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Biomedical subjects

P Dale

Publications and source records attributed to P Dale.

24 records · Page 2Linked to original sources

In vitro vs in vivo corrosion analyses of two alloys.

The in vitro and in vivo corrosion characteristics of two alloys, cast Co-Cr-Mo (ASTM F75) and wrought Ni-Cr-Mo, were evaluated using electro-chemical corrosion analysis. Two in vitro electrolytic solutions were utilized, an isotonic saline solution consisting of 0.9 w/o NaCl in distilled water and an isotonic saline solution with 10 v/o sterile calf serum. The in vivo environment was created by implanting cylindrically shaped specimens of each alloy into the back muscles of New Zealand white rabbits. Cyclic anodic and cathodic polarization curves were generated for the three test conditions and subsequently were compared. Anodic curves conducted using the isotonic saline and isotonic saline plus serum electrolyte solutions were very similar to the anodic curves generated for the implanted alloy specimens for both alloys. The corrosion rates predicted from the in vitro and in vivo cathodic polarization curves were not statistically different for the three test conditions. Overall, the corrosion data generated using the in vitro environmental conditions adequately predicted the in vivo corrosion behavior of the cast Co-Cr-Mo and wrought Ni-Cr-Mo alloys.

Animals↗

A model of intervention in child-abusing families: a wider systems view.

This paper describes the application of some principles, taken from the modern psychotherapies by a therapeutic team, to the assessment and treatment of serious child abuse. Factors and dilemmas identified from the assessment and decision-making process are outlined, with particular reference to the roles of the various statutory and community agencies involved with such families. The paper demonstrates the ways in which the range of community and professional agencies may play a pathological role, unintentionally contributing to and maintaining child-abusing dynamics in families. The significance of dangerous unintended consequences of well-meaning agency interventions and of covert interagency activities are stressed.

Child↗

[Special fractures of the capitulum humeri (author's transl)].

Whenever radiographs in the elbow region do not present a clear picture, the physician should consider the possibility of a lesion of the capitulum humeri, despite the fact that this is rather rare. In such cases, the anteroposterior radiographs of the elbow may not present any abnormal findings. In most cases, crescent-shaped or elliptic bone chips in the bend of the elbow or dorsally in the interarticular space of the elbow joint will lead to the proper diagnosis. Classification into groups according to Hahn-Steinthal, Kocher-Lorenz and Krösl can lead to errors if employed too rigidly. In our opinion, lateral tomography of the elbow should always be performed whenever there is any suspicion of a lesion of the capitulum humeri. This will definitely clarify the origin and nature of the fragment, which may be of importance for the selection of the surgical approach and the type of surgical treatment chosen.

Adult↗

Measuring variability in early child language: don't shoot the messenger.

Feldman et al. criticize the MacArthur Communicative Development Inventories (CDIs) as having too much variability, too little stability, and insufficient ability to predict early language delay. We present data showing that these characteristics of the CDI are authentic reflections of individual differences in early language development rather than measurement deficiencies. We also respond to their critical assertions concerning sociodemographic influences on the CDI scores.

Child Development↗

Benign breast disease in systemic sclerosis (SSc). A case-control study.

We hypothesized that Systemic Sclerosis (SSc) may affect the breast in the form of Benign Breast Disease (BBD). For the purpose of this study BBD was defined as breast symptoms either detected by the patient resulting in physician consultation, or detected by a physician during the course of a routine consultation, or detected by a physician during the course of a routine physical exam. Forty-one of 47 women with SSc were matched to case controls from two disease groups (RA and OA). Case matching was done for age (+/- 5 years), disease duration (+/- 3 years) and gender. A structured telephone interview was administered to all subjects and controls to determine the frequency of BBD and associated risk factors. The SSc group had a higher prevalence of BBD compared to the RA group (12/41 versus 4/41, p less than 0.04). However, a similar proportion of the SSc patients and OA case controls had BBD (7/28 versus 9/28). These differences could not be attributed to any of the evaluated risk factors. The RA group had a higher frequency and longer duration of NSAID use, suggesting that the increased use of NSAIDs in the RA patients may account for the lower prevalence of BBD, although genetic, hormonal or undetermined factors may be operative. Without an age-matched, "healthy" general population control group it is impossible to determine if the observed difference in prevalence of BBD represents a less than normal prevalence in RA or a greater than normal prevalence in SSc and OA.

Adult↗