Biomedical subjects

P Carr

Publications and source records attributed to P Carr.

At least 73 records · Page 4Linked to original sources

PubMed1985

Analytical evaluation of the purity of commercial preparations of Cibacron Blue F3GA and related dyes.

The composition and purity of three commercial preparations of the widely used affinity chromatography ligand Cibacron Blue F3GA have been evaluated by TLC and by paired-ion reversed-phase HPLC and were found to contain several chromophoric species. Stepwise synthesis of the reported dye structure showed that only one commercial preparation contained any actual Cibacron Blue F3GA, and that it was present only in minor amounts. In all three preparations the major component appears to be the dichlorotriazinyl precursor of Cibacron Blue F3GA. Commercial samples of the related dyes Procion Blue MX-3G and Procion Blue MX-R are also highly heterogeneous. In addition, our experiments suggest that TLC results must be evaluated carefully to ensure that catalytic surface activity of alumina and silica has not created ghost bands.

Anthraquinones↗

PubMed1985

A tiny warrior.

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Female↗

PubMed1984

Knowledge of diabetes and glaucoma in a rural North Carolina community.

Effective use of time, money, and personnel in the delivery of health care services to rural areas requires baseline information on the target population with respect to the problem being addressed. Prior to the initiation of an educational program on diabetes and glaucoma, the Public Health Department of Davie County, North Carolina, conducted a survey of county residents to determine knowledge, attitudes, and practices concerning these illnesses. The goals of the survey were to determine (1) basic knowledge with respect to the nature of each illness, symptoms, and high-risk groups, (2) the stigma attached to each illness, and (3) health practices in terms of previous tests for diabetes and glaucoma and whether or not the respondents know where to go for such tests. Information was obtained through a telephone survey of randomly sampled households in Davie County. Results of the survey indicated that the level of knowledge for both diabetes and glaucoma is particularly low with respect to identification of high-risk groups and symptoms, and approximately one-quarter of all respondents felt there was some stigma attached to diabetes and glaucoma. The lowest levels of knowledge were observed in the youngest and oldest respondents, males, the unmarried, and those with low levels of educational attainment. The differences in knowledge by age, marital status, and sex were found to be partially a function of differing levels of educational attainment. These data have provided information useful in the selection of content areas for the programs and in the identification of target populations for special emphasis.

Adolescent↗

PubMed1982

Action of beta-cell tropin on insulin secretion in vivo and on lipid synthesis.

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Adipose Tissue↗

PubMed1981

Self-induced myocardial infarction.

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Adult↗

PubMed1981

Relapsing polychondritis.

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Humans↗

PubMed1977

Hormonal changes associated with testicular atrophy and gynaecomastia in patients with leprosy.

Basal LH, FSH, 17 beta-oestradiol and testosterone and the gonadotrophin responses to luteinizing hormone releasing hormone (LHRH) were studied in male patients with leprosy (twenty-four with lepromatous and six with tuberculoid leprosy). The mean basal LH and FSH was significantly elevated in the lepromatous group and was associated with an excessive response of both gonadotrophins following LHRH administration. The mean basal testosterone and 17 beta-oestradiol values in the lepromatous group were significantly lower than those of the tuberculoid and control groups. The abnormal gonadotrophin and sex steroid values in the lepromatous group are in keeping with the testicular atrophy and gynaecomastia accompanying this form of leprosy. However, the lack of a significant correlation between basal FSH and testicular atrophy should be noted. In addition, no correlation between any of these hormonal values and gynaecomastia could be demonstrated. The patients with tuberculoid leprosy had essentially normal hormonal profiles (except for two who had raised 17 beta-oestradiol values). This is compatible with the lack of gonadal involvement in these patients.

Adolescent↗

PubMed1973

The clinical and endocrinological effect of oestradiol implants at the time of hysterectomy and bilateral salpingo-oophorectomy.

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Castration↗

PubMedDate not supplied

Research, academic rank, and compensation of women and men faculty in academic general internal medicine.

OBJECTIVE: To evaluate the status of men and women faculty in academic general internal medicine, including their professional training, faculty responsibilities, research performance, academic rank, and compensation, to determine whether systematic differences exist by gender. DESIGN/SETTING: The authors analyzed responses to a 55-part questionnaire sent to all full-time general internal medicine faculty at the major teaching hospitals in the United States. Unadjusted means were generated for men versus women faculty in demographics, training background, hours of work, professional time allocations, institutional support, professional self-assessment, research performance, academic rank, and compensation. Means were recalculated after adjusting for other variables using multivariate methods. RESULTS: The authors found no significant difference in the frequency of fellowship training between men and women faculty. Women and men perform similar professional activities, but even after multivariate adjustment, women devote less time to research and perceive less research skill and institutional support for their research, but have similar numbers of grants, abstracts, and publications in refereed journals and have similar academic ranks. Women faculty, however, receive lower compensation than do men faculty, even after adjustment. CONCLUSION: While the characteristics of men and women faculty are quite similar, including those defining their academic productivity, important differences exist in research time, perceived institutional support, and compensation. These differences cannot be explained by such obvious factors as age differentials, academic rank, or hours of work per week.

Adult↗

PubMedDate not supplied