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Biomedical subjects

P Audra

Publications and source records attributed to P Audra.

50 records · Page 3Linked to original sources

[Radiopelvimetry in cephalic presentation].

The value of radiopelvimetry is increasingly under question in cases of brow presentation except in cases of scarred uterus. Radiopelvimetry, in which the antero-posterior, transverse median and bi-sciatic dimensions were determined was carried out in 564 patients who gave birth during 1984. It would appear that cases of major narrowing have virtually disappeared and that most frequently encountered is transverse median narrowing. In this group of patients, the presence of a radiologically abnormal pelvis doubled the incidence of cesarians carried out during labor. Even if the biparietal diameter is included, it is very difficult to define a definite lower limit for eutocia. Radiopelvimetry is a useful indication but must leave an important place for the labor test.

Cesarean Section↗

[Cesarean section before the end of 32 weeks of amenorrhea].

The authors report the results of 59 caesarean operations in which 74 children were born before the end of the 32nd week of amenorrhoea. The gross mortality was 21.9% and the corrected mortality 18.5%. 7.9% of the infants had major neurological sequellae and 8.6% mild sequellae. 65.2% are alive and well with normal psychomotor development. The follow-up has been between 1 and 5 years. The factors that influence survival and the indications for caesarean section at this time are reviewed and discussed.

Birth Weight↗

[Fetal death in utero].

152 cases of fetal death in utero are reported. The most frequent etiologies were: vasculorenal syndromes: 28.3 p. cent, idiopathic DPPNIs and RCIUs: 28 p. cent, accidental causes (trauma, funicular syndromes): 19.5 p. cent. Cause of death was unknown or imprecise in 18.4 p. cent of cases. Repeated fetal deaths in utero were rare: 5 observations. The authors consider the management of fetal death in utero, associated immunological problems and how to deal with subsequent pregnancies.

Autoimmune Diseases↗

[Severe postpartum hemorrhage].

The authors report 95 cases of post-partum haemorrhage estimated at one litre or more seen in the Department of Obstetrics between 1979 and 1982 for 11 662 deliveries. Classical treatment combining artificial delivery or uterine manual evacuation-oxytocics led to the arrest of bleeding in 73 cases. Severe haemorrhage persisted in 22 cases, including 13 patients who were found to be suffering from a coagulopathy. Treatment of these severe forms is based upon: local haemostasis (in the presence of inertia, prostaglandins must be used before surgery) and correction of the coagulation disorder by substitution therapy providing the missing factors.

Female↗

[Treatment of cancer of the uterine cervix by surgery alone].

The authors report a series of 434 patients with invasive cancer of the uterine cervix treated with primary surgery. The results are equivalent to those reported by others who treated cervix cancer with radiotherapy. Post-operative radiotherapy did not improve the results except in the most advanced forms (pT2b, pN1 or 2) when it increases the disease-free interval without altering the survival probability at 5 years. For the clinical stages I, IIA and IIB proximal (infiltration of the parametrium limited to the proximal part) surgery is the elective treatment. In stage IIB distal and for "operable" Stages III and IV, a combination of chemotherapy-surgery and radiotherapy is suggested.

Clinical Trials as Topic↗

[Is it legitimate today to perform large rotations with forceps?].

Many authors argue against the practice of large forceps rotations on the basis of a threefold increased neonatal risk compared to the use of forceps for anterior presentations. The experience of the Obstetric Clinic of Hôpital Edouard-Herriot in Lyon, of 81 major forceps rotations from a series of more than 10 000 births, is very similar to that of Chiswick in Manchester, based on 86 cases. In nearly one quarter of the neonates, there are discreet, transient neurological signs which disappear within one week and, did not leave any permanent sequelae. It would appear that large rotations should not be totally forbidden, but that their indications have to be carefully considered, especially in cases of foetal distress. An experienced obstetrician can perform these rotations: in experienced hands, they are often straightforward, but in cases of unexpected difficulty (1 case in 10 or 20) it should be immediately abandoned and a caesarian should be performed.

Apgar Score↗

[Second-trimester abortion: a difficult, unresolved problem].

The authors review the various methods proposed for the late evacuation of the uterus. They report their experience of intra-amniotic injection of prostaglandins and, more recently, the use of extra-amniotic injections. They have found this latter technique to be unsatisfactory. Evacuation following dilatation under local anaesthetic, despite a few complications, appears to be effective... but the problem is far from being resolved.

Abortion, Induced↗

[The pregnancy occuring during oral contraception or intra uterine device (i.u.d.) (author's transl)].

It seems possible to answer most of the questions asked by our patients after failure of the contraception. The pill stopped within the first five weeks of gestation has never been responsible of congenital malformations. When this treatment is prolonged during the pregnancy, a risk of masculinisation of female fetus exists. No severe malformations has been reported. The I.U.D. does not play a role in the frequency of tubal pregnancy. The I.U.D. must be removed when a pregnancy occurs to prevent the risk of sepsis.

Abnormalities, Drug-Induced↗

[Cesarean section before the end of 32 weeks' gestation. Apropos of 91 neonatal case reports].

78 cesarean sections (CS) were performed before 32 weeks of gestation over a period of six years in a obstetric clinic; 91 premature infants were born; the rate of CS at this period of time represented 0,47% of total birth. 84 premature infants were transferred to the neonatal unit located in the same clinic; 3 were dead in utero and 4 just after delivery. 69 infants survived (78%) but 6 had severe sequelae (spastic diplegia, epilepsy and RLF) at one year of age and 7 had minor sequelae.

Birth Weight↗