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Biomedical subjects

P Conforti

Publications and source records attributed to P Conforti.

At least 37 records · Page 2Linked to original sources

Italian multicenter study on reversible cerebral ischemic attacks: VI--Prognostic factors and follow-up results.

A total of 462 patients (mean age 52 years) affected by reversible focal ischemic attacks (RIAs) were followed prospectively in 8 neurologic institutions in Italy for 4 years. All cases were evaluated with a cerebral angiography and 21% of angiograms were normal. At the end of the follow-up period the cumulated probability for death, stroke, cardiac event and new RIA was respectively 7%, 8%, 3% and 36%. The predictive value of the baseline characteristics of this series was evaluated by a multifactorial analysis which showed that RIA and stroke (specific cerebrovascular risk) were more likely to develop in patients with a history of more than one RIA and in those in whom multiple vascular territories were involved. Moreover, previous myocardial infarction, intermittent claudication, angina pectoris, time elapsed since the first attack, and duration and severity of the attack itself were independently associated with general cardiovascular risk (death, stroke and myocardial infarction). We conclude that predictive factors, and thus also pathogenetic mechanisms, may be different for general cardiovascular risk and specific cerebrovascular risk in RIA patients.

Adult↗

Kinking and coiling of the internal carotid artery: Clinical-statistical observations and surgical perspectives.

The incidence of kinking and coiling of the internal carotid artery in an unselected series of 1,010 angiographies is reported. The angiographies of patients with cerebrovascular insufficiency and those of patients with other brain diseases were separately reviewed. On the basis of a statistical comparison, the finding of kinks and coils appears significantly higher in "vascular" than in "non-vascular" patients. The greater difference concerns age subgroups up to 50 years. These data give support to the assumption that both kinking and coiling of the internal carotid artery may play a role in determining cerebral ischemic attacks. Surgical experience concerns a series of 19 patients operated by various corrective procedures, including resection of the internal carotid artery and end-to-end anastomosis. It is felt that surgery, performed in appropriately selected cases, can afford significant benefits to cerebrovascular patients, especially those presenting recurrent ischemic episodes.

Adult↗

Late onset of a large cavernous aneurysm after spontaneous disappearance of cerebral arteriovenous malformation. Case report.

A large intracavernous aneurysm (Icav. An) revealed eighteen years after the spontaneous disappearance of a cerebral arteriovenous malformation (AVM) is reported. The main hypotheses to explain the pathogenesis of the association of such malformations and the potential for spontaneous regression of AVMs are reviewed on the light of relevant literature. The multiple congenital vascular anomalies hypothesis is stressed to explain the late onset of Icav. An in this patient.

Female↗