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Biomedical subjects

P B Clark

Publications and source records attributed to P B Clark.

32 records · Page 2Linked to original sources
PubMed1978

Urethral tumours.

A series of 33 patients with urethral tumours has been studied to assess the risk of dissemination by endoscopic diathermy. This risk is less than that of cystourethrectomy. Urethral tumours should be treated like the vesical tumours they follow and so closely resemble: by endoscopic treatment while they remain small, sparse and superficial; by cystourethrectomy as soon as they become larger and more extensive. Recurrence of tumour in the urethral stump following cystectomy should always be treated by urethrectomy.

Aged↗
PubMed1975

Sarcoidosis of the penis treated by radiotherapy.

A case of sarcoidosis of the penis is reported which initially caused ulceration around the external urethral meatus. After an immediate response to steroid therapy, the disease recurred locally in spite of continuing therapy and involved other parts of the penis. Partial amputation of the penis was performed but further ulceration occurred at the cut ends of the corpora cavernosa in the penile stump. This ulceration healed after radiotherapy.

Biopsy↗
PubMed1967

The effect of temperature and anoxia of rat-kidney slices on their subsequent respiration.

1. Rat-kidney slices were kept, aerobically and anaerobically, at 4 degrees , 20 degrees and 38 degrees , for 0.5-24hr. The oxygen consumption was then measured at 38 degrees . 2. After 6hr. of storage at 4 degrees the rate of oxygen consumption was the same as controls, but after 12 and 24hr. of storage the oxygen consumption fell by 22 and 32% respectively; there was no difference between the slices kept aerobically and anaerobically for periods of 2-24hr. at 4 degrees . 3. Anaerobic storage at 20 degrees for 2hr. did not affect the subsequent rate of oxygen consumption, but after 4 and 6hr. the anaerobically stored tissue showed loss of oxygen consumption. Aerobic storage had no effect for 6hr. 4. There was a marked fall in the capacity to consume oxygen after 0.5hr. at 38 degrees without oxygen. 5. Kidney slices stored at 4 degrees lost nitrogen. The presence of oxygen did not affect this nitrogen loss.

Animals↗