Biomedical subjects
P Bol
Publications and source records attributed to P Bol.
[Intestinal infections with Escherichia coli type O157].
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[Helicobacter pylori and the stomach].
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[Two chapters from the medical history of this century: antibacterial therapy].
The antibiotic era brought adequate therapies for bacterial infections and began with the introduction of sulphonamides (discovered earlier by Domagk) in 1935 and penicillins (discovered earlier by Fleming) in the course of World War II. Notwithstanding the usual description as 'discoveries', they were the fruits of systematic investigations for chemicals with antibacterial properties and little or no toxicity for the host. Despite the role of serendipity in the discovery of penicillin, the bactericidal moulds that Fleming observed had fallen on fertile soil: a laboratory where the search for antibacterial drugs had been going on for years.
[Alzheimer's disease 1].
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[Alzheimer's disease 2].
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[Smoking and pregnancy].
Smoking is disadvantageous for health in every respect. This is a fortiori the case during pregnancy. Pregnant women who smoke burden their unborn child with a mixture of hundreds of tobacco combustion products, dozens of which have been proved to be harmful, apart from the negative influence of the smoke induced blockade of the haemoglobin by carbon monoxide. Since the embryonic and foetal tissues which are formed in a short period, are particularly vulnerable, many detrimental effects can be observed. The fertility rate of women who smoke is reduced and their risk of abortion, miscarriage and preterm delivery is increased. Babies born to women who smoked during pregnancy have lower birth weights and are less developed. They run an increased risk of many disorders including asthma and even cancer. Their cancer risk seems even to be increased in adulthood. Smoking fathers also damage the development of their unborn child.
[Herpes simplex infections].
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[Considerations for dental care during pregnancy].
Traditionally, general dentists have been reluctant to treat pregnant patients due to uncertainty of the risks that might be imposed on both the mother and the fetus. However, preventive, emergency, and routine dental procedures are all suitable during various phases of a pregnancy, with some treatment modifications and initial planning. This article will review some of the physiologic changes and oral pathology associated with pregnancy, and how these alterations affect dental care for the patient. A brief discussion concerning the risks and benefits of radiation, certain medications, and pre-natal fluoride is also given. Additionally, an overview of possible obstetric emergencies that may arise during a general dental appointment is presented with treatment options outlined.