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Biomedical subjects

P Campos

Publications and source records attributed to P Campos.

28 records · Page 2Linked to original sources
PubMed1989

[Pott's disease in children].

Twenty seven cases of Pott's disease in children between 6 months and 14 years of age are reported. They were observed during a two years period, with a follow-up time till 18 months. In report to their ages 67% were lower than 6 years old and two of them lower than one year old. There was a male sex predominance. The 'hump' sign was the most frequently observed. The most frequent damage localization was at dorsal level. All patients received treatment with four drugs, 14 of them needed orthopedic methods, and only 6 were submitted to surgical correction. In more than 50% of the patients there was good outcome toward cure or improvement with sequelae.

Adolescent↗
PubMed1989

A rational proposal for plasmid nomenclature.

We propose a more rational system for nomenclature of wild plasmids of bacteria. With this proposal for nomenclature of bacterial plasmids, it is established in an unambiguous way: 1) if a plasmid is wild or derivative, and 2) in which species and bacterial strain it was found (in the case of wild plasmids).

Plasmids↗
PubMed1989

[In vitro cultivation of tooth germs (in mice)].

Mouse molars tooth buds on the bell stage were cultured, to investigate the best medium for their maintainance and their eventual clinical use. Tooth germs were cultivated during 3 to 8 days in three different medium: Eagle basal medium (liquid medium), agar-solidified medium and chick chorioallantoic membrane. The grafts were examined by light microscopy. Mesenchymal and atypical cells were counted in experimental and control groups. Our results showed that liquid medium was the best for 3-days buds cultures. Chorioallantoic membrane and agar-solidified medium showed better results for the maintainance of bud cultures for 8-day test. The objective of this study is to maintain in vitro tooth buds cultures for future transplants. This will also provide for the possibility of a more in-depth study of normal odontogenesis.

Animals↗
PubMed1988

Osteoglophonic dysplasia: a new case.

A new case of osteoglophonic dysplasia is described in a Portuguese boy. The clinical and radiographic features are similar to the five previously described cases. The boy died suddenly at 10 months of age.

Abnormalities, Multiple↗
PubMed1981

Translocation (X;6) in a female with Duchenne muscular dystrophy: implications for the localisation of the DMD locus.

A female with Duchenne muscular dystrophy who was a carrier of a balanced translocation t(X;6)(p21;q21) is reported. Four other previously described (X;A) translocations associated with DMD share with the present case a breakpoint at Xp21. The extremely low probability of five independent (X;A) translocations having a breakpoint at Xp21 points to a non-rand association of this site with the DMD phenotype. A DMD locus at Xp21 could be damaged by the translocation, giving rise to Duchenne muscular dystrophy. Alternatively, a pre-existing DMD gene could weaken the chromosome, favouring breaks at Xp21.

Child↗
PubMedDate not supplied

Spraying houses in the Peruvian Andes with lambda-cyhalothrin protects residents against cutaneous leishmaniasis.

A household vector control trial was carried out in the Peruvian Andes to measure the effect of spraying inside walls and ceilings with lambda-cyhalothrin on the risk for residents of cutaneous leishmaniasis caused by Leishmania peruviana. The mortality rates of Lutzomyia verrucarum measured with WHO contact bioassay cones set on adobe walls characteristic of the endemic region indicated an LD95 for lambda-cyhalothrin of about 20 mg/m2, and no reduction in effectiveness for at least 6 months on indoor adobe walls sprayed with 25 mg/m2. A random selection of 112 houses were sprayed (starting in 1992/93) at 6-monthly intervals with a mean dose of 34 mg/m2, leaving 154 control houses (with closely matched pre-intervention measurements of incidence and sandfly abundance). Comparisons of pre- and post-intervention sandfly indoor abundance, measured at regular intervals for up to 2 years using CDC light traps, in 22 sprayed and 21 control houses demonstrated that spraying significantly reduced the indoor abundance of Lu. verrucarum by an average of 78% and of Lu. (Helcocyrtomyia) peruensis by 83%. Spraying was also associated with a significant reduction of 77% in the proportion of bloodfed sandflies collected in light traps. The proportion of susceptible householders acquiring leishmaniasis during the trial was significantly reduced by 54% as a result of spraying. The observed impact of spraying was greatest, 81% (95% confidence intervals 20-95%), when the cases detected during the first 6 months after the intervention were excluded from the analysis, suggesting a significant pre-patent period.

Animals↗
PubMedDate not supplied

[Neurological involvement in free living amebiasis].

INTRODUCTION: Free-living amoeba infection is today a known and outgrowth disease, which is suspected when exists a special skin lesion. DEVELOPMENT: Balamuthia mandrillaris is one of these amoebas recently categorized and identified as a cause of meningoecephalitis granulomatous and chronic. Human infection: until 1997 in Cayetano Heredia Hospital (Lima, Peru) was described 24 cases of Balamuthia mandrillaris infection, 10 under 15 years old. All had skin lesion and all died, 16 had conscious impairment, 8 intracranial hypertension and 8 seizures. CONCLUSIONS: The free-living amoebas disease is now an outgrowth illness that depends on its worldwide distribution and association with immunocompromised host. The Balamuthia mandrillaris infection is a new form responsible for a fatal disease and clinical suspected is possible by the occurrence of skin lesion. Is very important to promove in Latin America collaborative studies in order to future actions.

Acanthamoeba↗