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Biomedical subjects

P Alomar

Publications and source records attributed to P Alomar.

34 records · Page 2Linked to original sources
PubMed1989

[Campylobacter pylori's sensitivity to the bactericidal action of human serum].

The sensitivity to the bactericidal power of the human serum was evaluated on 8 strains of C. pylori, 8 strains of C. jejuni, 2 strains of C. coli and 2 strains of C. fetus. Each of them was incubated at 37 degrees C in the presence of a complete pool of human sera, the same pool after inactivation of the complement, and trypticase soy broth (control). After 0, 15, 30 and 60 minutes the capacity to grow in blood agar plates (count of colonies) incubated in microaerophillic conditions for 3 days was evaluated. In this experimental study it was shown that C. pylori has a rapid and complete sensitivity to the human serum and, particularly, to the complement; this could be one of the factors that determine its lack of invasive capacity.

Blood Bactericidal Activity↗
PubMed1989

[Effectiveness of ClNa-esculin broth for the rapid identification of the Enterococcus genus].

The efficacy of the ClNa-esculine broth for the rapid identification (2 hours) of the species of the genus Enterococcus was evaluated and compared with the conventional biochemical methods requiring an incubation of 18-24 hours. Out of the 274 evaluated strains, 171 were positive for this investigation; 160 of them corresponded to Enterococcus spp (100%). The sensitivity of the test was 100%, the specificity 99.1%, the positive predictive value 99.3% and the negative predictive value 100%.

Culture Media↗
PubMed1989

[Human infections caused by Enterobacter sakazakii. Microbiologic considerations].

The clinical and microbiological features of four patients with positive cultures for Enterobacter sakazaii are reported. They corresponded to two wound exudates, one appendicitis and one newborn conjunctivitis. The biochemical and physiological characteristics of this organism are analyzed (inability to ferment d-sorbitol and production of a non-diffusible yellow pigment); its difficult identification and the clinical rarity of its isolation are discussed. The relevant literature is reviewed.

Adult↗
PubMed1989

[Analysis of the prevalence of anti-Campylobacter pylori antibodies detected in a healthy human population].

A study was made of the prevalence of anti C. pylori in the healthy adult population. The analytical method used was indirect immunofluorescence. An analysis was made of 231 sera (122 males and 109 females) from subjects 20 to 82 years-old. The global positivity detected was 21.1%. There was a slight rise in the percentage of positivities as age increased, reaching the maximum rate in the group over 50 years (2.1%). The titers detected were low and unrelated to age. No significant differences by sex were found in the subjects analyzed.

Adult↗
PubMed1988

Efficacy of the enteric pathogen screen card in the presumptive identification of Salmonella enteritidis.

The efficacy of the Enteric Pathogen Screen (EPS) card as a rapid method for identification of Salmonella spp. isolated in stool cultures was studied. Of the 120 lactose-negative, sucrose-negative, H2S-producing colonies tested, 74 were identified as Salmonella enteritidis by conventional methods. The reading of the EPS card after 2 h of incubation yielded a sensitivity of 47.2% and a specificity and positive predictive value of 100%, with a negative predictive value of 54.1%. In the final reading of 4 h, a sensitivity of 97.2% and a specificity of 86.9% were obtained, with a positive predictive value of 92.3% and a negative predictive value of 95.2%.

Bacteriological Techniques↗
PubMed1988

The maternal-infant center in the control of hepatitis B.

A seroepidemiologic survey of HBV infection was carried out in four population groups served by the Maternity Hospital of Majorca, an island in the Mediterranean. The prevalence of HBV markers (HBsAg, anti-HBs, anti-HBc), determined by enzyme-immunoassay, reached 17.2% among 864 parturients, 17.2% in 783 hospital personnel, 2.7% and 19.2% among the 186 children and 73 husbands of parturients with no HBV markers, 22.8% and 43.8%, respectively, among the 44 children and 48 husbands of HBsAg chronic carrier parturients. The prevalences of HBsAg in the same groups reached 0.9%, 1.5%, 0% and 0%, 11.4% and 2.1%, respectively. The carrier state represents 50% of all infection cases among children and 4.8% among husbands of carrier women. The prevalence of markers, which was especially high among personnel working in maintenance services (39.1%), on surgical wards (35.3%), among midwives (27.6%) and in cleaning and laundry services (27.1%), and laboratories (21.4%), is used as an indicator in defining priorities for the vaccination of people at risk. Sixty-seven newborn babies of HBsAg carrier mothers were administered one dose of HBIG and three doses of hepatitis B vaccine; at 12 months of age, the seroconversion rate was 98.5%, whereas 1 child (1.5%) became a chronic carrier. Maternity hospitals represent the ideal centers in which to carry out the detection of HBsAg in pregnant women prior to parturition, to ensure that all newborns of chronic carrier women receive passive-active immunization, and to screen their family contacts and vaccinate those who are found susceptible to the infection.

Adult↗
PubMed1977

Treatment of respiratory infections with fosfomycin.

Results are presented for a series of 29 patients, 14 males and 15 females, with serious respiratory infections, in which fosfomycin proved effective. In all cases the study was completed by bacteriological, clinical, radiological and analytical controls. The average dose was 6 g/day (3 g orally and 3 g intramuscularly) for 1 or 2 weeks. The four isolated were P. aeruginosa, E. coli, Klebsiella-Enterobacter and D. pneumoniae. Overall sensitivity percentages were best for fosfomycin, gentamicin and colistin. Of the 29 germs isolated, only one strain of P. aeruginosa became resistant: this represents 3% resistance development. No side effects of intolerance or signs of hepatorenal insufficiency were observed during the treatment. Of the 29 patients treated, 22 were clinically cured, denoting 76% success.

Anti-Bacterial Agents↗
PubMedDate not supplied

Non-typhi Salmonella bacteraemia.

We reviewed retrospectively the clinical records of patients with non-typhi Salmonella bacteraemia in our hospital from 1979 to 1988. During the study period 45 non-typhi Salmonella bacteraemias were diagnosed in 43 patients. Ten patients were under one year old and 11 were over 60. Seven cases of sepsis presented in patients with AIDS. Only three episodes were nosocomially acquired. In two of three patients the bacteraemia was preceded by an episode of acute gastroenteritis and one third presented without gastroenteritis. Complications and mortality were infrequent in spite of the differing degrees of adequacy of antibiotic treatment which was inappropriate in many cases. We have attempted to assess optimal antibiotic therapy, taking into account the duration and means of administration, in different groups of patients with nontyphi Salmonella bacteraemia.

Acquired Immunodeficiency Syndrome↗