Search PubMed⌕ Search

Biomedical subjects

P Bol

Publications and source records attributed to P Bol.

At least 91 records · Page 5Linked to original sources
PubMed1997

[Fifty years of dissertations by dentists].

From 1947 the faculties of dentistry of the Dutch universities are entitled to grant Ph.D. grades for dental theses. In the fifty years that have elapsed since, about 500 dentists defended their thesis; the vast majority (6/7) during the second half of the period. This article describes the first thesis (dating from 1956-1973) of each of the five dental faculties that have existed in the Netherlands, followed by a short analysis of the entire group of 500 dissertations. In recent years dissertations are hardly ever written in Dutch, English taking over nearly entirely. Subjects in the field of social dentistry seem to loose foot. The increase in numbers of dental dissertations is stagnating (at a level of 20-30/year), just as is the case for medical theses (600-700/year).

Academic Dissertations as Topic↗
PubMed1991

[Costs and benefits of vaccination against Haemophilus influenzae type b].

In the Netherlands, Haemophilus influenzae type b (Hib) causes invasive disease in hundreds of children every year; meningitis is the most frequent and most severe infection. Children from the age of 6 months can be protected against Hib-diseases by conjugated vaccines. The financial consequences of the introduction of such vaccine into the state vaccination programme are considered in a cost-effectiveness analysis. Some elements in the analysis are still uncertain, such as the price and the schedule and method of administration of the vaccine. Presumably, the costs and benefits will be in balance, if one vaccine dose will cost about 7 US $+ and if the administration can be combined with the present programme of vaccinations against diphtheria, whooping cough, poliomyelitis and tetanus.

Bacterial Capsules↗
PubMed1991

Differences in subtype distribution of Haemophilus influenzae type b from carriers in the general population and patients with meningitis.

Twenty-four Haemophilus influenzae type b strains from 836 children and young adults in an open population were subtyped by outer-membrane-protein (OMP) analysis on sodium dodecyl sulphate-polyacrylamide gels, lipopolysaccharide serotyping and biotyping. The results were compared with those obtained with H. influenzae type b strains from 97 patients with meningitis in the same city (Amsterdam). OMP subtype 1 was significantly more common among the CSF isolates than in carrier strains (82% vs 50%; p less than 0.002). The other OMP subtypes found among carriers were rarely isolated from patients. The lipopolysaccharide serotype and biotype distribution did not differ between the two groups. The combination of OMP subtype 1, lipopolysaccharide 1, biotype I was much more common in isolates from patients than in those from carriers (71% vs 42%; p less than 0.01). The data suggest that various H. influenzae type b subtypes are less virulent than those commonly isolated from invasive infections.

Adult↗