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Biomedical subjects

O W Brown

Publications and source records attributed to O W Brown.

28 records · Page 2Linked to original sources

Computerized tomography following abdominal aortic surgery.

Computerized tomography (CT) is an accurate, noninvasive method for direct imaging of the retroperitoneal space. We have evaluated its effectiveness in diagnosing postoperative aortic graft complications. CT provides an excellent display of the prosthetic graft material. Graft infections, graft hematomas, graft occlusions, anastomotic aneurysms, and true aneurysms can be detected with CT. We believe CT is the diagnostic screening procedure of choice for most patients with suspected aortic graft complications.

Aged↗

Recurrence and rupture of an axillary artery aneurysm.

Aneurysm of the axillary is an uncommon type of peripheral artery aneurysm. most of these aneurysms are symptomatic and present with signs and symptoms of thromboembolism. Rupture of an axillary artery aneurysm is uncommon. We present a patient who ruptured a recurrent true axillary artery aneurysm four years after surgical treatment by exclusion and bypass of the aneurysm. We believe that the preferred treatment of an axillary artery aneurysm is resection and insertion of an end-to-end interposition graft.

Aged↗

Abdominal aortic aneurysm and coronary artery disease.

To delineate the role of routine preoperative coronary angiography in patients undergoing elective abdominal aortic aneurysm resection, we reviewed the records of 422 such patients at the Mayo Clinic, Rochester, Minn. One hundred seventy-three patients (41%) had a history of either myocardial infarction or angina pectoris; 146 (35%) had a previous myocardial infarction; 111 (26%) had a history of stable angina. Six patients underwent coronary artery bypass grafting prior to aneurysmorrhaphy. Ten patients (2.4%) died within the first 30 postoperative days. Seven deaths (1.7%) were secondary to myocardial infarction. Mortality from myocardial infarction was 0.8% in patients who had no history of coronary artery disease and 2.9% in patients with a history. Mortality was not increased in elderly patients. Coronary angiography should be selectively obtained prior to elective aneurysmorrhaphy. A 0.8% mortality from myocardial infarction in patients without a history of coronary artery disease and an overall mortality of 1.7% do not justify routine coronary angiography prior to elective resection of an abdominal aortic aneurysm.

Adult↗

Abdominal aortic aneurysm and horseshoe kidney. A different perspective.

We report a case of abdominal aortic aneurysm with horseshoe kidney. The anatomic distribution of the renal vessels, the position of the thin portion of the isthmus of the kidney, and concern for the preservation of the sexual potency of the patient made standard aneurysm repair untenable. We describe a method of repair by exclusion of the aneurysm.

Aneurysm↗

The influence of competitive flow on graft patency.

To evaluate the effects of competitive flow, bilateral aorto-iliac ePTFE grafts, 10 cm in length and with an internal diameter of 6 mm, were placed in ten mongrel dogs. On one side the external iliac artery was ligated (the control side); on the opposite side (the experimental side) flow continued through the native aorto-iliac system, as well as the graft, to allow a situation of competitive flow. Flow measurements showed the experimental graft carried 38.6% of the total blood flow going to the ipsilateral external iliac artery. After 30 days the grafts were exposed and patency and flow were evaluated by Doppler ultrasound. The control side showed 60% patency; all of the grafts on the experimental side were occluded. In addition, complete endothelial healing was observed at the occluded ostia of all experimental grafts. We conclude that competitive flow does influence graft patency and that graft thrombosis appears to be a relatively early phenomenon, as evidenced by the endothelial healing which occurred.

Animals↗

Distal bypass graft for limb salvage.

The use of "distal bypass grafts" in the lower extremity for limb salvage is controversial among vascular surgeons. Twenty-nine "distal grafts", defined as grafts with their distal anastomosis within 3 inches (7.5 cm) of the ankle malleoli, were performed. All patients selected for the procedure had an intact pedal arch in continuity with the grafted vessel and limited gangrene of the foot. The grafts consisted of 4 patients with grafts to the peroneal artery, 3 to the anterior tibial artery, 5 to the dorsalis pedis artery and 17 to the posterior tibial artery. Of the 29 grafts attempted, 22 (76%) continued to function from 6 months to 4 1/2 years postoperatively. The 22 successful grafts consisted of autogenous vein greater than 4 mm in diameter. Twenty-two limbs were salvaged by distal bypass more than 24 hours postoperatively were important prognostic indications. Careful attention to technique and the use of magnification were believed to be important aspects of successful graft construction.

Aged↗