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Biomedical subjects

P A Busby

Publications and source records attributed to P A Busby.

33 records · Page 2Linked to original sources

Underlying structure of auditory-visual consonant perception by hearing-impaired children and the influences of syllabic compression.

The identification of consonants in (a)-C-(a) nonsense syllables, using a fourteen-alternative forced-choice procedure, was examined in 4 profoundly hearing-impaired children under five conditions: audition alone using hearing aids in free-field (A), vision alone (V), auditory-visual using hearing aids in free-field (AV1), auditory-visual with linear amplification (AV2), and auditory-visual with syllabic compression (AV3). In the AV2 and AV3 conditions, acoustic signals were binaurally presented by magnetic or acoustic coupling to the subjects' hearing aids. The syllabic compressor had a compression ratio of 10:1, and attack and release times were 1.2 ms and 60 ms. The confusion matrices were subjected to two analysis methods: hierarchical clustering and information transmission analysis using articulatory features. The same general conclusions were drawn on the basis of results obtained from either analysis method. The results indicated better performance in the V condition than in the A condition. In the three AV conditions, the subjects predominantly combined the acoustic parameter of voicing with the visual signal. No consistent differences were recorded across the three AV conditions. Syllabic compression did not, therefore, appear to have a significant influence on AV perception for these children. A high degree of subject variability was recorded for the A and three AV conditions, but not for the V condition.

Adolescent↗

Perceptual studies on cochlear implant patients with early onset of profound hearing impairment prior to normal development of auditory, speech, and language skills.

Psychophysical studies were conducted on three prelingual and two postlingual cochlear implant patients. Auditory sensations were produced by electrical stimulation of the residual nerve fibers of the auditory nerve by means of a multiple-electrode cochlear implant. The psychophysical performance of the prelinguals was, in general, poorer than that of the postlinguals; prelingual performance was poorer for repetition rate and electrode position identification, gap detection, and durational and numerosity judgments. Improved performance with time, however, was consistently observed for the prelinguals in the above-mentioned psychophysical tasks. There were significant individual differences in the amount of improvement among the three prelinguals. Speech perception studies were also conducted on the three prelingual patients. The speech perception performance of the three prelingual patients was much poorer than that of postlingual patients in general, and was consistent with their poorer psychophysical performance described above.

Adolescent↗

Initial experience with children using the Nucleus 22 Channel cochlear implant.

The Nucleus 22 Channel cochlear prosthesis developed by the University of Melbourne and Cochlear Pty Ltd is now being used in over 90 clinics worldwide, in fourteen countries and fifteen languages. A total of thirty adolescents and thirty-nine children have now been implanted in Australia, America and more recently Germany. There have been no significant postoperative complications, and the device has been successfully programmed in children as young as two years nine months. Comprehensive evaluation and training programs are being undertaken with each implanted child to assess long term development of speech perception and communication skills. The average postoperative stimulation time for most of the children implanted is around 3 months, so as yet, little data has been recorded on these patients. However, the two original children implanted in Melbourne have now been using their speech processors in excess of 18 months. The focus of this paper will be on the performance of these two children.

Child↗

A multiple-electrode intracochlear implant for children.

A multiple-electrode intracochlear implant that provides 21 stimulus channels has been designed for use in young children. It is smaller than the adult version and has magnets to facilitate the attachment of the headset. It has been implanted in two children aged 5 and 10 years. The two children both lost hearing in their third year, when they were still learning language. Following implantation, it was possible to determine threshold and comfortable listening levels for each electrode pair. This was facilitated in the younger child by prior training in scaling visual and electrotactile stimuli. Both children are regular users of the implant, and a training and assessment program has been commenced.

Child↗

Preliminary results for the cochlear corporation multielectrode intracochlear implant in six prelingually deaf patients.

The preliminary results from this study indicate that some prelingually deaf patients may get worthwhile help from a multiple-electrode cochlear implant that uses a formant-based speech processing strategy. It is encouraging that these improvements can occur in young adults and teenagers. The results for two children are also encouraging. A 10-year-old child obtained significant improvement on some speech perception tests. It was easy to set thresholds and comfortable listening levels on a 5-year-old child, and he is now a regular user of the device. There are, however, considerable variations in performance among the prelingual patients, which may be related to the following factors: whether they have had some hearing after birth, the method of education used, the motivation of the patient, and age at implantation.

Adolescent↗

Underlying dimensions and individual differences in auditory, visual, and auditory-visual vowel perception by hearing-impaired children.

Vowel perception studies were conducted on a group of four adolescent children with congenital profound sensorineural hearing impairments in the three conditions of audition alone, vision alone, and audition plus vision. Data were analyzed using the ALSCAL multidimensional scaling procedure to identify the underlying dimensions and individual differences in dimension emphasis. The three dimensions obtained from the analysis of data for the audition alone condition were interpreted as the parameters of first and second formant frequencies, and vowel length. The one dimension for the vision alone condition was interpreted as the parameter of the width of the internal lip opening. The three dimensions for the audition plus vision condition were interpreted as the parameters of first formant frequency, vowel length, and the width of the internal lip opening. Subject variations in parameter preferences were observed for the audition alone and audition plus vision conditions but not for the vision alone condition.

Adolescent↗

Psychophysical studies for two multiple-channel cochlear implant patients.

Psychophysical studies were conducted on two multiple-channel cochlear implant patients to examine the nature of the hearing sensations produced by electrical stimulation of auditory nerve fibers using electrodes at different sites in the scala tympani (one electrode at a time). Both time-invariant stimuli, whose parameter values did not vary in time, and time-varying stimuli, specified by a linear variation in parameter values, were used. A sharpness ranking study using time-invariant signals suggested that the hearing sensations produced by different electrodes varied from dull to sharp in an apical to basal direction in the scala tympani. A categorization study showed that the hearing sensations produced by two adjacent electrodes (1.5 mm apart) were rarely confused for a restricted range of time-invariant pulse rates. Discriminability studies by a same-different procedure for stimuli with pulse rate below 250 pps showed: (1) relative difference limens of 6% to 12% for time-invariant pulse rates, and 9% and 13% for time-varying pulse rates; (2) stimuli with time-varying electrode position differing in the direction of electrode trajectory were readily discriminated; and (3) the discrimination of time-varying pulse rates deteriorated with decreases in the duration of the variation, while the discriminability of single-electrode trajectories was the same for the three durations: 25, 50, and 100 ms. A speech processing strategy was also proposed on the bases of these results.

Auditory Perception↗

Cochlear implant place psychophysics 1. Pitch estimation with deeply inserted electrodes.

Numerical estimation of pitch was performed by 8 adult subjects implanted with cochlear prostheses manufactured by Cochlear Limited. The electrode arrays had been inserted into the scale tympani to between one and one and a half turns of the cochlea. Using bipolar stimulation, the pitch estimates for each subjects showed an overall reduction with insertion depth of the stimulated electrode. However, for several subjects, after decreasing regularly for the more basal electrodes, pitch estimates showed an abrupt decrease, followed in some cases by a region of low pitch. Two of the subjects, implanted with a modified electrode array, the '20 + 2' which allowed monopolar in addition to bipolar stimulation, exhibited an abrupt decrease in pitch estimate with bipolar but not with monopolar stimulation. In these two subjects, for stimulating electrodes inserted more deeply than about three quarters of a turn, bipolar stimuli produced lower pitch sensations, and presumably more apical neural excitation patterns, than monopolar stimuli.

Adolescent↗

Cochlear implant place psychophysics. 2. Comparison of forward masking and pitch estimation data.

Results for forward masking and numerical estimation of pitch were compared in a group of 6 adult subjects implanted with cochlear prostheses manufactured by Cochlear Limited. Data were collected for bipolar + 1 stimulation in all subjects, and for stimulation in one other mode, either common ground or monopolar, for all subjects but one. The pitch data show various irregularities and in each case can be seen to be broadly consistent with the corresponding forward masking data. It is shown that a 'centre of gravity' of the forward masking distribution varies with masker electrode in a manner that is qualitatively very similar to the variation of pitch estimate. It is suggested that, while pitch estimation results are consistent with those from forward masking, the latter contain more detailed information that may be useful in understanding intersubject variations in speech comprehension.

Adolescent↗

A multiple-channel cochlear implant. An evaluation using an open-set word test.

Multiple-channel electrical stimulation of the hearing nerve in conjunction with speechreading has helped two post-lingually deaf patients with total hearing losses understand running speech in every day situations. This has been confirmed using open-set phonetically balanced word tests, where the patients achieved 60% and 40% scores with isolated-words, and 80% and 73% for phonemes-in-isolated words. The tests also showed that the cochlear implant improved word recognition by a factor of four in one patient and two in another, compared with speechreading alone. The speech processor used, extracted the voicing frequency and energy, and the frequency and energy of the dominant spectral peak in the mid-frequency range. The parameters for voicing determined the rate of stimulation for all electrodes, and the parameters for the dominant spectral peak in the mid-frequency range determined the site of electrode stimulation and current level.

Cochlear Implants↗

Electrode discrimination by early-deafened cochlear implant patients.

Electrode discrimination was measured in six cochlear-implant patients who became profoundly deaf prior to the full development of auditory and speech skills. The cochlear implant manufactured by Cochlear Limited was used. Comparisons were made between two electric stimulation paradigms and two data collection procedures. The paradigms consisted of electrode trajectories and electrodes with random variation in electric current levels. The data collection methods consisted of an adaptive procedure to obtain difference limens and a method of constant stimuli that gives psychometric functions of discrimination performance. Data were collected for reference electrodes at the apical, mid, and basal positions on the array. The psychometric functions showed that discrimination performance improved with increases in the spatial separation between reference and comparison electrodes. The difference limens were similar to the corresponding spatial separation estimated from the psychometric function in most cases. The discrimination performance of most patients was consistent across the two stimulation paradigms. Difference limens were 1-4 electrodes from the reference electrode for most patients. There were differences in performance across patients and the three positions on the array.

Adolescent↗

Studies of prosody perception by cochlear implant patients.

Prosodic information is conveyed to normally-hearing listeners by variations in acoustic fundamental frequency, amplitude envelope, and duration of speech segments. This study measured cochlear implant patients' sensitivity to these parameters in electrically coded speech. The psychophysical discrimination of electric parameters used to code prosodic information, were examined, together with prosody perception using speech processing strategies which modified the contributions of these parameters. Patients were implanted with the Cochlear Limited prosthesis and used the MPEAK speech processing strategy. In the psychophysical studies, difference limens were measured for steady-state and time-varying stimuli, of different pulse rates and pulse durations, over a series of different stimulus durations. These limens were obtained using an adaptive procedure which converged on the 50 per cent correct point. In the prosody perception studies, performance was measured for the MPEAK strategy and for strategies which modified the contributions of pulse rate and pulse duration. Data were collected for five tests of prosodic contrasts. Difference limens for steady-state pulse rates were larger at higher rates (17 per cent at 400 pulses/s) than at lower rates (6 per cent at 100 pulses/s). For some patients, limens for the time-varying pulse rates were larger than those for the steady-state pulse rates while for the other patients, the limens were similar. Difference limens for pulse duration were 0.3 dB, corresponding to 4 per cent of the dynamic range, for steady-state stimuli and doubled in size for the time-varying stimuli. Prosody perception performance was generally poorer for the modified strategies than for the MPEAK strategy, suggesting that the removal of information coded by pulse rate and pulse duration reduced the perception of prosodic contrasts.

Aged↗