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Biomedical subjects

P Dano

Publications and source records attributed to P Dano.

At least 37 records · Page 2Linked to original sources
PubMed1989

Early clinical experience with subcutaneous GR43175 in acute migraine: an overview.

In six European clinics 111 migraine patients were treated in a series of open dose-ranging studies with subcutaneous injections of 1 to 4 mg GR43175, a novel 5-HT 1-like receptor agonist. Response rates after 20-30 min were dose related and rose from 33% with 1 mg to 96% with 4 mg GR43175. Side effects were minor and transient. These promising results warrant confirmation in placebo-controlled double-blind trials. Migraine, treatment, 5-HT agonist, open studies.

Adolescent↗
PubMed1988

[Cerebral atrophy and chronic alcoholism].

Fifty chronic alcoholic male patients, were investigated to determine characteristics of alcohol intoxication, neurologic and hepatic complications and degree of cerebral atrophy by CT. CT imaging criteria for definition of alcoholic cerebral atrophy are proposed, discussed and compared with those previously reported. Findings showed that alcoholic cerebral atrophy is added to atrophy due to age and is in correlation with the duration of intoxication. It appears after 40 years of age and increases progressively in parallel with polyneuropathy, cerebellar disorders and dementia. It appears to progress independently of the hepatic lesions.

Aged↗
PubMed1985

[Acute polyradiculoneuritis and toxoplasmosis].

A patient developed acute polyradiculoneuritis during the course of a recent infection due to toxoplasma. A cause/effect relation is discussed and appears likely. A review of 3 published cases failed to determine any specific clinical features of the polyradiculoneuritis. Serology for toxoplasmosis should be included in the etiologic investigations of apparently primary Guillain-Barré's syndrome.

Acute Disease↗
PubMed1983

[Recurrent familial hyperparathyroidism. A propos of 7 adenomas in 3 members of the same family. Review of the literature].

Over a period of 23 years, 3 members of a family of 5 presented with 7 parathyroid adenomas (4 in the first case, 2 in the second case, 1 in the third case). Excision of each adenoma, with systematic pre-operative assessment of the remaining parathyroid tissue, led to complete clinical and laboratory cure of each episode. The delay in the appearance of recurrence was between 3 and 9 years. After reviewing the literature, the authors stress the importance, in any case of hyperparathyroidism, of routinely investigating the serum calcium levels in members of the patient's family, especially if the patient is young and if he has had several episodes or multiglandular involvement in one episode. The authors discuss the literature concerning recurrent familial hyperparathyroidism with endocrine polyadenomatosis and the "hypercalcaemia-hypocalciuria" syndrome.

Adenoma↗
PubMed1983

[Familial and recurrent hyperparathyroidism. Apropos of 7 adenomas in 3 members of the same family. Review of the literature].

Over a period of 23 years, 3 members of a family of 5 presented with 7 parathyroid adenomas (4 in the first case, 2 in the second case, 1 in the third case). Excision of each adenoma, with systematic pre-operative assessment of the remaining parathyroid tissue, led to complete clinical and laboratory cure of each episode. The delay in the appearance of recurrence was between 3 and 9 years. After reviewing the literature, the authors stress the importance, in any case of hyperparathyroidism, of routinely investigating the serum calcium levels in members of the patient's family, especially if the patient is young and if he has had several episodes or a multiglandular involvement in the one episode. The authors discuss the literature concerning recurrent familial hyperparathyroidism with endocrine polyadenomatosis and the "hypercalcaemia - hypocalciuria" syndrome.

Adenoma↗
PubMed1982

[Colonic localization of pseudopolypoid type disclosing Recklinghausen's neurofibromatosis].

A case of colonic Recklinghausen neurofibromatosis found in a forty-two-year-old woman is presented. Only the colon was affected. The first symptom was rectal bleeding. Widespread polypoid lesions involving the rectum, sigmoid, left colon and part of the transverse colon were demonstrated upon barium enema and rectosigmoidoscopic examinations. As demonstrated by a review of the medical literature, colonic involvement in Recklinghausen disease is very infrequent and forms restricted to the colon are exceptional. The pathologic findings and the clinical, radiological and endoscopic features in colonic neurofibromatosis are described. It seems that total colectomy should be advocated. Our patient underwent total colectomy ten years ago and has experienced neither recurrence nor other manifestations of Recklinghausen disease.

Adult↗