Biomedical subjects
P Barone
Publications and source records attributed to P Barone.
[Myelin figures in the liver after fixation with glutaric aldehyde injected into the portal vein].
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[Neurologic syndrome of acute H2S poisoning. Observation of 4 cases].
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[Kawasaki disease in Sicily: description of the first case with giant coronary aneurysm].
A case of Kawasaki disease with early development of giant coronary artery aneurysm is reported. The delay in the diagnosis and consequently in the use of correct therapy has conditioned the outcome of the illness. We don't know the predictive factors of cardiac complications, but steroid treatment in our patient probably had an important role in the cardiac damage. The use of echocardiography in the evaluation of coronary aneurysm has confirmed the sensitivity, specificity and predictive value of this technique in detecting cardiac lesions.
Hepatitis B vaccination in young nurses of a general hospital.
Several reports have clearly demonstrated that intradermal way of administration of hepatitis B vaccine represent a valid alternative to the intramuscular route, producing an high percentage of seroconversion. The characteristics of the intradermal way, short time of immunization and lower cost, have induced us to conduct a clinical trial among 116 healthcare workers in a hospital setting, which represent an high risk group especially at their first admission to the hospital. 99 selected participants (average age 22 years, range 17-27) received, after screening for HBV markers, 5 mcg of vaccine intradermally on the volar surface of the forearm, according to the schedule 0, 15, 30 and 45 days. Serum samples were collected after one month from the last inoculation of vaccine. The percentage of seroconversions obtained was significantly high (93.9%) confirming that intradermal vaccination with hepatitis B vaccine may be appropriate in providing a rapid protection for certain population subgroups.
An early-type hypersensitivity (ETH) to hepatitis B surface antigen as a quick and economic screening test for a vaccination program.
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