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Biomedical subjects

P Conti

Publications and source records attributed to P Conti.

At least 145 records · Page 8Linked to original sources
PubMed1980

["Granuloma pouch" reduction after treatment with indomethacin and diflunisal and collateral effects of these drugs on gastric mucosa].

In the present work it was determined the ability of non-steroidal anti-inflammatory drugs (Diflunisal and Indomethacin) to inhibit formation of "granuloma pouch" exudate induced in rats. This study shows that the combined administration of Diflunisal and Indomethacin exerts similar anti-inflammatory activity as the single drugs. There does not seem to be additive anti-inflammatory effects of the drugs in combination but, if anything, a weak antagonism. The association of the two compounds produces a reduced harmful effect on the gastric mucus.

Animals↗
PubMed1980

[The influence of levamisole in vitro on lymphocytes from an immunodeficient patient].

Cultures of lymphocytes from a patient with a suppressed immune-system were set up, and a low response was seen after treatment with mitogenic substances such as PHA and ConA. Other lymphocyte cultures from the same patient were treated with Levamisole, and after this it was noted that the percentage of T-cell rosettes with sheep erythrocytes was increased.

Animals↗
PubMed1980

Role of structured visual field and visual reafference in accuracy of pointing movements.

In a visuo-motor pointing task, the accuracy of response was measured in situations which differ in the visual information available and the speed of execution of movement. Results confirm the role of visual cues received from self-produced movement in the control of the trajectory of a limb. Furthermore, it can be shown that a structured visual background is important in the treatment of sensory data concerned with the movement and in target localization. This effect is absent in rapidly executed pointing response.

Cues↗
PubMed1980

4-[125I] iodophenyltrimethylammonium ion, an iodinated acetylcholinesterase inhibitor with potential as a myocardial imaging agent.

4-[125I]Iodophenyltrimethylammonium acetate (4-I-125 PTMA) was prepared by chloramine-T iodination of N,N-dimethylaniline and subsequent methylation with methyliodide. Purification by thin layer chromatography afforded a product whose specific activity approached the theoretical carrier-free level. Biodistribution studies in normal ICR mice showed a significant accumulation of 4-I-125 PTMA in the heart tissue, with heart-to-blood ratios of 12.5, 10.4, 7.8, 3.4, 3.4, and 3.3 at 1, 5, 10, 30, 60, and 120 min, respectively. Initial uptake in the heart was greater than 26% of the injected dose per gram. Twenty-five percent of the activity was excreted unchanged by the kidneys during the first 5 min. Less than half of the injected activity was retained in mice at 120 min.

Animals↗