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Biomedical subjects

P Chavaz

Publications and source records attributed to P Chavaz.

49 records · Page 3Linked to original sources
PubMed1981

[Three cases of lichen nitidus in black people (author's transl)].

Report of 3 cases of lichen nitidus in black people. The last publications and our observations allow us to confirm that this affection occurs as frequently in white as in black people but is recognised more easily in black people in whom it takes a characteristic depigmented aspect. The relationship between lichen nitidus and lichen planus is briefly discussed.

Black People↗
PubMed1980

Hypergammaglobulinemic purpura and Sjögren's syndrome in a child.

Hypergammaglobulinemic purpura of Waldenström and Sjögren's syndrome are rarely reported in children. This paper reports the case of a 12-year-old girl suffering from both diseases. In the serum of this patient the presence of circulating immune complexs was demonstrated, but there was no clinical sign suggesting an immune complexe disease. After a 28-month follow-up no clinical or biological change was observed.

Antigen-Antibody Complex↗
PubMed1979

[Ultrastructural study of Mibelli's porokeratosis. Pathogenic and therapeutic considerations in three cases].

Report of three cases of porokeratosis Mibelli with emphasis on the ultrastructural changes of the entire epidermis underlying the cornoid lamella: autophagocytosis, filamentous degeneration, formation of "corps ronds". These phenomena are correlated with those of apoptosis (or intraepidermal cellular death with filamentous degeneration). Its role in the genesis of the cornoid lamella and in the degeneration of the lesions is discussed. In conclusion, on the basis of the reported observations and of the studies showing the action of retinoic acid and its derivatives on precancerous lesions, the authors propose to treat the actinic disseminated form of porokeratosis Mibelli with the aromatic derivative of retinoic acid (RO 10 9359).

Epidermis↗
PubMed1976

Morphometric and enzyme histochemical behaviour of the kidney of young rats before and after unilateral nephrectomy.

Four week old male Wistar rats were unilaterally nephrectomized, and one, two, four, fourteen, and twenty-eight days after the operation the remaining kidneys were removed for morphological examination--including measurement of diameters of the tubules--and for histochemical investigation of enzymatic activities in the nephrons. The following enzymes were examined: succinate DH, lactate DH, alpha-glycerophosphate DH, isocitrate DH, glucose-6-phosphate DH, cytochrome oxidase, adenosine triphosphatase, alkaline and acid phosphatases. In comparison with kidneys of control animals of the same age and sex, the hypertrophy of the remaining kidney was found to be, even in these young rats, entirely due to enlargement of preexisting nephrons. The measurements have indicated that the hypertrophy was most distinct between the second and fourth day after uninephrectomy. Four weeks after the operation the diameters of proximal and distal tubules were about 21% and 18% respectively bigger in the uninephrectomized animals than in the corresponding controls. This increase in size was accompanied by some changes in intensity of enzymatic staining reactions; after an initial diminishment, a graduate increase in activity of almost all the observed tubular enzymes was found; this seems to be the expression of the functional compensation by the remaining kidney.

Adaptation, Physiological↗