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Biomedical subjects

P D Zimskind

Publications and source records attributed to P D Zimskind.

At least 19 recordsLinked to original sources
PubMed1977

Effect of caffeine on urethral pressure.

Urethral pressure profiles have been a useful adjunct in the study of continence. Caffeine, a known smooth muscle inhibitor and skeletal muscle stimulator, is shown to decrease the urethral pressure profile in anesthetized dogs. This would lead one to believe that the smooth muscle component of urethral tonus is the determining factor. Discussions follow on the mechanism of caffeine action and the possible effect of caffeinated beverages on stress incontinence.

Aminophylline↗
PubMed1977

Experimental study with the Scurasil ureteral prosthesis.

The latest generation of Scurasil (dimethylpolisoxane) ureteral prosthesis was used in six dogs as a model for internal urinary diversion in patients with metastatic disease. It was found to cause minimal reaction but carried a high complication rate, including stone formation, end-stage pyelonephritis, and hydronephrosis. Although technically easy to use, modifications in design are necessary prior to use in humans.

Animals↗
PubMed1977

Gross and radiologic anatomy of the canine kidney.

Review of medical and veterinary literature reveals no complete gross or radiologic description of the canine kidney. Yet, this organ is often the recipient of urologic investigation. Therefore, a complete gross study of this organ was carried out and the results are presented.

Animals↗
PubMed1977

Effects of crush and devascularizing injuries to the proximal ureter. An experimental study.

Crush and devascularizing injuries were performed on proximal canine ureters. The pathogenesis of the reaction to these injuries was evaluated by using microbiologic, physiologic, radiologic, biophysical, histologic, and anatomic techniques. The results indicated that within 12 weeks after crush injuries lasting up to 60 min, renal function fully returned and radiologic demonstration of the crush area resolved, even through other radiologic and pathologic changes persisted in hte crushed ureters. The pathophsiologic results of devascularizing injuries that did not resolve spontaneously tended to progress more rapidly and case more serious renal impairment than any of the crush injuries. Devascularizing injuries that resolved tended to be benign in their effect.

Animals↗
PubMed1977

The effect of caffeine on uretheral motility.

An in vivo ureteral perfusion technique combined with a recently described methodology was used to study the effects of caffeine on ureteral motility patterns. Effects of the drug on the disused ureteric stump were also noted. The results showed a dose-related inhibition to complete cessation of peristalsis. Proposed mechanisms of caffeine effect on the ureter are discussed.

Animals↗
PubMed1976

Urology.

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Adenocarcinoma↗