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Biomedical subjects

P Bottin

Publications and source records attributed to P Bottin.

7 recordsLinked to original sources
PubMed2003

Therapeutic issues in women with epilepsy.

Approximately 20% of people with epilepsy are of childbearing potential and about 3 to 5 births per thousand will be to women with epilepsy. Both epilepsy and antiepileptic drugs can cause specific problems in women and embryos (less than 8 weeks of gestational age) or foetuses (more than 8 weeks of gestational age). The aim of this paper is to discuss therapeutic issues for the management of women with epilepsy: initiation of antiepileptic therapy, contraception, pregnancy, breast feeding and menopause. Some fertility issues are also discussed.

Anticonvulsants↗
PubMed2003

[Statins for the brain?].

Whether cholesterol lowering decreases risk of stroke has long remained unclear. Large epidemiological studies have found only weak links between cholesterol levels and stroke. Recent studies with statins, more potent cholesterol lowering agents, have now demonstrated significant reductions of stroke incidence and total mortality when administered for secondary prevention in patients with wide ranges of cholesterol values. It remains unknown if a statin is superior to others for the secondary prevention of stroke.

Brain↗
PubMed1991

[Fissure caries: the correlation of clinical and radiological data].

The goal of this research was to evaluate the conventional means of clinical (mirror and probe examination) and radiological diagnosis (bitewing radiographs) of occlusal caries of first permanent molars during the post eruptive period. These teeth showed colored or non-colored fissures, and none of them had conservative or preventive obturations, or dentinal caries. Four experienced dentists independently evaluated the trials, diagnosed the lesions and advised a treatment. The effective lesions were shown by opening minimal preventive cavities, which were then obturated with amalgam. The results showed the lack of precision for the early diagnostic means of initial pit- and fissures-caries, and differences and errors of evaluation performed by the dental professional with respect to their diagnosis and proposed therapeutic choice. The effective lesions demonstrated the high incidence of pit- and fissure-caries in permanent molars during the post eruptive period.

Adolescent↗
PubMedDate not supplied

[Reversible posterior leukoencephalopathy syndrome].

Reversible posterior leukoencephalopathy refers to a clinicoradiological syndrome observed in patients presenting with acute or subacute symptoms of various intensity including seizures, headache, vomiting, confusion and visual abnormalities. The radiological features are reversible bilateral white matter abnormalities predominantly located in the posterior regions of the cerebral hemispheres, demonstrated by computed tomography or, better, by magnetic resonance imaging. This syndrome mostly occurs in patients with hypertensive encephalopathy or in immunosuppressed patients. The recognition of this syndrome is critical as delay in the diagnosis or treatment can result in permanent neurological deficit while early prompt control of blood pressure or withdrawal of causative drugs can reverse the syndrome.

Adult↗