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Biomedical subjects

P Auger

Publications and source records attributed to P Auger.

At least 91 records · Page 5Linked to original sources
PubMed1972

Tinea faciale.

Explore the source record for details and available documents.

Antifungal Agents↗
PubMed1967

Sudden, severe mitral insufficiency.

Five male patients with sudden, severe mitral insufficiency due solely to ruptured chordae tendineae or papillary muscle had an abrupt onset of symptoms of left and right heart failure and the sudden appearance of a harsh, widely propagated apical pansystolic murmur. None had a history of rheumatic fever. All were in sinus rhythm and had but mild left atrial and ventricular enlargement. Giant left atrial "v" waves were characteristic and exceeded pulmonary artery pressure in two instances.In contrast, when ruptured chordae tendineae were superimposed on chronic rheumatic mitral insufficiency, females predominated and there was a long history of disability. Atrial fibrillation, less elevation of left atrial pressure, and marked left atrial and ventricular enlargement were characteristic. These latter patients closely resembled patients with chronic rheumatic mitral insufficiency alone.It is concluded that the syndrome of sudden, severe mitral insufficiency develops if ruptured chordae tendineae occur on a previously normal or insignificantly diseased mitral valve. If ruptured chordae tendineae are superimposed on chronic rheumatic mitral insufficiency, the syndrome resembles that seen in the latter alone.

Adult↗
PubMed1966

Muscular subaortic stenosis: the initial left ventricular inflow tract pressure as evidence of outflow tract obstruction.

Two types of intraventricular pressure differences within the left ventricle of man are described. The first is encountered in cases of muscular (or fibrous) subaortic stenosis, in which the outflow tract pressure distal to the stenosis (and proximal to the aortic valve) is low, whereas all pressures recorded in the left ventricle proximal to the stenosis, including that just inside the mitral valve (the initial inflow tract pressure) are high.The second type of intraventricular pressure difference may be recorded in patients without muscular subaortic stenosis when a heart catheter is advanced to the left ventricular wall in such a manner that it becomes imbedded or entrapped by cardiac muscle in systole. Such an entrapped catheter records a high intraventricular pressure that is believed to reflect intramyocardial tissue pressure, which normally exceeds intracavitary pressure. In such cases the initial inflow tract pressure is not high and is precisely equal to the outflow tract systolic pressure, i.e. both are recording intracavity pressure. This type of intramyocardial to intracavitary pressure difference may also be encountered in the left ventricle of dogs.The recent suggestion that intraventricular pressure differences in the left ventricle of cases of muscular subaortic stenosis are due to catheter entrapment by cardiac muscle is refuted by using the initial inflow tract pressure as the means of differentiation between the two types of intraventricular pressure differences outlined.

Animals↗
PubMed1965

[Thyroid suppression test].

A test in which thyroid function is suppressed was evaluated in regard to its ability to confirm the diagnosis of hyperthyroidism in borderline cases. An effort was made to establish a standard technique by determining the required duration of administration of tri-iodothyronine. Twenty-seven normal controls received tri-iodothyronine (T(3)) for a 10-day period, and 24-hour I(131) uptake was determined after three, six and 10 days. Twenty-two normal controls were similarly studied after four days of T(3) treatment. Twenty-one patients with an elevated I(131) uptake without goitre or toxicity, 10 with non-toxic goitre and 11 with toxic goitre were also studied. The T(3) suppression test was found to be particularly useful in distinguishing toxic goitre from euthyroid patients with an elevated I(131) uptake. Four days of suppression were found to be sufficient for purposes of evaluation in a large majority of cases.

Adult↗
PubMedDate not supplied

RP 59500, a new streptogramin highly active against recent isolates of North American staphylococci.

To assess the potential clinical utility of RP 59500, 10 investigators from separate locations in the United States and Canada each tested approximately 200 current isolates of staphylococci (Staphylococcus aureus and coagulase-negative staphylococci) by a standard protocol. RP 59500 was highly active (MIC90 < or = 2 micrograms/ml) against all strains, including those that were resistant to oxacillin, ciprofloxacin, erythromycin, and spiramycin.

Coagulase↗