Search PubMed⌕ Search

Biomedical subjects

P D Sturkie

Publications and source records attributed to P D Sturkie.

At least 19 recordsLinked to original sources

Thermally induced peripheral blood flow changes in chickens.

Changes in wattle blood flow (Q) and vascular resistance (R) were examined during both local heating of the wattle and/or general body heating of unanesthetized, male White Leghorn chickens. Q increased and R decreased during both local and general heating. Termination of heating reversed the response. Beta stimulation with isoproterenol markedly reduced R and increased Q in normothermic birds, suggesting the presence of beta receptors in the wattle vasculature. Alpha blockade with phenoxybenzamine also resulted in pronounced vasodilatation, suggesting tonic alpha-sympathetic tone in the wattle vasculature under normothermic conditions. Neither cholinergic blockade with atropine sulfate nor beta-adrenergic blockade with propranolol altered the vascular response to general heating when administered near its peak. Release of alpha-sympathetic tone is believed to subserve the response to general heating.

Acetylcholine↗

Blood flow in mesenteric, hepatic portal and renal portal veins of chickens.

Blood flows were determined by electromagnetic probes placed upon the posterior vena cava (PVC), coccygeomesenteric vein (COCMV), mesenteric vein (MV), and hepatic portal vein (PV) of white Leghorn males. Blood flow in ml/min of non-fasted, unanesthetized males were as follows: (see article). Withholding food for 24 hrs decreased flow significantly only in the MV and PVC. Anesthesia decreased flow in PVC, PV and COCMV. After ligation of PVC, blood was shunted from caudal areas and renal portal circulation to COCMV and liver. Ligation of PV caused a diversion of flow to renal portal circulation and an increase in PVC flow and a reversal of direction of flow in COCMV.

Anesthesia, General↗