Conservative management of intrapancreatic collections after whole pancreas transplantation: report of two cases.
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Biomedical subjects
Publications and source records attributed to P Conort.
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The authors report a case of haematuria secondary to ureteric varices due to a complex venous malformation. After excluding a neoplastic and infectious cause, this rare cause of haematuria must be considered in patients presenting with unilateral upper tract haematuria. In this case, the diagnosis was made during adulthood. It was suspected on intravenous urography and confirmed by computed tomography.
Posterior vertical lumbar incision, described for the first time in 1869 by Simon, provides a simple access to the kidney and offers excellent exposure of the ureteropelvic junction. The technical modifications proposed by Gil Vernet facilitate access to the kidney and reduce the morbidity. The operative technique is described in detail and the authors report their retrospective experience of 71 cases of correction of ureteropelvic junction anomalies (stage 2, 3 and 4). The morbidity was low (19%). Patients returned to work by the 3rd week. 88% of good results were observed at 3 months (84% in initial stage and 4 lesions). This approach should be preferred to the lateral incision or the percutaneous approach due to the simplicity of the technique and the low complication rate.
A patient with undiagnosed cirrhosis presented with massive haematuria 16 years after augmentation colonoplasty. Portal hypertension (PHT) was responsible for a portocaval collateral circulation with vesical varices detected by low pressure endoscopy performed between episodes of haematuria. A very similar case was published in 1991. Surgical haemostatis with partial or total resection of the colonoplasty was only temporarily effective in our patient, who subsequently underwent liver transplantation due to repeated episodes of hepatic encephalopathy. No recurrence of haematuria was observed six years after the diversion. This rare cause of haematuria must be considered in view of the widespread use of intestinal conduits in urology: a dozen cases have been reported after transileal cutaneous ureterostomy, occurring an average of 3 years after the operation. Direct treatment of the varices, either by surgical devascularisation or resection or be endoscopic laser sclerosis or coagulation, is only temporarily effective. Treatment of the PHT appears to be the most effective measure in the long term: beta-blockers administered in the absence of episodes of haematuria or portal by-pass surgery in the case of failure.
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The authors report five cases of fibrous polyps of the urinary tract, which is a rare disease, as Mazeman only reported 12 cases in his review in 1972. These cases confirm the polymorphic nature of the clinical presentation and the site of these tumours of mesodermal origin, essentially composed of richly vascular connective tissue covered with surface epithelium. Treatment is surgical and conservative. The authors performed two junctional resections, one ureterotomy, one ureteroscopic resection and one nephro-ureterectomy for a partially destroyed kidney.
Electromagnetic shock waves are sufficiently powerful to break ureteral stones in situ under X-ray control. Fifty consecutive patients were treated for ureteral stones (20 lombar, 4 iliac, 26 pelvic); the average length was 7.5 mm; 48 times in one session, twice in two sessions. At 6 months, 98% of these patients were stone-free (with IVP control) and one patient was lost to follow-up.
One stage urethroplasties using a cutaneous island pedicle flap have been described by Quartey, Orandi, Marberger, Gattegno and Blandy. Anatomical study after colored injection and dissection shows, for each of them, a good blood supply from large anastomoses between the internal and external pudendal arteries. The pedicle is very well individualized on Quartey's flap.
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ESWL using the HM3 Dornier lithotriptor is a new therapeutic method for cystine stone disease, particularly in patients who have undergone several surgical procedures with or without adjuvant dissolving drugs. We report 3 cases, demonstrating satisfactory fragmentation results. However the rate of stone-free patients was much lower. This situation might be improved by the adjuvant use of dissolving drugs. The preliminary results (Feb 1988) of the European multicenter study (61 cases in 10 centers), confirm our own experience with a 90% fragmentation rate and only 30% stone-free rate for kidney stones and 77% for ureteral stones.
After describing the autonomic nervous system of the lower urinary tract and its neurotransmitters, the authors discuss the recent discovery of new endomorphine group mediators--the enkephalins. There exist enkephalin immunoreactive nerve fibers in the smooth muscles of the bladder and the prostate. This neuromediator is synthetized in the spinal cord in the body of the preganglionic neuron and is carried by the axon flow towards the intramural parasympathetic ganglions of the bladder. The physiological effects of enkephalins are similar to those of morphinics and are antagonized by naloxone. Enkephalins inhibit spontaneous or provoked contractions of the bladder by inhibiting action on the parasympathetic neurons. This property of relaxing the muscles of the bladder, in both volume and pressure, may open up new vistas for uropharmacological research.