Biomedical subjects
P Cross
Publications and source records attributed to P Cross.
A classification of health computer systems and how it could help in deciding investment requirements.
Investment in information technology by the NHS is reaching unprecedented levels. This is true throughout the service, from the highly publicized district information systems and hospital information support systems to the investment of GPs in microcomputers. To place all these system developments in context, Peter Cross considers the changes in the structure of health computing in the 1980s and sets out a methodology for assessing both the need for computer systems and their success.
Transcardiac passage of thrombus--ultrasonographic visualization.
A patient is described in whom a right atrial thrombus was seen, by two-dimensional echocardiography, in the act of embolizing into the pulmonary circulation.
The cost of interstitial curietherapy using iridium pins and needles.
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Total body irradiation and bone marrow transplantation in Adelaide--a short report on 7 years experience.
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Rapid ward assessment of renal function by reflectance photometric determination of plasma creatinine.
The Ames Seralyzer reflectance photometer and disposable reagent strips for the determination of plasma creatinine were evaluated in the laboratory and on a urology ward over a 3-month period. Principles of the instrument used are described, as are details of the evaluation procedures. Reproducibility of results under optimum conditions gave coefficients of variation less than 7%. Under routine conditions of use, medical staff and laboratory analysts achieved high correlation with the routine laboratory method of analysis (r = 0.986, N = 108: r = 0.996, N = 102 respectively). Potential sources of inaccuracy were identified. Seralyzer determination of plasma creatinine can be rapidly, simply and reliably performed by medical staff on a urology ward, thereby facilitating assessment of renal function governed by clinical requirement rather than by laboratory convenience.
You, the Act and data protection.
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Institutional care of the elderly: a comparison of the cities of New York, London and Mannheim.
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Ventricular cardiac arrhythmias during anesthesia: feasibility of preoperative recognition.
We investigated the occurrence of anesthetic ventricular cardiac arrhythmia (CA) in 104 systemically healthy consecutive patients undergoing general anesthesia, to evaluate the possibility of recognizing preoperatively those patients prone to CA. In 19 (18%) patients, control strips taken before anesthesia showed CA. During anesthesia CA developed in 34 (33%), including 16 during induction, ten during endotracheal intubation, and eight during both events. Older patients had a higher incidence of CA than younger ones (P less than 0.01), and patients with preoperative CA showed a greater trend toward anesthetic CA. There were no anesthetic deaths in this group. Early detection and treatment avoided complications and sequelae of CA. A second anesthetist in the operating room, to monitor the cardiac rhythm during induction and intubation, possibly contributed to early detection of CA and is strongly recommended.
A toothbrushing programme in a school for the intellectually handicapped.
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The epidemiology of depression and dementia in the elderly: the use of multiple indicators of these conditions.
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A cross-national comparison of the institutionalized elderly in the cities of New York and London.
Two random samples, each constituting 0.5% of the institutionalized elderly (over 65) in the cities of New York and London have been compared. This preliminary report of a collaborative study demonstrates the similarity of the 2 samples. Institutions in the 2 cities are shown to differ in size, type of ownership and the frequency that skilled nursing is provided. Some implications of these 2 findings are raised now, and will be discussed later when the full data for the study are presented.
When is the extrapolation of animal carcinogenesis to man inappropriate?
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Liquid scintillation alpha particle assay with energy and pulse shape discrimination.
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[An intractable case of petit mal. Effects of clomipramine].
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An iron-free double-focusing pi square-root of 2 beta-ray spectrometer of 35 cm optic radius.
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"True" versus "apparent" stage I epithelial ovarian cancer: value of frozen section analysis.
The aim of this prospective study was to determine the clinical benefits of introducing peroperative frozen section analysis into the surgical management policy of women referred with an adnexal mass suspicious of ovarian cancer. All women surgically managed at the Northern Gynaecological Oncology Centre, Gateshead, UK, between July 1, 2002, and June 30, 2003, where frozen section analysis had been utilized were included for analysis. Correlation was determined between cases surgically staged following the frozen section result and the clinical need for staging based on the pathologic diagnosis from the paraffin section. During the 12-month period, 130 women underwent frozen section analysis. Paraffin section diagnoses included 74 benign tumors, 11 borderline tumors, 34 primary epithelial cancers, 5 nonepithelial cancers, and 6 metastatic tumors. All primary epithelial ovarian cancers were correctly identified as requiring a staging procedure based on the frozen section result. Four of seventy-four cases reported as benign on frozen section analysis were underdiagnosed; two were later diagnosed on paraffin section as borderline tumors and a further two as malignant (one low-grade adenosarcoma and one primary peritoneal cancer). Of the 130 cases, 55 (42.3%) underwent a staging procedure based on the frozen section result. The value of frozen section analysis in determining the need for the performance of a staging procedure had the following statistical test results: sensitivity = 92%, specificity = 88%, positive predictive value = 82%, and negative predictive value = 95%. Excluding the borderline tumors, metastatic tumors, and primary peritoneal tumor where staging did not impact subsequent clinical management, the statistical test results for frozen section analysis in determining the need for a staging procedure were sensitivity = 97%, specificity = 95%, positive predictive value = 90%, and negative predictive value = 99%. The clinical benefits of introducing frozen section analysis in the surgical staging policy of women with an adnexal mass suspicious of ovarian malignancy included avoidance of a surgical staging procedure in 95% of cases identified on paraffin section analysis to be benign. This benefit was without compromising the avoidance of chemotherapy in true stage I epithelial ovarian cancer cases. Additional benefits included the confirmation of malignancy where extraovarian lesions were suggestive but not indicative of malignant disease, and the intraoperative identification of metastatic disease of nonovarian origin.
Observations on the use of music in rehabilitation of stroke patients.
A preliminary investigation was initiated to explore the use of music as a means of improving general mobility, social interaction, and emotional stability in patients who have suffered a stroke. A literature search had revealed very little information on the use of music in the rehabilitation of such patients. The investigators videotaped a series of sessions involving group movement-to-music, group music-making, and individual movement-to-music. An individual case study in music-making was carried out as well. All videotapes were reviewed and we observed that an increase in the range and ease of movement of the patients occurred during weight-shifting activities, when appropriate music with a tempo of 58 to 63 beats per minute was used. Our observations supported the findings of recent research concerning preferred tempi for certain activities and reinforcement of movement by appropriate tempi. Other factors in our study, such as size of group, placement, cueing, and the opportunity to touch, appeared to affect the responses obtained in group situations. As the result of our observations, we have concluded that music enhances the general mobility and social interaction of patients who have sustained a cerebrovascular accident and that it may also improve a patient's emotional stability.