Search PubMed⌕ Search

Biomedical subjects

P Bouyard

Publications and source records attributed to P Bouyard.

77 records · Page 5Linked to original sources
PubMedDate not supplied

[Four benzamides (metoclopramide, sulpiride, sultopride and tiapride) effects on the oestrus cycle of the female rat: a comparative statistical study (author's transl)].

The comparative study of 4 Benzamides effects on the oestrus cycle of female rats has been done. These compounds were administered once daily for 21 consecutive days (1; 0,1; and 0,001 mg.kg-1.SC) on Wistar AF SPF rats smears. Our data show that sulpiride and sultopride suppress oestrus cycle substituted by a permanent dioestrus, while metoclopramide only extend the duration of the cycle and tiapride does not influence oestrus cycle.

Amisulpride↗
PubMedDate not supplied

[Experimental study of sulpiride-bromocriptine association on the female rat estrous cycle (author's transl)].

The effects of joint treatment by sulpiride (1 mg . kg-1 S.C. pro die) and bromocriptine (3 mg . kg-1 S.C. pro die) on female rat estrous cycles were carried out on a group of ninety animals for a twenty-one days period. The results thus obtained show that: (i) bromocriptine alone does not disturb the estrous cycle, (ii) when given both with sulpiride, it prevents from this psycholeptic's estrous cycle blockade, (iii) finally, it leads to the regression of a blockade induced by an eight days sulpiride pretreatment. Therefore, it is likely that these two drugs act antagonistically at tuberoinfundibular dopaminergic receptors involved in the prolactin and gonadotropins release.

Animals↗