Search PubMed⌕ Search

Biomedical subjects

P A Perry

Publications and source records attributed to P A Perry.

At least 55 records · Page 3Linked to original sources
PubMed1995

Effect of supplemental dietary calcium on the development of DOCA-salt hypertension in weanling rats.

This study characterizes the response to dietary calcium in DOCA-salt hypertension. Body weight, systolic blood pressure, and total serum calcium levels were compared among normotensive control rats, DOCA-salt hypertensive rats treated with calcium carbonate (CaCO3) augmentation, and DOCA-salt hypertensive rats without supplementary dietary calcium. Dietary calcium augmentation prevented the rise of blood pressure that is normally produced by DOCA-salt. Attenuation in systolic blood pressure was independent of weight loss or total serum calcium and may be linked to alterations in calcium homeostasis that are seen in both human and experimental hypertension. Thus this study provides important data that may assist in further explicating the role that alterations in calcium homeostasis play in DOCA-salt hypertension. Further, these data may also be important in the identification of a nonpharmacological intervention for testing in humans.

Animals↗
PubMed1994

Feminist empiricism as a method for inquiry in nursing.

Feminist empiricism may provide a valuable approach for the acquisition, evaluation, and integration of biological knowledge in nursing epistemologies. This article discusses feminist empiricism as a method for inquiry in nursing. Proponents of feminist empiricism strive to work within the current political, social, and scientific structures while acknowledging that all three of these structures must change if less distorted epistemologies are to emerge. Hypertension in women is used to illustrate how feminist empiricism could be used to modify the traditional scientific approach. The argument is made that the androcentricism of the traditional scientific approach must be changed in order to include the problematics of women. Moreover, women must have a central role in determining the problematics of both health and illness in women. A philosophical stance embracing holism cannot deny biological phenomena or preclude research on these phenomena. Theorists and scientists in nursing have a unique opportunity to reconceptualize biological phenomena, from a holistic perspective, in the development of epistemologies for nursing. An argument for the use of basic research as a quantitative methodology, from a feminist perspective, is made. The appropriateness, for nursing, of basic research methodologies to generate knowledge about biological processes, which are within nursing's scientific domain, are discussed.

Female↗