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Biomedical subjects

P Dallos

Publications and source records attributed to P Dallos.

At least 109 records · Page 6Linked to original sources
PubMed1975

Electrical correlates of mechanical events in the cochlea.

In this paper the main emphasis is laid on presenting an up-to-date description of the relationships between stimulus-related cochlear potentials: cochlear microphonic (CM) and summating potential (SP) and the preceding mechanical events. To this end, CM and SP (both DIF and AVE SP) magnitude functions, obtained with the differential electrode technique, are shown from various turns of the guinea pig's cochlea as recorded at a constant stapes displacement. The similarity between these curves and corresponding basilar membrane displacement functions is considered. The influence upon CM recording of the distributed nature of the generators, as well as the presence of strong nonlinear effects is discussed.

Acoustic Stimulation↗
PubMed1972

Cochlear inner and outer hair cells: functional differences.

The cochlear microphonic response was measured with differential electrodes from the first and third cochlear turns of normal guinea pigs and those treated with the ototoxic drug kanamycin. Histological controls showed that the outer hair cells in treated animals were missing over the basal half of the damaged cochleas, while the inner hair cells were intact. Measurements are consistent with the hypothesis that the potentials produced by inner hair cells are proportional to the velocity of the basilar membrane, whereas potentials generated by outer hair cells (which dominate the response of normal cochleas) are proportional displacement of the basilar membrane.

Animals↗
PubMed1970

Cochlear summating potentials: composition.

The potential difference across the cochlear partition and the overall potential level of a given cochlear cross section were measured as functions of stimulus parameters and spatial location. It was confirmed that the potential difference is negative in the vicinity of greatest excitation, and it was discovered that in the same region the overall potential level is positive.

Animals↗
PubMed1969

Cochlear distortion: effect of direct-current polarization.

Intermodulation components (combination tones) appearing in microphonic potentials were measured from guinea pig cochleas with and without polarizing direct currents passing through the cochlear partition. At moderate intensities of stimulus the polarization had a qualitatively different effect on the distortion components than on their eliciting primaries or on pure tones simulating the distortion products. At high intensities, the primaries and the combination tones were similarly influenced by the polarizing current. It is concluded that cochlear distortion is a two-stage process, mechano-electrical at low levels and mechano-hydraulic at high levels.

Animals↗