Discovery of an HLA-B*35 Null Variant, HLA-B*35:636N in Two Unrelated Individuals.
Characterisation of the novel HLA-B*35:636N allele in two bone marrow donors from the Russian State Registry.
Humans↗
Biomedical subjects
Olga Makhova
Publications and source records attributed to Olga Makhova.
Seven New Non-Synonymous Alleles of HLA-B Characterised by Next-Generation Sequencing.
Seven novel HLA-B alleles were detected during the routine HLA typing process.
Humans↗
Comparative HLA Alleles and Haplotypes of Bone Marrow Volunteers Recruiting in the Asian and European Parts of Russia.
HLA typing of 9126 haematopoietic stem cell donors living in the Asian and European parts of Russia and identifying themselves as Russians was performed using NGS technology in 2-field resolution at the HLA-A, HLA-B, HLA-C, HLA-DRB1, and HLA-DQB1 loci. The study of donors in the Asian part of Russia disclosed 77 alleles at the HLA-A locus, 111 at the HLA-B locus, 58 at the HLA-C locus, 54 at the HLA-DRB1 locus, and 26 at the HLA-DQB1 locus. Donors of the European part of Russia are characterised by the following allelic diversity: 87 alleles at the HLA-A locus, 136 at the HLA-B locus, 72 at the HLA-C locus, 67 at the HLA-DRB1 locus, and 37 at the HLA-DQB1 locus. The most common five-locus haplotype in both populations is HLA-A*01:01 ~ HLA-C*07:01 ~ HLA-B*08:01 ~ HLA-DRB1*03:01 ~ HLA-DQB1*02:01. Throughout the study, 26 new alleles were revealed.
Humans↗
Detection of Five Novel and Confirmation of Two HLA Class II Alleles.
Seven HLA class II alleles were detected and confirmed.
Humans↗
Three Novel Alleles, HLA-DRB1*01:159, HLA-DRB1*04:402 and HLA-DRB1*15:240, Identified by Next Generation Sequencing.
Three novel HLA-DRB1 alleles were identified during routine next generation sequencing.
Humans↗