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Biomedical subjects

P C Muzzio

Publications and source records attributed to P C Muzzio.

At least 37 records · Page 2Linked to original sources
PubMed1991

[Measurement of gastric emptying with Tc 99m. Technique and reliability of the test].

Among the various methods used to measure gastric emptying time, scintigraphy is nowadays the technique of choice. Since only few data are available on the operative characteristics of the method, the authors investigated reproducibility, sensitivity, and specificity of a modified scintigraphic technique for the measurement of gastric emptying time. Three groups of subjects--healthy volunteers, patients with functional dyspepsia, and patients with upper gastrointestinal conditions--were administered liquid meals having various standard consistencies (349 tests on the whole). In both healthy volunteers and dyspeptic patients the method had high sensitivity (72%), good specificity (69%), and low intra-subject variation (25%). In all cases, the increase in meal density produced a delay in gastric emptying. Dyspeptic patients had slow gastric emptying of high-fiber meals, while in duodenal ulcer and in atrophic gastritis emptying was significantly faster. The radionuclide method proved valuable in measuring gastric emptying and was useful to confirm the pathogenesis of the various conditions. As for functional and organic pathologic conditions, it allowed treatment efficacy to be evaluated.

Adult↗
PubMed1991

Elastofibroma: CT and MR findings.

Two cases of elastofibroma of the chest wall are reported. Each patient was investigated with CT and, in 1 case, MR imaging was also performed. Elastofibroma appears like a mass in the subscapular region and often presents problems of differential diagnosis. The contribution of MR imaging is reported.

Adult↗
PubMed1988

Pancreatic cancer: CT scan.

The results of 72 cases of histologically confirmed pancreatic neoplasm are reviewed. By applying a semeiological scheme, which considers intra and extrapancreatic alterations, it is shown that the possibility of a pre-invasive diagnosis on CT is still limited, and requires further confirmation. CT examination is unique for demonstrating the extension of the lesion, and provides truly probative findings for a specific diagnosis, especially when signs of direct local or distant invasion appear.

False Negative Reactions↗
PubMed1988

Pancreatic carcinoma, diagnostic ERCP.

Fifty-three patients underwent endoscopic retrograde cholangiopancreatography (ERCP). Thirty-eight patients had pancreatic disease, diagnosed on the basis of surgical and/or instrumental-clinical findings, and consisted of 17 cases of carcinoma (group A), 10 cases of chronic pancreatitis with benign stenosis of the pancreatic duct (group B), and 11 cases of chronic pancreatitis without stenosis (group C). Linear discriminant analysis was employed to evaluate differential diagnosis data relative to secondary pancreatic ducts. With this method, 16/17 patients (94%) were correctly assigned to group A (high sensitivity), 7/8 patients (88%) to group B, and 7/10 patients (70%) to group C. A readily found radiological sign, such as abrupt and/or irregular stenosis of the pancreatic duct enables the correct diagnosis of carcinoma, but while this criterion is highly specific, it is poorly sensitive. If a clearly neoplastic stenosis of the main duct is not present, an analysis of the secondary ducts is determinant.

Cholangiopancreatography, Endoscopic Retrograde↗
PubMed1988

[Radiologic diagnosis of anal fistulae with radio-opaque markers].

Fistulography classifies anal fistulas in low-below puborectalis muscle-, high-above puborectalis muscle-, and middle. This classification increases the scope and accuracy of radical surgery. In order to improve the diagnostic reliability of anal fistulography the authors point out the importance of radio-opaque markers for anatomical definition of the anorectal region. Thirty patients (25 males and 5 females; mean age: 47 years) were studied by anal fistulography using radiopaque markers: a Foley's 22 Fr catheter, with distal balloon filled of idrosoluble radiopaque contrast medium, was placed in the anal canal; a metal marker was fixed to the anus. In order to demonstrate the relationship between fistula and puborectalis muscle, we subdivided the anal canal in 3 equal segments: high, middle and low. The idrosoluble contrast medium for fistulography is injected through a pediatric Foley's catheter 8 Fr when external opening is large enough, and through a K7072 endovenous catheter when the opening is small. Fistulous tract was visible in all patients: internal fistulous opening in 23/90 cases, and relationship of fistulous tract to puborectalis muscle in 25/30 (83.3%). In demonstrating either secondary fistulous tracts or abscesses, fistulography with radiopaque markers was correct in 60% of cases; in 20% of patients some of the above-mentioned complications were demonstrated, and in the 20% no complications at all were detected.

Adult↗
PubMed1987

[Behavior of T1 relaxation time in normal and neoplastic pulmonary tissue. An in vitro study].

The aim of the study was to look for a difference between normal and neoplastic lung tissue by means of Magnetic Resonance Spectroscopy in vitro. A 2.1 Tesla intensity spectrometer was used. From 23 pneumonectomized patients, two samples from the lung were taken immediately after surgery: one from the center of the neoplasm, one from the healthy surrounding tissue; on each of them T1 relaxation time was measured. Twenty patients out of 23 had a higher T1 relaxation time in the pathologic tissue than in the healthy surrounding tissue; only in 3 cases the T1 of neoplastic tissue was lower than that of the healthy tissue. A correlation was also sought between the T1 value and the histologic type of the neoplasm. In epidermoid carcinoma, the T1 relaxation time increased with the malignity of the neoplasm.

Adenocarcinoma↗
PubMed1986

[Duodenal and colonic involvement in neoplastic pathology. Anatomical and radiological considerations].

The authors present 3 cases of duodeno-colic involvement by malignant neoplasms and analyse the main radiological features. Benign and malignant duodenocolic fistulas are discussed and colic lesions caused by an extrinsic process. Guiding radioanatomical criteria are stated namely the alterations in the site of the principal lesion first and, afterwards, the morphological changes or displacement of the bowel.

Adenocarcinoma↗
PubMed1986

[Radiologic methods in the evaluation of upper esophagoplasties].

Post-operative radiologic control of esophageal plastic surgical procedures in pathologic conditions of the cervical esophagus involves difficulties due to the poor collaboration of the patient, who swallows only small quantities of contrast medium. Contrast medium injection through esophageal-gastric probes, and its reflux toward the cervical region with the Trendelemburg position and/or straining, enables the demonstration of fistulas otherwise unrecognized.

Administration, Oral↗
PubMed1985

[Radiological and instrumental study of the colon in idiopathic constipation].

It has been demonstrated that it is not always possible to attribute to constipation a reduced colonic transit time as being evidenced by radiological studies using radiopaque markers. In fact, in constipated patients with a normal transit time, it was more reasonable to consider a recto-anal disorder as evidenced by defecography and manometry.

Anus Diseases↗
PubMed1984

[Radiological examination of esophagoplasty interventions for esophageal cancer].

The experience in the radiological study on the esophagoplasty for esophageal cancer is reported. In the various types of surgical operations: gastroplasty: 284 cases, colonplasty: 28 cases, jejunoplasty: 10 cases, substitution of the cervical esophagus: 74 cases, the radiological contribution is analysed both in the early anastomosis check: after 7 days the intrathoracic and after 10 days the cervical ones, and in the distance check. For this last aspect, particularly the functional pattern, it is also suggested the use of paraphysiologic meals.

Esophageal Neoplasms↗
PubMed1980

Computed tomography of the liver in von Gierke's disease.

The computed tomography findings in the liver of a patient with von Gierke's disease are presented. Precontrast scans demonstrated diffuse decreased density throughout the liver. In the postcontrast scans, a focal right sided hyperdense area was visualized.

Adenoma↗