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Biomedical subjects

P Bouche

Publications and source records attributed to P Bouche.

At least 109 records · Page 6Linked to original sources
PubMed1988

[Cervical magnetic stimulation. A new method of bilateral phrenic nerve stimulation for use in clinical practice].

The stimulation of the phrenic nerves in the neck is one of the techniques for the examination of diaphragmatic contractility. Current methods are restricted by their painful (transcutaneous stimulation) or even potentially dangerous nature (needle stimulation). We have tested both the feasibility and the validity of using magnetic stimulation (SMC) to stimulate the phrenic nerves. This method is painless and devoid of any side effects. Three healthy subjects have been studied using an EMG and transdiaphragmatic pressure measurements (Pdi.) Pdi values obtained by SMC (36.5 +/- 13.5 cm H2O) and their relation to maximal Pdi (22.6 +/- 7%) and to the Pdi at the time of maximal sniff-Pdi sniff (34.7 +/- 8%) were comparable to those values obtained using other methods and were reproducible. The preliminary results show that SMC is a technique for the study of the phrenic nerve and diaphragm which has the advantage of simplicity in use, is repeatable and is completely innocuous.

Adult↗
PubMed1988

[Progressive muscular atrophy localized in the hand. Monomelic form of motor neuron disease?].

Ten new cases of distal amyotrophy localized in an upper limb are reported. In all cases, patients were young males. The onset of the neurological impairment was always progressive during one to three years. The disease remained stable with a follow-up study of at least three years. Electrophysiological and neuroradiologic results were in keeping with an involvement of the anterior horn cell, in agreement with similar studies found in the literature. The relatively benign evolution of this syndrome, in regard to the usual prognosis of the other forms of motor neuron disease, especially amyotrophic lateral sclerosis, has to be outlined.

Adolescent↗
PubMed1986

[The accessory deep peroneal nerve. Electrophysiologic study].

The extensor digitorum brevis muscle is innervated by the deep peroneal nerve. In some cases it has an additional innervation by the accessory deep peroneal nerve, a branch of the superficial deep peroneal nerve. The motor nerve conduction study with detection on the extensor digitorum brevis allows to detect such an anatomical variation. It has been found in twelve cases out of 67 subjects. In two cases it was bilateral and in two other cases the extensor digitorum brevis muscle was innervated by the accessory deep peroneal nerve alone. That anatomical variation has to be known in order to avoid errors in interpretating the peroneal motor nerve conduction velocity.

Adult↗
PubMed1986

Peripheral neuropathy in systemic vasculitis: clinical and electrophysiologic study of 22 patients.

Twenty-two patients with evidence of systemic vasculitis and peripheral neuropathy were clinically and electrophysiologically investigated in a retrospective study. Ten had a polyarteritis nodosa, 6 a probable polyarteritis nodosa, and 6 a Churg-Strauss syndrome. Nine patients presented clinically with mononeuropathy or mononeuropathy multiplex considered typical of ischemic involvement of peripheral nerve; nine had more diffuse neuropathy, two of them a symmetric polyneuropathy. EMG examination revealed more diffuse neuropathy than clinically predicted. Findings were of acute or subacute axonal neuropathy.

Adult↗
PubMed1986

[Chloroquine neuromyopathies: 4 cases during antimalarial prevention].

Four cases of chloroquine neuropathy presented two points of particular interest: 1) these were all young women with strictly prophylactic doses of chloroquine (100 mg/24 h); two patients showed pronounced loss of weight; 2) signs of myogenic lesions were apparent in only one patient whereas clinical and electric signs of neurogenic involvement were observed in all 4 cases. Biopsy in 3 patients (muscle in one and muscle and nerve in two) failed to show characteristic vacuoles; in one case mild segmental demyelinization was present. A favorable course was obtained in all cases after discontinuation of chloroquine, with dramatic recovery from the motor deficit. Pharmacokinetic studies in 1 patient showed abnormally high chloroquine levels at initial assay with slow elimination after its discontinuation.

Adult↗
PubMed1985

[The anterior interosseous nerve syndrome. A rare lesion of a median nerve branch in the forearm. A case].

Apparently spontaneous and isolated lesions of the anterior interosseous nerve--a purely motor branch of the median nerve in the forearm--are extremely rare. Their clinical manifestations are fairly stereotyped, consisting of paralysis restricted to the long flexor muscle of the thumb, the deep flexor muscle of the index finger and the quadrate pronator muscle, without sensory disorders. The diagnosis is confirmed by electromyography. The syndrome may caused by traumas of the forearm or may develop spontaneously, although underlying anatomical abnormalities which may act as predisposing factors are not infrequently found in this case. The natural outcome may be favourable, but surgery may be required to release the nerve.

Adult↗
PubMed1985

Chorea and polycythaemia.

Two patients with chorea and polycythaemia vera are described. The literature on this rare association is reviewed and its pathophysiology discussed.

Aged↗
PubMed1985

[Peripheral neuropathies associated with monoclonal gammapathies. Value of electrophysiologic studies].

An electrophysiological study was performed in 19 patients with polyneuropathy associated with a monoclonal gammopathy. This study has shown some difference according to the type of the gammopathy and the benign or malignant nature of the disease. Patients with benign IgM gammopathy are in an homogenous group. In every case the neuropathy is of the demyelinating type. In the other groups, the neuropathy is less homogenous. Most of the time it was predominantly of axonal type. Within the myeloma group, the neuropathy is more severe and the denervation pattern is marked.

Adult↗
PubMed1985

Focal glomerulosclerosis associated with Charcot-Marie-Tooth disease.

This report describes a new case of the rare association of focal glomerulosclerosis with a peroneal muscular atrophy of the Charcot-Marie-Tooth type. The young patient was admitted with a nephrotic syndrome. A terminal renal failure rapidly developed. Numerous chronic nephropathies were known in the patient's family. The ultrastructural study of the renal biopsy revealed a focal fusion of the epithelial foot processes, thickened and pleated mesangial basal laminae, vacuolated podocytes and small intranuclear clear inclusions. The Charcot-Marie-Tooth disease was of the hypertrophic type. According to a review of the literature and to further information concerning the follow-up of the 5 previously reported cases, the prognosis of the nephropathy is guarded with progression to end-stage renal disease in a few years. This case represents the 6th reported case of focal glomerulosclerosis associated with Charcot-Marie-Tooth disease.

Adolescent↗
PubMed1985

[Painful legs and unstable toes].

Five patients presented with the painful legs and moving toes syndrome as defined by Spillane et al. (1971). A peripheral nervous disorder was present in 4 of these cases while the fifth patient showed evidence of a central lesion. Results of clinical and electrophysiologic investigations in the 4 peripheral cases, are compared with data from the literature.

Adult↗
PubMed1985

[Spasm or dimpling of the hypothenar eminence].

Bilateral hypothenar muscular spasm ("dimpling") was discovered in a 62 year-old man. The spasms consisted of recurrent arrhythmic contractions of the palmaris brevis muscle. E.M.G. showed no signs of denervation but the contractions could be stopped by infiltration of the ulnar nerve by xylocaine. Apparently, this syndrome has previously been reported in only two cases. Its clinical and electromyographic characteristics are similar to hemifacial spasm. Compression of the ulnar nerve after its division at the wrist could be a cause.

Diagnosis, Differential↗
PubMed1984

Miller Fisher syndrome: clinical and electrophysiologic evidence of peripheral origin in 10 cases.

Clinical and electrophysiologic data recorded in patients with Fisher syndrome characterized by ophthalmoplegia, ataxia, and areflexia are presented. Cases with limb weakness or pleocytosis in the CSF were excluded, according to Fisher. Ten patients were selected. All had hand and foot numbness. A large amount of protein without cell reaction was found during the third week of illness in serial CSF examinations. EMGs showed very slight limb involvement without spontaneous activity, and in most cases, facial muscles exhibited a denervation pattern. Distal motor nerve conduction velocity on limbs and F wave latencies were normal, whereas the sensory nerve action potentials were altered in all but one case when tested (seven out of eight cases). By means of blink reflex study performed in four patients, no significant pattern of brainstem dysfunction was discovered. The authors discuss the preeminent role of peripheral nerve lesions with regard to the ataxia and ophthalmoplegia.

Adolescent↗