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Biomedical subjects

P C Amadio

Publications and source records attributed to P C Amadio.

At least 19 recordsLinked to original sources

Italian version of the Disability of the Arm, Shoulder and Hand (DASH) questionnaire. Cross-cultural adaptation and validation.

An Italian version of the Disability of the Arm, Shoulder and Hand (DASH) questionnaire has been devised and its reliability and validity have been assessed in a cross-sectional study of 108 consecutive patients with upper extremity pathologies. A sub-sample of 30 patients was used to assess re-test reliability. The principal DASH scale showed a high correlation with other patient-oriented measures and demonstrated good reproducibility, consistency and validity, which were similar to those for other languages' versions of DASH. These findings suggest that the evaluation capacities of the Italian DASH are equivalent to those of other language versions of the DASH.

Arm↗

Pulley plasty versus resection of one slip of the flexor digitorum superficialis after repair of both flexor tendons in zone II: a biomechanical study.

BACKGROUND: The outcome of repair of zone-II lacerations of the flexor digitorum superficialis and flexor digitorum profundus tendons remains suboptimal. We investigated the effects of two strategies to improve postoperative gliding in a human cadaveric hand. METHODS: The second, third, and fourth digits were harvested from ten fresh-frozen human cadaveric hands. Complete lacerations and repairs were made to the profundus and superficialis tendons at a location where both repair sites would pass beneath the A2 pulley with the proximal interphalangeal joint in 45 degrees of flexion. The gliding resistance of the flexor digitorum profundus tendon was measured following pulley plasty and following excision of one slip of the flexor digitorum superficialis. The breaking strength of the remaining slip of the flexor digitorum superficialis tendon was then measured. RESULTS: Pulley plasty and resection of one slip of the flexor digitorum superficialis tendon both significantly decreased gliding resistance compared with repair of both slips (p < 0.001). There was no difference in the mean gliding resistance between the pulley plasty and one-slip resection groups. The flexor digitorum superficialis slip was stronger after repair with a Becker suture (28.8 +/- 9.0 N) than after repair with a modified Kessler (16.4 +/- 4.5 N) or a zigzag suture (15.0 +/- 5.7 N). CONCLUSION: Both pulley plasty and resection of one slip of the flexor digitorum superficialis reduce gliding resistance after tendon repair in zone II of the hand.

Adult↗

Gliding resistance after repair of partially lacerated human flexor digitorum profundus tendon in vitro.

OBJECTIVE: This study reports the gliding resistance between repaired, partially lacerated tendon and pulley in human cadaver digits, using several commonly employed repair techniques. BACKGROUND: Suture techniques with multi-strands and locking loops have been recommended to reduce the risk of rupture of the repair tendon with early active motion. Such sutures may increase the gliding resistance, and the gliding resistance after tendon repair is also an important factor influencing the rehabilitation. METHOD: 105 specimens of second, third, or fourth fingers from 36 adult human hands were tested for the gliding resistance between flexor digitorum profundus tendon and A2 pulley in the normal condition. After an 80% laceration, each tendon was repaired with one of the following suture techniques: (1) Kessler; (2) modified Kessler; (3) Savage; (4) Lee; (5) Tsuge; and (6) Becker. All suture techniques were reinforced with a circumferential epitenon simple running suture. After tendon repair, the gliding resistance was remeasured. RESULTS: The gliding resistance of the Becker repair was significantly greater than each of the other four repairs (P<0.05). The resistance of the modified Kessler repair was significantly less than that of the Kessler, Savage, or Tsuge repairs. CONCLUSIONS: We conclude that the type of tendon repair can significantly affect the gliding resistance between the tendon and pulley system after tendon repair. RELEVANCE: The design of the tendon repair, through its effect on friction, may have an adverse effect on the clinical results of tendon mobilization.

Aged↗

Gliding characteristics of tendon repair in canine flexor digitorum profundus tendons.

The gliding resistance between the flexor digitorum profundus (FDP) tendon and the proximal pulley system was measured using the method of S. Uchiyama, J.H. Coert, L. Berglund, P.C. Amadio, K.N. An (J. Orthop. Res. 13 (1995) 83) in 108 adult dog digits in vitro. The FDP tendons were then lacerated to 80% of their transverse section. Each tendon was repaired with one of the following six suture techniques: Kessler, modified Kessler, Savage, Lee, Becker and simple running suture alone. Each repaired tendon was then tested again using the same method. The Student-Newman-Keuls test for multiple comparisons was performed for statistical analysis. The average gliding resistances of the Kessler, Savage, and Becker repairs were significantly greater than the resistances of the Lee, modified Kessler, and running suture alone repairs (P < 0.05). The Lee suture technique had a significantly greater resistance than the modified Kessler repair and the running suture (P < 0.05). The results of the peak gliding resistance followed the same trends, except that the modified Kessler repair was significantly higher than the running suture alone (P < 0.05). Suture techniques with a multi-strand core suture, with knots located outside the tendon surface, and with multiple-loops on the tendon surface may result in increased gliding resistance between the tendon and pulley system after tendon repair.

Animals↗

Tensile properties of suture methods for repair of partially lacerated human flexor tendon in vitro.

The decision to treat zone II partially lacerated flexor tendons is challenging, because there can be justification for either repair or no repair, depending on the surgeon's assessment of the strength of the residual intact portion of the tendon. In this study tensile properties of various repair techniques were compared. Cadaveric human flexor tendons (n = 118) were lacerated to 75% of their cross-section and repaired with either a core suture method (Kessler, modified Kessler, Savage, Lee, augmented Becker, or Tsuge all finished with a circumferential running suture), an epitendinous suture alone (circumferential or partial), or the tendons were left unrepaired. Among the core suture methods there was no significant difference (p >.05) in maximum failure force (overall mean, 211.2 N; SD, 53.2) or force to produce a 1.5-mm gap (74.1 N; SD, 49.7). Likewise there was no significant difference (p >.05) in tendon stiffness (41.0 N/mm; SD, 14.0) or resistance to gap formation (52.3 N/mm; SD, 23.1). In comparison, repairs without the core suture, including unrepaired tendons, were significantly weaker (144.7 N, p <.001) and had a marginally lower stiffness (p =.04) but had a similar resistance to gap formation (43.5 N/mm).

Hand Injuries↗

Suture techniques with high breaking strength and low gliding resistance: experiments in the dog flexor digitorum profundus tendon.

We studied the breaking strength and gliding resistance between the pulley and flexor tendon for various suture techniques. Canine flexor digitorum profundus tendons were transected and sutured using one of eight repair techniques: modified Kessler (MK); Tsuge (Tsuge); two variations of a double modified Kessler (DK1, DK2); combined modified Kessler-modified Tsuge (MKT); augmented Becker (Becker); Cruciate (Cruciate); and modified double Tsuge (DT). The force to produce a 1.5 mm gap, ultimate failure load, resistance to gap formation, and gliding resistance were measured. The force to produce a 1.5 mm gap and the ultimate breaking force were higher with the DK1, DK2, MKT, Becker, Cruciate, and DT repairs than they were with the MK and Tsuge repair, while the gliding resistance of the Becker was higher than that of the MK, DK1, DK2, MKT. Cruciate, and UT repairs. In addition to confirming that repair strength increases as the number of strands crossing the repair increases, we also found that these stronger repairs need not produce higher gliding resistance than less robust repairs.

Animals↗

The effect of suture technique on adhesion formation after flexor tendon repair for partial lacerations in a canine model.

BACKGROUND: Adhesion formation is a serious problem after flexor tendon repair. Many repair techniques have been developed to increase the suture strength after tendon repair surgery. The purpose of this study was to assess adhesion formation with different suture techniques in an in vivo canine model. METHODS: Sixty flexor digitorum profundus tendons were partially lacerated (80%) and repaired with either a modified Kessler (MK) or Becker (MGH) suture technique and supplemented with a simple running suture. The dogs were sacrificed at 1 week, 3 weeks, or 6 weeks after surgery and the repaired tendons were evaluated for adhesion breaking strength. RESULTS: At 1 week there was no significant difference between the two repair groups (p > 0.05). At 3 and 6 weeks, the adhesion breaking strength in the MK suture group was significantly less than that of the MGH suture group (p < 0.05). CONCLUSION: High friction suture techniques may cause more adhesion formation than the lower friction suture techniques under passive postoperative therapy.

Analysis of Variance↗

The effect of knot location, suture material, and suture size on the gliding resistance of flexor tendons.

The effect of knot location, suture material, and suture size on gliding resistance between the pulley and flexor tendon was investigated in a canine model. Different suture materials [monofilament nylon (Ethilon), braided polyester suture coated with silicone (Ticron) and uncoated braided polyester suture (Mersilene)] and suture sizes (4-0, 5-0) were tested. A knot was made on either the volar surface, on one lateral side, or on both lateral sides of canine hind-paw tendons, and gliding resistance was measured. In addition, the frictional coefficient between three suture materials (4-0 nylon, 4-0 Ticron, 4-0 Mersilene) and a nylon rod were measured. The gliding resistance of the tendon with knots on both sides was highest, while tendons with one lateral knot had the lowest resistance (p < 0.01). The gliding resistance of 4-0 suture size was higher than that of 5-0 size (p < 0.0001). The coefficient of friction of nylon was lower than that of braided polyester suture (Ticron or Mersilene) (p < 0.001). The placement of knots and choice of suture material affect gliding resistance after tendon repair, and may, therefore, have an effect on the result of tendon repair.

Animals↗

The A3 pulley.

The tendon-pulley geometry and gliding resistance with and without the A3 pulley were compared in 6 fresh human cadaver fingers. We measured the x-ray images of the distal A2 pulley-tendon angle and proximal A4 pulley-tendon angle with varying degrees of proximal interphalangeal joint flexion between 0 degrees and 120 degrees before and after A3 pulley resection. The gliding resistance of the flexor digitorum profundus tendon under the A2 pulley was also measured at varying tendon-pulley angles. With the A3 pulley removed, the tendon-pulley angle significantly increased compared with the A3 intact state. The gliding resistance between tendon and pulley quadratically increased as the tendon-pulley angle increase from 0 degrees to 60 degrees. These results indicate that the A3 pulley might serve to reduce tendon-pulley gliding resistance by reducing the tendon-pulley angle during finger flexion.

Biomechanical Phenomena↗

Comparison of mechanical properties of various suture repair techniques in a partially lacerated tendon.

The technique of surgical repair for zone two flexor tendon injuries has been debated extensively throughout the years, yet adhesion formation, suture rupture, and suture locking on the pulley edge remain possible consequences of a poor repair. The partially lacerated tendon is especially challenging to treat since there can be justification for not intervening surgically. In a partial laceration canine model we measured failure load and suture gap formation for tendons repaired with the Lee, modified four-strand Savage, Kessler, modified Kessler, and Augmented Becker core suture techniques and with a simple running peripheral suture. The modified Kessler (106.3 N, SD 18.8 N) and modified Savage (108.2 N, SD 19.9 N) repair techniques had a significantly higher failure load than the Lee (85.0 N, SD 20.6 N) suture method (P < 0.05), while there were no differences among the other techniques. There were no significant differences in resistance to gap formation among the repair techniques, with the mean values ranging from 38.9 N/mm (SD 15.7 N/mm) using the simple running suture to 53.2 N/mm (SD 25.8 N/mm) with the Kessler repair. The mean load to produce a 1.5 mm repair site gap ranged from 71.1 N (SD 21.5 N) in the Lee repair to 91.3 N (SD 22.2 N) in the Augmented Becker repair although there were no significant differences among repair methods. All repair methods were much weaker than tendons left unrepaired (184.7 N, SD 41.3 N).

Animals↗

Change in diagnosis among orthopedists compared to non-orthopedists in the management of acute knee injuries.

OBJECTIVE: Uncertainty regarding diagnosis is associated with lower patient satisfaction and can lead to delays in definitive treatment and to inappropriate use of resources. We sought to compare change in diagnosis among orthopedists and non-orthopedists caring for a community based cohort of individuals with incident acute knee injuries. METHODS: We conducted a longitudinal investigation of a population based cohort of Olmsted County residents with their first episode of acute knee injury occurring between January 1, 1993, and December 31, 1995. We reviewed the entire (inpatient and outpatient) medical records for these patients and collected extensive clinical data on all diagnoses made (including possible and probable) and the specialty of the attending physician(s) making them. Diagnoses were categorized as: (1) meniscus injury, cruciate injury, or osteochondral fracture; (2) ligament injury, patellar instability, patellar injury; or (3) sprain, strain, injury (unspecified). Diagnostic switches were defined as changes from one diagnostic category to another, or the addition or subtraction of a diagnostic category. We then examined the quality of the documented evidence supporting meniscal, ligamentous, and cruciate diagnoses (at initial evaluation) by comparing the clinical evidence to the recommendations outlined by the American Academy of Orthopaedic Surgeons clinical algorithm on acute knee injury. Analyses were conducted comparing (1) the number of diagnostic switches and (2) the quality of the documented evidence among those cases initially cared for by orthopedists and those cared for by non-orthopedists, using logistic regression analysis adjusting for age, sex, and injury severity. The influence of these variables on costs of care was also examined. RESULTS: There were 664 patients (361 men and 303 women) in our study population, with an average age of 36.0 years (minimum 17, maximum 87). Of these, 324 were excluded because they only had one clinical encounter for their acute knee injury. Of the remaining 340, 59 (17.4%) were initially cared for by an orthopedist and 211 (62.1%) were cared for by an orthopedist at some time during their care. Diagnostic switches were significantly less frequent in the group who were cared for by orthopedists (55% vs 74%, p < 0.001). This result persisted after adjusting for age, sex, and severity (p = 0.003). The proportion of cases whose diagnoses were supported by evidence was significantly higher among the group whose first attending physician was an orthopedist (63.0% vs 37.6%, p = 0.002). Both change in diagnosis (p < 0.001) and physician specialty (p < 0.001) were statistically significant predictors of costs of care. CONCLUSION: Compared to non-orthopedic care, orthopedic care for acute knee injury was associated with fewer changes in diagnosis, and diagnoses made by orthopedists were more likely to be supported by evidence. However, even after adjusting for severity, orthopedic care remained significantly more costly than non-orthopedic care.

Acute Disease↗

Flexor tendon-tendon sheath interaction after tendon grafting: a biomechanical study in a human model in vitro.

A human cadaver tendon sheath model was used to study the differences in excursion resistance of tendons that might be considered as sources of clinical tendon grafts. The flexor digitorum profundus and superficialis tendons, the extensor indicis proprius tendon used in its normal proximal-distal orientation, the extensor indicis proprius tendon used in a reversed distal-proximal orientation, and the palmaris longus tendon were studied in 7 fingers. The intrasynovial tendons (the flexor digitorum profundus and superficialis tendons and the reversed extensor indicis proprius tendon) produced less excursion resistance (p < .05) than the extrasynovial tendons (the normally oriented extensor indicis proprius tendon and the palmaris longus tendon). In contrast to studies measuring resistance against a single pulley, resistance within a complete tendon sheath may be affected by contact with other structures, particularly in joint extension.

Aged↗