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Biomedical subjects

P D Kumar

Publications and source records attributed to P D Kumar.

At least 37 records · Page 2Linked to original sources

Unilateral internuclear ophthalmoplegia and recovery with thiamine in Wernicke syndrome.

Internuclear ophthalmoplegia is usually caused by multiple sclerosis, tumors, or vascular lesions of the brain stem. We report a patient with Wernicke syndrome who presented with a right-sided internuclear ophthalmoplegia. He recovered completely with intravenous thiamine (vitamin B1). There were no lesions in the magnetic resonance image (MRI) of the brain, suggesting a derangement at the cellular level as the cause.

Humans↗

How do peer reviewers of journal articles perform? Evaluating the reviewers with a sham paper.

Peer review process is widely used to assess the quality of scientific research and select papers for publication in biomedical journals. The method lacks standardization and objectivity. To standardize the peer review process, evaluation and rating of the performance of individual peer reviewers using a sham paper is suggested. The present study of 7 reviewers revealed ratings ranging from 0.34 (SD 0.33) to 0.45 (SD 0.5), widely differing from the set standard (ideal 0). This indicates less than optimal performance by the peer reviewers. Feedback to the peer reviewers might help in improving the standards.

Evaluation Studies as Topic↗

The role of coconut and coconut oil in coronary heart disease in Kerala, south India.

Coronary heart disease (CHD) is common in India and, recently, an increase in the incidence of CHD was reported from the South Indian state of Kerala. The traditional Indian diet is low in fat content. The high incidence of CHD in Indians is, therefore, in contrast to western studies that have correlated high fat, saturated fat and cholesterol intake to CHD. Consumption of coconut and coconut oil that contain high amounts of saturated fat and are thought to be strongly atherogenic, are believed to be one of the main reasons for the high incidence of CHD in Kerala. To explore this presumed link, we studied 32 CHD patients and 16 age and sex matched healthy controls. Consumption of coconut and coconut oil was found to be similar in both groups. The groups did not differ in the fat, saturated fat and cholesterol consumption. The results imply no specific role for coconut or coconut oil in the causation of CHD in the present set of Indian patients from Kerala. The exact reason for the high and increasing incidence of CHD among Indians is still unknown.

Adolescent↗