Search PubMed⌕ Search

Biomedical subjects

P Baillie

Publications and source records attributed to P Baillie.

At least 19 recordsLinked to original sources
PubMed1989

Pregnancy without ovarian function. A case report.

A 38-year-old nulliparous woman suffering from premature menopause was stimulated with oestradiol valerate in order to create an artificial endometrial cycle. Three oocytes were donated by a woman on an in vitro fertilisation cycle and were inseminated with the patient's husband's sperm. These were then transferred into the patient's uterus after the endometrium had been primed with progesterone to change it to the secretory phase. Pregnancy resulted and proceeded well. Gestation was terminated at the 34th week by caesarean section and 2 healthy boys and 1 girl were delivered.

Adult↗
PubMed1988

The changes in fetal habituation patterns due to a decrease in inspired maternal oxygen.

Habituation is widely regarded as a basic form of learning. A fully functioning central nervous system is probably required for a normal habituation pattern. Habituation of the behavioural response to vibroacoustic stimulation was studied in 23 normal human fetuses whose gestational age was 36 or more weeks. Eighteen were tested whilst their mothers breathed either air or a 12% oxygen in nitrogen mixture. The test was repeated the following day with the order of the gases reversed. In addition five fetuses were tested while their mothers breathed air on both occasions. Of the 18 fetuses 17 had a normal habituation pattern when tested in air but only two had a normal pattern when their mothers breathed 12% O2. Four of the five fetuses tested both days in air had normal patterns on the second day. Altering the amount of inspired maternal O2 alters the fetal habituation pattern.

Female↗
PubMed1979

The use of human chorionic gonadotropin in recurrent abortion.

Important unresolved problems associated with recurrent abortion are aetiology, prognosis and management. This communication describes hormonal monitoring in pregnancy of groups of patients treated with human chorionic gonadotropin (HCG). The outcome is compared with that in an untreated normal group and an untreated group with recurrent abortions.

Abortion, Habitual↗
PubMed1979

The accuracy of maternal observation of fetal movements.

The accuracy of maternal observation of fetal movements was assessed in 20 patients during the last trimester of pregnancy. The effect of factors such as smoking, obesity, education and gestational age were correlated with maternal observations to establish the accuracy of the latter.

Female↗
PubMed1978

Reversal of active labour. A case report.

The clinical course of primiparous patient who presented in premature labour at 31 weeks' gestation is described. Cervical dilatation was reversed from 9 cm and pregnancy continued for 6 days. The possible causes and mechanism are discussed and the implications are considered.

Adult↗
PubMed1978

Haemodialysis in pregnancy. A case report.

A successful outcome of haemodialysis in a pregnant patient with chronic glomerulonephritis is reported. After a stable period of 9 years, pregnancy resulted in a definite deterioration of renal function. The importance of establishing biological maturity in preference to gestational maturity is stressed.

Adult↗
PubMed1976

A comparison of the uterine beta2-adrenoreceptor selectivity of fenoterol, hexoprenaline, ritodrine and salbutamol.

A study was undertaken to compare the uterine beta2-adrenoreceptor selectivity of fenoterol, hexoprenaline, ritodrine and salbutamol. The drugs in doses having an equivalent effect on uterine activity, were randomly administered as an intravenous bolus to 10 patients who had been induced at term. The cardiovascular and uterine effects of the drugs were recorded. The rise in maternal pulse rate was significantly less (P less than 0,001) after the administration of hexoprenaline when it was compared with fenoterol, ritodrine, and salbutamol. Hexoprenaline proved to be the most chronotropically beta2-selective drug, having the least effect on the beta1-adrenoreceptors of the heart, for an equivalent effect on the uterus. Blood pressure changes were less significantly different between the drugs. The clinical use in obstetrics of a highly beta2-selective sympathomimetic drug is discussed.

Albuterol↗
PubMed1976

Uterine and cardiovascular effects of beta2-selective sympathomimetic drugs administered as an intravenous infusion.

The uterine and cardiovascular effects of fenoterol, hexoprenaline, ritodrine and salbutamol, given as intravenous infusions in equivalent and therapeutic dosages in oxytocin-induced labour, were studied and compared. All the drugs were effective in reducing the uterine activity to less than 30% of the original. The effect on the cardiovascular system was to produce a moderate tachycardia and a widening of the pulse pressure by raising the systolic and decreasing the diastolic blood pressures.

Adrenergic beta-Agonists↗
PubMed1976

The effects of the fenoterol hydrobromide (Partusisten) aerosol on uterine activity and the cardiovascular system.

Fenoterol hydrobromide (Partusisten) aerosol was used in a placebo-controlled, double-blind, double crossover trial to study its effects on oxytocin-induced uterine contractions and the maternal cardiovascular system. The active and placebo aerosols were each administered a total of ten times or twice each in five patients who were in established oxytocin-induced labour with intact membranes. Five puffs, of 200 mug each, of the active aerosol reduced uterine activity by more than half; the effect on the cardiovascular system was to cause a mild tachycardia and to widen the pulse pressure.

Aerosols↗
PubMed1975

Beta2-selectivity of fenoterol. Comparison of intravenous and aerosol administration.

Aersol administration of fenoterol was compared with intravenous infusion in 30 patients who were undergoing induction of labour. In 11 cases, an increased uterine beta2-selectivity was demonstrated. This, apart from the ease of administration, makes aerosol the mode of administration of choice in some cases. Possible reasons for this are discussed.

Aerosols↗
PubMed1975

Clinical classification of perinatal deaths.

The purpose of classifying perinatal mortality is to assist in its prevention. A clinical classification has been devised an applied to 506 perinatal deaths which occurred among 15 251 deliveries in the Peninsula Maternity Services in Cape Town during 1972. Prematurity, accidental haemorrhage and fetoplacental inadequacy are the three main causes of perinatal loss. There appears to be a lower incidence of congenital abnormalities in the Cape Cape Coloured community. Detection of the premature labour group, the aplication of prevention and the early delivery of the fetus which is unable to withstand the stress of intra-uterine life will lower the perinatal mortality rate.

Adolescent↗