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Biomedical subjects

O Vuia

Publications and source records attributed to O Vuia.

At least 37 records · Page 2Linked to original sources
PubMed1975

The cortical form of subacute necrotizing encephalopathy of the Leigh type. A light- and electron-microscopic study.

The present paper is a clinico-pathological study of a 14-year-old boy with a chronic, progressive occipital syndrome for which he was operated upon. Postoperatively, metabolic acidosis developed. Pathological anatomy revealed spongy necrosis of the thalamus and corpora quadrigemina with the typical histological features of Leigh's necrotizing encephalopathy. Similar necrotic lesions had developed in the occipital cortex. At this level apart from the typical foci, cavitating necrosis was found as well as involvement of the smaller vessels of the pial circulation. Electron microscopy revealed vascular and glial changes suggestive of primary mesenchymoglial dystrophy. The histiocytes presented intracytoplasmic multiplication of lysosomes and their transformation into lipofuscin pigment. The changes demonstrate a juvenile cortical form of Leigh's subacute necrotizing encephalopathy.

Adolescent↗
PubMed1975

Striato-nigral degeneration and Shy-Drager syndrome (idiopathic orthostatic hypotension).

The present paper reports on a case which evolved clinically with a Parkinson syndrome and attacks of orthostatic hypotension. Dystrophic lesions were found in the substrantia nigra, putamen and autonomic bulbo-medullary axis. This case demonstrates that striato-nigral degeneration of the Adams, van Bogaert and van der Eecken type and the Shy-Drager syndrome (orthostatic hypotension with neurologic syndrome) are part of the same pathiologic entity respesenting nervous multisystem degeneration developing in the presenium.

Aged↗
PubMed1975

The pineal gland and Rosenthal fibres.

115 pineal glands, collected from patients who died from various neurologic and visceral diseases, were studied. The Rosenthal fibres (RF) forming gliosis is consistently evident in the subependymal tissue around the gland, in the pineal recessus and in the intrapineal glial proliferation. In several instances the focal gliosis exhibited a central cystic degeneration. The RF-forming gliosis of the pineal gland appears independent of the basic diseases and of the process of atrophy and degeneration of the gland parenchyma. The embryonic development of the pineal gland could explain why the formation of RF may be considered a quasi-physiologic process of this region.

Adolescent↗
PubMed1975

Central neuroblastic tumour associated with smooth muscle fibers. A study in the optic and electron microscopes.

The present paper is a study of a microcystic intraspinal tumour that developed in a 4-year-old child. The histologic examination showed the presence of neuroblastic elements developing next to smooth muscle fibers. The tumour had diffusely invaded the meninges, presenting a marked collagen reaction. Ultrastructurally, the neuroblastic elements exhibited an arrangement proper to the neural tube and the presence of a series of osmiophil neurosecretory dense-core vesicles. The fine structural morphology of the smooth muscle fibers was clearly revealed, the cells containing microfibrils and being delimited by a basement membrane. The muscular fibers were visibly in contact with the blood vessels. These aspects demonstrate that the medullomyoblastoma is a malignant bidermal teratoid tumour of the central nervous system. Dysgenesis of the ectomesenchyma may be considered to stand at the basis of the development of this type of tumour.

Child, Preschool↗