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Biomedical subjects

P Ablanedo

Publications and source records attributed to P Ablanedo.

23 records · Page 2Linked to original sources
PubMed1988

Central pontine and extrapontine myelinolysis following correction of severe hyponatremia.

A chronically hyponatremic patient developed neurological features of pontine level disconnection following the raising of serum sodium. At autopsy histopathological examination confirmed the presence of myelinolysis in the central pons and similar symmetrical lesions in the thalamus. In chronic hyponatremic patients, more than the rapidity of correction, the magnitude of the osmolar change may predispose to development of these lesions.

Demyelinating Diseases↗
PubMed1984

[Nemaline myopathy: apropos of a case].

Authors present a girl without familiar antecedents of consanguinity with mild motor deficiency, hypotonicity and obesity during infancy, with progressive posterior healing. The girl did not present Marfan's habit or special phenotype, and had small hypertrophy of calfs. There was not recurrent respiratory infections. EMG was myopathic and muscle dependent seric enzymes (CPK, ALD, LDH...) were normal. Radiographically films showed increased relationship fat-muscle and pathology by MO and ME confirmed the presence of small sticks in muscle fibers. After evaluating the case as a neomutation, the genetic counseling is made.

Biopsy↗
PubMedDate not supplied

Splenic artery aneurysms.

Nine aneurysms of the splenic artery are reported. The most remarkable etiopathogenic factors are female predominance, pregnancy, portal hypertension, and arteriosclerosis. Histologic findings are significant in woman: subendothelial thickening, internal elastic lamina fragmentation, medial fibrodysplasia, and accumulation of acid glycosaminoglycans in both subintimal and medial layers. In addition to these changes, two women suffering rupture during pregnancy presented microcystic degeneration. Six patients were operated and in 5 instances aneurysmectomy with splenectomy was performed; in the remaining patients the spleen was preserved. All six patients survived the operation and the postoperative period was free of problems in 5 instances. A woman suffering from gestational rupture required reoperation because the preserved spleen was bleeding and the fetus dead. The utility of arteriography in all patients with portal hypertension and the need to include this problem in the diagnostic methodology of shock occurring during pregnancy are emphasized.

Adult↗