Search PubMed⌕ Search

Biomedical subjects

P A Mardh

Publications and source records attributed to P A Mardh.

10 recordsLinked to original sources
PubMed1994

Seroepidemiologic study of Chlamydia pneumoniae and other chlamydial species in a hyperendemic area for trachoma in the Sudan.

Sera of inhabitants of Angola village in central Sudan were investigated for the prevalence of antibodies to Chlamydia trachomatis, C. pneumoniae, and C. psittaci by the microimmunofluorescence (MIF) test. Clinical examination of 616 persons showed that the village is hyperendemic for trachoma. Of the 448 children examined, 334 (75%) had signs of active trachoma. The corresponding prevalence in the 168 adults was 25%. Using MIF, antibodies to C. trachomatis were found in the sera of 27 (81%) children and of 37 (88%) adults with trachoma. Antibodies to C. pneumoniae occurred in 13% and 24% of the preschool and school trachomatous children, respectively, and in 64% of the adults, which reflects earlier exposure to C. pneumonia in the Sudan than generally reported from temperate zones. Antibodies to C. psittaci were found in 6% of the children less than 16 years old and in 17% of the adults. Of the patients with trachoma, 16% had antibodies to both C. trachomatis and C. pneumoniae. The prevalence of multiple antibodies to Chlamydia increased with age. Antibodies to all three species occurred in 3% of the patients. The study does not support the existence of protective immunity between C. pneumoniae, C. trachomatis, and C. psittaci, as shown by the high prevalence of chlamydial antibodies in the hyperendemic trachoma community studied.

Adolescent↗
PubMed1984

Factors that might influence the outcome of studies on the aetiology and epidemiology of acute pelvic inflammatory disease.

An overview is presented of the various factors that might influence the outcome of aetiological and epidemiological studies of pelvic infections in women. Some diversities of opinion in these respects might be explained by i.a. inprecise definitions, lack of simple and specific diagnostic methods, differences in patient selection and laboratory techniques.

Adolescent↗
PubMed1976

The incidence and aetiology of respiratory tract infections in general practice--with emphasis on Mycoplasma pneumoniae.

The incidence of respiratory tract infections in patients seeking medical advice at a community care centre (Dalby) during 1973 and 1974 was studied. About every third patient seen at this primary health station presented with signs of such infections. In the age groups less than 10, 10-19, 20-39, 40-59 and greater than or equal to 60 years, respiratory tract infections accounted for 65, 45, 32, 18 and 9% of the fotal number of diagnoses made during 1974. The aetiology of acute respiratory tract infections in a series of patients seen at this health station was studied. The series included randomly selected cases, but excluded children under seven years of age and patients presenting with signs of acute otitis media and tonsillitis. Attempts to establish the aetiology were made on the basis of the history, the clinical examination, and cultures for beta-haemolytic streptococci and Mycoplasma pneumoniae, complement foxation tests for influenza A and B, para-influenza 1, 2, and 3, adeno, cytomegalovirus and respiratory syncytial virus, and Chlamydia psittaci. Paul-Bunnell test and tests for cold agglutinins were also performed. With this test battery, an aetiological diagnosis was obtained in only 33% of the 101 patients studied. The findings suggest an infection with M.pneumoniae in 16%, with beta-haemolytic streptococci in 9%, and with viruses (adeno and para-influenza) in 7% of the patients. The present communication highlights the role of M.pneumoniae in upper respiratory infections, as few data have appeared on such infections in patients seen in general practice. The difficulty of establishing the aetiology of respiratory tract infections and the consequent treatment dilemma is discussed.

Adolescent↗
PubMed1976

A study of complications in preterm deliveries after prolonged premature rupture of the membranes.

The risk of infection for mother and baby after spontaneous rupture of the membranes was evaluated in a prospective study of 24 patients with ruptured membranes before the 36th week of pregnancy. The mean length of pregnancy after rupture was 10 days and 2 hours. Only patients harboring Group B streptococci or E. coli in the urogenital tract were treated with antibiotics (during delivery). With the exception of 1 woman, all patients harbored one or more pathogens in the urogenital tract. Four mothers were infected but all recovered. One of 26 infants died from infection. The study did not confirm any association between prolonged rupture of the membranes and the frequency of idiopathic respiratory distress syndrome, nor did it contradict attempts to actively prolong pregnancy after rupture of the membranes.

Bacterial Infections↗