age changes in familial resemblance is of great importance for the analysis of certain sources of variation observed in growth processes. AIM: The study examined sibling resemblance for height, weight and body mass index (BMI) in a mixed longitudinal sample from West Bengal, ages 2-19 years, in order to analyse the variations with age of the sibling resemblance for these phenotypes during growth. SAMPLE AND METHODS: Two hundred and forty-five brothers and 213 sisters from 138 middle-class nuclear families living in a semi-urban area of South Kolkata, India were analysed. The analysis of sibling resemblance was performed through correlations estimated by the maximum-likelihood method. The patterns of different trends of sibling resemblance with age were examined by fitting a cubic non-linear regression to the observed correlations. RESULTS: The results show clear variations with age in the sibling resemblance for the traits height and weight, though to a lesser extent for BMI. In general, we found the highest correlation values during the period of infancy, a remarkable decrease during puberty, and a trend of increase towards the end of the growth cycle. CONCLUSION: The study confirms the effect of age on the degree of similarity among siblings for height, weight and BMI in the sample. The sharp decline of correlation at adolescence can be interpreted in terms of the individual variation in age of reaching the adolescent growth spurt.

Adolescent↗
PubMedDate not supplied

A cross-sectional growth study of trunk and limb segments of the Bengali boys of Calcutta.

This report deals with cross-sectional growth of sitting height (SH), subischial length (SL, estimated as height minus sitting height), height of the anterior superior iliac spine (HIS), and total arm length (TAL) of Bengali school boys (Calcutta), aged 7.0-16.0 years. Preece-Baines model 1 (PB1) fits to the cross-sectional means of the four traits estimate the average ages at maximum increment at 12.41 years for SL, at 12.43 years for HIS, at 12.97 for TAL, and at 13.74 years for SH. Maximum increment of the upper and lower segment of the body are reached at an earlier age in the present study than in a longitudinal analysis of semi-urban Bengali boys from the suburban area of Calcutta. Socioeconomic differences and secular trend might explain this shift towards earlier maturation.

Adolescent↗
PubMedDate not supplied

Perinatal mortality in eclampsia in relation to drug therapy.

Fifty-nine babies were born to eclamptic mothers among 7500 deliveries giving incidence of occurrence of 0.77 percent. The perinatal mortality in eclamptic babies was 32.7%, whereas the total perinatal mortality rate amongst all the deliveries was 10.5%. The mothers were treated within Group I--diazepam, Group II i chlorpromazine (largactil), phenargan and diazepam and Group III--largactil, phethidine and phenargan. The mortality rate was 23.8%, 18.8% and 66.6% respectively. The highest number of still-born i.e. six out of 8 occurred in Group III. Hundred percent still-born was noted in 28-32 weeks of gestation and birth weight less than 1.5 kg irrespective of drug regimes. Iargactil potentiates the respiratory depressant effect of pethidine and may cause high rate of still-birth and death after birth.

Adult↗